Stéphane Laporte

Functional and structural understanding of angiotensin II type 1 receptor biased signaling.

Principal investigators: Laporte, Stéphane A; Leduc, Richard

Keywords: Angiotensin Ii Type 1 Receptor; Cardiac Diseases; Cell Signaling; Functional Selectivity; G Protein-Coupled Receptor (Gpcr); Peptide Chemistry; Protein Structure

20th Joint meeting of the Great Lakes GPCR Retreat and the Club des récepteurs à sept domaines transmembranaires du Québec

Principal investigators: Gendron, Louis

Keywords: Bias Signaling; Endocytosis; Functional Selectivity; G Protein-Coupled Receptors; Pharmacology; Protein Trafficking; Signaling; Structure Biology

Immunological consequences of inhaled cannabis and selected cannabinoids

Principal investigators: Baglole, Carolyn; Jensen, Dennis; Olivier, Martin

Keywords: Cannabinoid; Cannabis; Immune Cells; Lung; Marijuana

Understanding the allosteric and functional selectivity regulation of the Prostaglandin F2 receptor.

Principal investigators: Laporte, Stéphane A

Keywords: Bret/Fret; Crispr/Cas9; Gpcr; Molecular Pharmacology; Myometrial Cells; Pre-Term Birth; Prostaglandin F2 Alpha Receptor; Small Molecules Therapeutics; Structure Function; Tocolytics

Targeted Therapies for Lymphangioleiomyomatosis

Principal investigators: Kristof, Arnold S

Keywords: Drug Discovery; Estrogen; G-Protein Coupled Receptor; Interstitial Lung Disease; Lymphangioleiomyomatosis; Metastasis; Rare Lung Diseases; Respiratory Failure; Tuberous Sclerosis Complex; Urotensin

Targeted Therapies for Lymphangioleiomyomatosis

Principal investigators: Kristof, Arnold S

Keywords: G-Protein Coupled Receptor; Lymphangioleiomyomatosis; Metastasis; Neoplasm; Neural Crest; Tuberous Sclerosis Complex

Biased, Allosteric Regulation of Angiotensin II type 1 receptor Signalling and Trafficking

Principal investigators: Laporte, Stéphane A

Keywords: Allostery; Angiotesin Ii Type 1 Receptor; Arrestin; Biased Signalling; Cardiovascular Therapy; Drug Discovery; Gpcr; Trafficking

Allosteric Regulation and Biased Signaling of Prostaglandin F2alpha receptors.

Principal investigators: Laporte, Stéphane A

Keywords: Allosteric And Biased Signaling; Cancer; Drug Development; G Protein-Coupled Receptors; Molecular Pharmacoloy; Pre-Term Delivery; Prostaglandin

Mathematics of Information Technology and Complex Systems/Les mathématiques des technologies de l'information et des systèmes complexes

Principal investigators: Gupta, Arvind

Regulation of Angiotensin Type I Receptor Internalization by Endocytic Complexes and Signaling Effectors in Clathrin-Coated Vesicles

Principal investigators: Zimmerman, Brandon

Keywords: Angiotensin Type I Receptor; Beta2-Adaptin; C-Src; Co-Immunoprecipitation; Confocal Microscopy; Epidermal Growth Factor Receptor; Green Fluorescent Protein; Internalization; Mass Spectrometry; Phosphorylation