Faculty profile

Jacques Archambault

ResearcherMicrobiology and ImmunologyMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Jacques Archambault

Researcher

Microbiology and Immunology

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
No publications since 2019.
Principal investigator on 4 research grants (4 CIHR), most recently in 2019.
Supervisor on 1 trainee award (1 CIHR), most recently in 2008.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Cell Biology Dna Replication Helicase Human Papillomavirus Molecular Biology Proteomic Virology Replication Stress

Latest papers

Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBPβ in the regulation of the viral early promoter.
Scientific reports · 2019 · senior author
Interaction of the Human Papillomavirus E1 Helicase with UAF1-USP1 Promotes Unidirectional Theta Replication of Viral Genomes.
mBio · 2019 · senior author
Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.
Cancer discovery · 2018

All 30 publications

Latest funding

Host factors involved in human papillomavirus (HPV) genome replication
CIHR · 2019 · Nominated PI
$860,626
Montreal International DNA Tumour Virus Meeting 2020
CIHR · 2019 · Co-investigator
$10,000
Host factors involved in human papillomavirus (HPV) genome replication
CIHR · 2018 · Nominated PI
$100,000

All 8 grants and awards

30 publications.

Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBPβ in the regulation of the viral early promoter.

Alvarez J, Gagnon D, Coutlée F, Archambault J

Scientific reports2019Senior author

DOI: 10.1038/s41598-019-41102-7 PMID: 30911096

Interaction of the Human Papillomavirus E1 Helicase with UAF1-USP1 Promotes Unidirectional Theta Replication of Viral Genomes.

Orav M, Gagnon D, Archambault J

mBio2019Senior author

DOI: 10.1128/mbio.00152-19 PMID: 30890612

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.

Eckhardt M, Zhang W, Gross AM, Von Dollen J, Johnson JR, Franks-Skiba KE, Swaney DL, Johnson TL, Jang GM, Shah PS, Brand TM, Archambault J, Kreisberg JF, Grandis JR, Ideker T, Krogan NJ

Cancer discovery2018

DOI: 10.1158/2159-8290.cd-17-1018 PMID: 30209081

Naturally Occurring Variations Modulate the Activity of the HPV33 Early Promoter and its Affinity for the E2 Transcription Factor.

Alvarez J, Gagnon D, Coutlée F, Archambault J

Scientific reports2018Senior author

DOI: 10.1038/s41598-018-33243-y PMID: 30301935

Isolation of a monoclonal antibody that recognizes the origin binding domain of JCV, but not SV40, large T-antigen.

Grubman SA, Shin J, Phelan PJ, Gong A, Can H, Dilworth R, Kini SK, Gagnon D, Archambault J, Meinke G, Bohm A, Jefferson DM, Bullock PA

Virology2016

DOI: 10.1016/j.virol.2016.07.006 PMID: 27433780

Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms.

El-Hachem N, Grossmann P, Blanchet-Cohen A, Bateman AR, Bouchard N, Archambault J, Aerts HJ, Haibe-Kains B

Environmental health perspectives2016

DOI: 10.1289/ehp.1409157 PMID: 26173225

Requirement for the E1 Helicase C-Terminal Domain in Papillomavirus DNA Replication In Vivo.

Bergvall M, Gagnon D, Titolo S, Lehoux M, D'Abramo CM, Melendy T, Archambault J

Journal of virology2016Senior author

DOI: 10.1128/jvi.03127-15 PMID: 26739052

Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.

Meinke G, Phelan PJ, Shin J, Gagnon D, Archambault J, Bohm A, Bullock PA

PLoS pathogens2016

DOI: 10.1371/journal.ppat.1005362 PMID: 26735515

Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication.

Gagnon D, Lehoux M, Archambault J

Journal of virology2015Senior author

DOI: 10.1128/jvi.00560-15 PMID: 25833051

A quantitative and high-throughput assay of human papillomavirus DNA replication.

Gagnon D, Fradet-Turcotte A, Archambault J

Methods in molecular biology (Clifton, N.J.)2015Senior author

DOI: 10.1007/978-1-4939-2013-6_23 PMID: 25348316

Host factors involved in human papillomavirus (HPV) genome replication

Nominated PICIHR2019Project Grant

Principal investigators: Archambault, Jacques

Keywords: Cell Biology; Dna Replication; Helicase; Human Papillomavirus; Molecular Biology; Proteomic; Replication Stress; Virology

$860,626

Montreal International DNA Tumour Virus Meeting 2020

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Teodoro, Jose G

Keywords: Adenovirus; Cancer; Conference; Hpv; Papillomavirus; Virology

$10,000

Host factors involved in human papillomavirus (HPV) genome replication

Nominated PICIHR2018Project Grant - Priority Announcement: Infection and Immunity

Principal investigators: Archambault, Jacques

Keywords: Biochemistry; Biomedical; Cell Biology; Dna Replication; Helicase; Human Papillomavirus; Molecular Biology; Proteomic; Virology

$100,000

Montreal International DNA Tumour Virus Meeting 2016

Co-investigatorCIHR2015Planning and Dissemination Grant - Institute Community Support

Principal investigators: Teodoro, Jose G

Keywords: Adenovirus; Cancer; Cervical Cancer; Dna Tumour Viruses; Herpesvirus; Hpv; Meeting; Polyomavirus; Vaccines; Virology

$10,000

Host factors involved in polyomavirus genome replication

Nominated PICIHR2012Operating Grant

Principal investigators: Archambault, Jacques

Keywords: Dna Replication; Helicase; Inhibitors; Molecular Biology; Peptide; Polyomavirus; Proteomics; Virology

$692,094

Montreal DNA Tumour Virus Meeting 2012

Co-investigatorCIHR2011Dissemination Events - Priority Announcement: Cancer Research

Principal investigators: Branton, Philip E

Keywords: Adenovirus; Cancer; Dna Tumour Viruses; Papillomavirus; Polyomavirus

$18,280

CIHR Team/Emerging Team in Single Molecule Studies on Viral Genome-replication Machinery, Inhibitors and Associated Resistance

Principal investigatorCIHR2009Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI

Principal investigators: Cosa, Gonzalo; Archambault, Jacques; Götte, Matthias

Keywords: Drug Resistance; Polymerase Inhibitors; Polymerase Mechanism; Protein Conformational Dynamics; Single Molecule Biophysics; Viral Dna And Rna Synthesis

Caractérisation de la fonction de la protéine cellulaire p80 dans la pathogenèse du virus du papillome humain

SupervisorCIHR2008Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Lehoux, Michaël

Keywords: Anémie De Fanconi; Culture Cellulaire; Dommages À L'Adn; Hélicase E1; Interactions Protéiques; Protéomique; Réplication De L'Adn; Ubiquitination; Virus Du Papillome Humain

$105,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jacques Archambault

Research

Latest papers

Latest funding

Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBP&#x3b2; in the regulation of the viral early promoter.

Interaction of the Human Papillomavirus E1 Helicase with UAF1-USP1 Promotes Unidirectional Theta Replication of Viral Genomes.

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.

Naturally Occurring Variations Modulate the Activity of the HPV33 Early Promoter and its Affinity for the E2 Transcription Factor.

Isolation of a monoclonal antibody that recognizes the origin binding domain of JCV, but not SV40, large T-antigen.

Characterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms.

Requirement for the E1 Helicase C-Terminal Domain in Papillomavirus DNA Replication In Vivo.

Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.

Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication.

A quantitative and high-throughput assay of human papillomavirus DNA replication.

Characterization of an HPV33 natural variant with enhanced transcriptional activity suggests a role for C/EBPβ in the regulation of the viral early promoter.