This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.
bioRxiv : the preprint server for biology · 2024
Latest funding
- $1,178,100
Regulation of ISG15-mediated innate immunity by coronaviral papain-like proteases
CIHR · 2025 · Co-investigator
- $994,500
Wildfire smoke inhibition of CFTR: mechanisms and mitigation
CIHR · 2024 · Nominated PI
- $90,000
The effect of air pollutants on the function of respiratory mucosal barriers
NSERC · 2023 · Co-investigator
1 publications.
Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.
Valenzuela AR, Turner M, Markarian N, Lachance-Brais C, Hanrahan J, Vali H, Vidal S, Mongeau L
Regulation of ISG15-mediated innate immunity by coronaviral papain-like proteases
Principal investigators: LIU, GUANQUN
Keywords: Antiviral Innate Immunity; Coronavirus; Interferon-Stimulated Gene; Isg15; Papain-Like Protease; Post-Translational Modifications; Sars-Cov-2; Virology; Virus-Host Interaction
Wildfire smoke inhibition of CFTR: mechanisms and mitigation
Principal investigators: Hanrahan, John W
Keywords: Acquired Cftr Deficiency; Cftr (Cystic Fibrosis Transmembrane Conductance Regulator); Copd Exacerbations; Redox Balance; Wildfire Smoke
The effect of air pollutants on the function of respiratory mucosal barriers
Principal investigators: Wagner, Caroline CE
Keywords: microfluidic; mucus; organ-on-chip; pollution; respiratory infection; viruses
Smoke effects on cell function and role in COPD
Principal investigators: Hanrahan, John W
Keywords: Acquired Cftr Deficiency; Cftr (Cystic Fibrosis Transmembrane Conductance Regulator); Copd; Redox Balance; Smoke
DIY airway renovations for healthy lungs
Principal investigators: Hanrahan, John
Keywords: airway cell biology functionalized nanostructures therapeutic development epithelial physiology chronic lung diseases cystic fibrosis mucus biophysics nano-material toxicology
DIY airway renovations for healthy lungs
Principal investigators: Hanrahan, John
Keywords: airway cell biology; functionalized nanostructures; therapeutic development; epithelial physiology; chronic lung diseases; cystic fibrosis; mucus biophysics; nano-material toxicology
Pharmacological chaperones that bind F508del-CFTR and their mechanisms of action
Principal investigators: Hanrahan, John W
Keywords: Cystic Fibrosis; Er Chaperones; Er Regulation; Human Primary Bronchial Epithelial Cells; Mechanisms Of Action; Medicinal Compound Synergy; Pharmacological Chaperones; Protein Trafficking Disease; Protein-Protein Interactions; Sites Of Action
Pharmacological chaperones for F508del-CFTR and their mechanisms of action.
Principal investigators: Hanrahan, John W
Keywords: Bronchial Epithelial Cells; Cystic Fibrosis; Drug Synergy; Endoplasmc Reticulum; Ion Channels; Mechanism Of Action; Pharmacological Chaperones; Protein Interactions; Protein Trafficking Diseases; Translational Research
Induced pluripotent stem cells for identification of novel drug combinations targeting cystic fibrosis lung and liver disease
Principal investigators: Hanrahan, John W
Keywords: Cystic Fibrosis; Drug Screens; Gene Correction; In Vitro Differentiation; Liver Cells; Lung Development; Stem Cells; Trafficking Mutations; Transgenic Reporters
CFTR modulators as a potential new therapeutic paradigm to treat individuals with COPD
Principal investigators: Hanrahan, John W
Keywords: Cftr; Cftr Modulators; Cigarette Smoke Extract; Copd; Novel Copd Drug Development; Primary Human Epithelial Cells
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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