Michel Sylvestre, Institut national de la recherche scientifique

Research

Read how they describe their research on their Institut national de la recherche scientifique profile.

Environmental biotechnologies biocatalysis Enzyme engineering

Latest papers

Engineering Burkholderia xenovorans LB400 BphA through Site-Directed Mutagenesis at Position 283.
Applied and environmental microbiology · 2020
Metabolism of Doubly para-Substituted Hydroxychlorobiphenyls by Bacterial Biphenyl Dioxygenases.
Applied and environmental microbiology · 2015 · senior author
Engineering a thermostable fungal GH10 xylanase, importance of N-terminal amino acids.
Biotechnology and bioengineering · 2015 · senior author

All 15 publications

Latest funding

Remodeling Rieske-type bacterial dioxygenases to change catalytic properties
NSERC · 2012 · Principal investigator
$130,000
Biochemical, genetics and molecular biology of the bacterial biphenyl catabolic pathway enzymes
NSERC · 2007 · Principal investigator
$225,000
Plant chemicals to promote rhizoremediation of POP-contaminated brownfields
NSERC · 2007 · Principal investigator
$170,000

All 15 grants and awards

15 publications.

01

Engineering Burkholderia xenovorans LB400 BphA through Site-Directed Mutagenesis at Position 283.

Li J, Min J, Wang Y, Chen W, Kong Y, Guo T, Mahto JK, Sylvestre M, Hu X

Applied and environmental microbiology2020

DOI: 10.1128/aem.01040-20 PMID: 32709719

02

Metabolism of Doubly para-Substituted Hydroxychlorobiphenyls by Bacterial Biphenyl Dioxygenases.

Pham TT, Sondossi M, Sylvestre M

Applied and environmental microbiology2015Senior author

DOI: 10.1128/aem.00786-15 PMID: 25956777

03

Engineering a thermostable fungal GH10 xylanase, importance of N-terminal amino acids.

Song L, Tsang A, Sylvestre M

Biotechnology and bioengineering2015Senior author

DOI: 10.1002/bit.25533 PMID: 25640404

04

Optimizing Polychlorinated Biphenyl Degradation by Flavonoid-Induced Cells of the Rhizobacterium Rhodococcus erythropolis U23A.

Pham TT, Pino Rodriguez NJ, Hijri M, Sylvestre M

PloS one2015Senior author

DOI: 10.1371/journal.pone.0126033 PMID: 25970559

05

Prospects for using combined engineered bacterial enzymes and plant systems to rhizoremediate polychlorinated biphenyls.

Sylvestre M

Environmental microbiology2013First author

DOI: 10.1111/1462-2920.12007 PMID: 23106850

06

Plant exudates promote PCB degradation by a rhodococcal rhizobacteria.

Toussaint JP, Pham TT, Barriault D, Sylvestre M

Applied microbiology and biotechnology2012Senior author

DOI: 10.1007/s00253-011-3824-z PMID: 22202970

07

Remarkable ability of Pandoraea pnomenusa B356 biphenyl dioxygenase to metabolize simple flavonoids.

Pham TT, Tu Y, Sylvestre M

Applied and environmental microbiology2012Senior author

DOI: 10.1128/aem.00225-12 PMID: 22427498

08

Metabolism of chlorobiphenyls by a variant biphenyl dioxygenase exhibiting enhanced activity toward dibenzofuran.

Viger JF, Mohammadi M, Barriault D, Sylvestre M

Biochemical and biophysical research communications2012Senior author

DOI: 10.1016/j.bbrc.2012.02.029 PMID: 22342725

09

Retuning Rieske-type oxygenases to expand substrate range.

Mohammadi M, Viger JF, Kumar P, Barriault D, Bolin JT, Sylvestre M

The Journal of biological chemistry2011Senior author

DOI: 10.1074/jbc.m111.255174 PMID: 21653696

10

Transgenic plants to improve rhizoremediation of polychlorinated biphenyls (PCBs).

Sylvestre M, Macek T, Mackova M

Current opinion in biotechnology2009First author

DOI: 10.1016/j.copbio.2009.01.006 PMID: 19250817

Remodeling Rieske-type bacterial dioxygenases to change catalytic properties

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Sylvestre, Michel

$130,000

Biochemical, genetics and molecular biology of the bacterial biphenyl catabolic pathway enzymes

Principal investigatorNSERC2007Discovery Grants Program - Individual

Principal investigators: Sylvestre, Michel

$225,000

Plant chemicals to promote rhizoremediation of POP-contaminated brownfields

Principal investigatorNSERC2007Strategic Projects Supplemental Competition

Principal investigators: Sylvestre, Michel

$170,000

Request for a refrigerated centrifuge

Principal investigatorNSERC2006Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Sylvestre, Michel

$38,540

Magnetotactic phage-based microrobotic systems for the detection of live bacteria

Co-investigatorNSERC2005Strategic Projects - Group

Principal investigators: Martel, Sylvain

$500,500

Request for a microplate reader

Principal investigatorNSERC2005Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Sylvestre, Michel

$50,500

Biochemical, genetics and molecular biology of the bacterial bipehnyl catabolic pathway

Principal investigatorNSERC2002Discovery Grants Program - Individual

Principal investigators: Sylvestre, Michel

$207,800

Enzymes and plants engineering to phytoremediate priority pollutants.

Principal investigatorNSERC2002Strategic Projects - Group

Principal investigators: Sylvestre, Michel

$609,370

Request for a GC-ECD

Principal investigatorNSERC2002Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Sylvestre, Michel

$30,218

Purchase of a triple quadrupole mass spectrometer

Co-investigatorNSERC2000Research Tools and Instruments - Category 3 (>$325,000)

Principal investigators: Lépine, François

$137,000

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

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Applying for

Paper to mention

Subject: Prospective PhD student: Environmental biotechnologies Dear Professor Sylvestre, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Engineering Burkholderia xenovorans LB400 BphA through Site-Directed Mutagenesis at Position 283." (2020), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]