Simon Wing

Advancing POP inhibitors as potential Parkinson's disease therapeutics

Principal investigators: Moitessier, Nicolas R

Keywords: Alpha-Synuclein Aggregation; Disease Modifying Therapy; Parkinson'S Disease; Therapeutics

Training platform in diabetes, obesity and cardiometabolic health

Principal investigators: Tchernof, André; Ball, Geoff D; Blondin, Denis; Brunt, Keith R; Colquhoun, Heather; Doucette, Christine A; Forhan, Mary A; McGavock, Jonathan M; Parry, Monica J; Screaton, Robert A; Sénéchal, Martin; Wei, Xiaolin; Wing, Simon S

Keywords: Cardiometabolic Health; Diabetes; Edi; Indigenous; Mentoring; Obesity; Patient Partner; Patient-Oriented Research; Training; Transdisciplinary

Cognitive decline in type 2 diabetes (DiCog Study)

Principal investigators: Morais, José A; Rahme, Elham; Rosa-Neto, Pedro; Spaic, Tamara; Theberge, Jean

Keywords: Alzheimer Disease Pathology; Cerebrovascular Disease; Cognitive Decline; Cohort Study; Hyperglycemia; Machine Learning; Mild Cognitive Impairment; Neuronally Derived Plasma Extracellular Vesicles; Type 2 Diabetes; Vascular Complications

USP19 in metabolism - mechanisms and translation

Principal investigators: Wing, Simon S

Keywords: Deubiquitinating Enzymes; Diabetes; Muscle Wasting; Obesity; Ubiquitin

Canadian Sepsis Research Network: Improving CareBefore, During and After Sepsis

Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Henry, Bonnie J; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Ansermino, John M; Barrett, Kali A; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan

Keywords: Biomarkers; Diabetes; Health Economics; Health Literacy; Health Services; Immune Endotypes; Knowledge Transfer; Population Health; Precision Medicine; Sepsis

Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis.

Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Schwartz, Brian; Ansermino, John M; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Loubani, Osama; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan

Keywords: Biomarkers; Diabetes And Obesity; Endotypes; Health Economics; Health Literacy; Health Services; Knowledge Transfer; Population Health; Precision Medicine; Sepsis

Unraveling the mechanisms underlying of bed rest-induced muscle atrophy and of an exercise countermeasure

Principal investigators: Morais, José A

Keywords: Autophagy; Bed Rest; Deuterated Water Method Of Protein Kinetics; Inactivity; Mitochondrial Function; Mtor Signaling Pathway; Muscle Fiber Typing; Musculoskeletal Unloading; Osteocalcin; Ubiquitin-Proteosome Pathway

Role of the Ubiquitin System in Spermatogenesis

Principal investigators: Wing, Simon

Whole-body and muscle myofibrillar protein degradation in response to insulin: a new non-invasive technique for use in elderly and cachectic patients

Principal investigators: Theal, Rebecca M

Keywords: 3-Methylhistidine; Insulin; Protein Breakdown; Skeletal Muscle Atrophy; Ubiquitin Proteasome System

Role of the Ubiquitin System in Sperm Development and Function

Principal investigators: Wing, Simon S

Keywords: Gonadal Development; Infertility; Molecular Biology; Protein Metabolism; Protein Purification; Proteolysis; Sperm Motility