David Rosenblatt, McGill University

Research

Cobalamin Folate Genetics Homocysteine Methylmalonic Acid Vitamin B12

Latest papers

Expert Perspectives on Diagnosis and Management of Vitamin B12 Deficiency in Adults.
Advances in nutrition (Bethesda, Md.) · 2026
Differential utilization of vitamin B12-dependent and independent pathways for propionate metabolism across human cells.
The Journal of biological chemistry · 2024
The emerging role of the mitochondrial fatty-acid synthase (mtFASII) in the regulation of energy metabolism.
Biochimica et biophysica acta. Molecular and cell biology of lipids · 2019

All 5 publications

Latest funding

Next generation sequencing for the discovery of inborn errors of cobalamin metabolism
CIHR · 2016 · Nominated PI
$229,351
Search for non-coding mutations in patients with cblC and mut inborn errors of cobalamin metabolism
CIHR · 2013 · Supervisor
$17,500
Inborn errors of cobalamin and folate metabolism
CIHR · 2009 · Nominated PI
$979,000

All 4 grants and awards

5 publications.

01

Expert Perspectives on Diagnosis and Management of Vitamin B12 Deficiency in Adults.

Guéant JL, Alpers DH, Allen LH, Andres E, Devlin AM, Green A, Green R, Guéant Rodriguez RM, Hannibal L, Harrington D, Mason JB, McCaddon A, Miller JW, Murphy M, Nexo E, McNulty H, Owen JP, Quadros E, Rosenblatt D, Refsum H, Rietsema W, Stabler S, Ward M, Yajnik C, Finkelstein JL

Advances in nutrition (Bethesda, Md.)2026

DOI: 10.1016/j.advnut.2026.100726 PMID: 42641763

02

Differential utilization of vitamin B12-dependent and independent pathways for propionate metabolism across human cells.

Gouda H, Ji Y, Rath S, Watkins D, Rosenblatt D, Mootha V, Jones JW, Banerjee R

The Journal of biological chemistry2024

DOI: 10.1016/j.jbc.2024.107662 PMID: 39128713

03

The emerging role of the mitochondrial fatty-acid synthase (mtFASII) in the regulation of energy metabolism.

Wehbe Z, Behringer S, Alatibi K, Watkins D, Rosenblatt D, Spiekerkoetter U, Tucci S

Biochimica et biophysica acta. Molecular and cell biology of lipids2019

DOI: 10.1016/j.bbalip.2019.07.012 PMID: 31376476

04

Osteonecrosis of the femoral head: genetic basis.

Wang T, Azeddine B, Mah W, Harvey EJ, Rosenblatt D, Séguin C

International orthopaedics2019

DOI: 10.1007/s00264-018-4172-8 PMID: 30328481

05

Reporting results from whole-genome and whole-exome sequencing in clinical practice: a proposal for Canada?

Zawati MH, Parry D, Thorogood A, Nguyen MT, Boycott KM, Rosenblatt D, Knoppers BM

Journal of medical genetics2014

DOI: 10.1136/jmedgenet-2013-101934 PMID: 24078715

Next generation sequencing for the discovery of inborn errors of cobalamin metabolism

Nominated PICIHR2016Project Grant

Principal investigators: Rosenblatt, David S

Keywords: Cobalamin; Folate; Genetics; Homocysteine; Methylmalonic Acid; Vitamin B12

$229,351

Search for non-coding mutations in patients with cblC and mut inborn errors of cobalamin metabolism

SupervisorCIHR2013Master's Award: Canada Graduate Scholarships

Principal investigators: Brebner, Alison

Keywords: Human Genetics; Metabolic Disease; Mutation Analysis; Non-Coding Mutations; Patient-Focused Research; Pcr; Sequencing; Vitamin B12

$17,500

Inborn errors of cobalamin and folate metabolism

Nominated PICIHR2009Operating Grant

Principal investigators: Rosenblatt, David S

Keywords: Cobalamin; Folate; Homocysteine; Inborn Errors Of Metabolism; Methylmalonic Acid

$979,000

Vitamin B12 in Health and Disease

Nominated PICIHR2008Emerging Team Grant: From Genes to Proteins, Cells, Tissues and Patients - LOI

Principal investigators: Rosenblatt, David S

Keywords: Animal Models; Inborn Errors Of Metabolism; Protein Structure And Function; Small Molecule Screening; Vitamin B12

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Subject: Prospective PhD student: Cobalamin Dear Professor Rosenblatt, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Expert Perspectives on Diagnosis and Management of Vitamin B12 Deficiency in Adults." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]