Timothy Kennedy

Synthetic Synapses: Engineering Next-Generation Biomimetic Electrodes for Enhanced Neural Integration

Principal investigators: Kennedy, Timothy E

Keywords: Heparan Sulfate; Hspg; Molecular Biomimicry; Neural Biocompatibility; Neural Prosthetic; Polyelectrolyte; Synaptogenesis; Synthetic Synapse

Investigating a role for netrin-1/DCC signaling in excitatory homeostatic synaptic upscaling

Principal investigators: Feighan, Kira M

Keywords: Alzheimer'S Disease; Deleted In Colorectal Cancer; Electrophysiology; Homeostatic Synaptic Scaling; Metaplasticity; Netrin-1; Neurodegeneration; Parkinson'S Disease; Synaptic Maintenance; Synaptic Plasticity

Charging into the Future (CITF): Training in Polyelectrolyte Biosystems for Tomorrowès Health Challenges

Principal investigators: Kizhakkedathu, Jayachandran N

Keywords: biomaterials; biomedical applications; drug delivery; material innovation for biology; nanomedicinie; polycations and polyanions; polyelectrolytes; protein binding; theoretical chemistry; therapeutics

Investigating a New Molecular Mechanism Underlying Structural and Functional Synaptic Plasticity

Principal investigators: Kennedy, Timothy E

Keywords: Cell Biology; Dcc; Dendritic Spine; Electrophysiology; Genetically Modified Mice; Hippocampus; Long-Term Potentiation; Netrin-1; Synapse; Synaptic Plasticity

Axon Guidance by Extracellular Gradients: Mechanisms Regulating Neural Circuit Formation

Principal investigators: Kennedy, Timothy E

Keywords: Axon Guidance; Cell Migration; Chemotropism; Dcc; Embryonic Development; Glycosaminoglycan; Gradient; Growth Cone; Microcontact Printing; Netrin

Unraveling the molecular basis of novel forms of hypomyelinating leukodystrophies

Principal investigators: Bernard, Geneviève

Keywords: Eprs1-Related Leukodystrophy; Gene Discovery; Hypomyelinating Leukodystrophies; Induced Pluripotent Stem Cells; Myelination Studies; Next Generation Sequencing; Oligodendrocyte Progenitor Cells / Oligodendrocytes; Polr3-Related Leukodystrophy; Proteomics; Rare Diseases

A New Mechanism Regulating Synapse Function in the Brain

Principal investigators: Kennedy, Timothy E

Keywords: Acetylcholine; Cell Biology; Electrophysiology; Genetically Modified Mice; Hippocampus; Netrin; Patch Clamp; Plasticity; Synapse; Synaptogenesis

Bio-integrated fully implantable peripheral nerve electrode for functional upper limb prostheses

Principal investigators: Kennedy, Timothy

Bio-integrated fully implantable peripheral nerve electrode for functional upper limb prostheses

Principal investigators: Kennedy, Timothy E; Lennox, Robert B

Keywords: Biomedical Device; Biomedical Engineering; Biomimetic Synapse; Enhanced Biocompatibility; Neuro-Compatible Extracellular Matrix; Peripheral Nerve Injury; Synthetic Extracellular Matrix; Synthetic Synapse; Upper Limb Prosthetic

Electrophysiology system to study novel regulators of synaptogenesis

Principal investigators: Ruthazer, Edward