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Research
Latest papers
Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer’s disease mouse model
bioRxiv (Cold Spring Harbor Laboratory) · 2024
Latest funding
- $948,600
Chromatin control of cell fate and epigenome formation in human epiblast and trophoblast
CIHR · 2025 · Nominated PI
- $97,880
A histology platform to visualize cells, tissues and organs across living systems
NSERC · 2024 · Co-investigator
- $100,000
Role of ZMYM2 in guiding de novo methylation in mammalian development
CIHR · 2022 · Nominated PI
1 publications.
Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer’s disease mouse model
Penalva YCM, Paschkowsky S, Yang J, Recinto SJ, Cinkorpumin J, Hernandez MR, Xiao B, Nitu A, Wu HY-L, Munter HM
Chromatin control of cell fate and epigenome formation in human epiblast and trophoblast
Principal investigators: Pastor, William A
Keywords: Cell Fate; Chromatin; Dna Methylation; Embryonic Development; Epigenetics; Placental Development; Proteomics; Rna-Sequencing
A histology platform to visualize cells, tissues and organs across living systems
Principal investigators: Cockburn, Katherine
Keywords: Animal models; Biomedical engineering; Cell biology; Cell morphology; Gene expression; Histology; Materials science; Tissue architecture; Tissue sectioning
Role of ZMYM2 in guiding de novo methylation in mammalian development
Principal investigators: Pastor, William A; Bouchard, Maxime L
Keywords: Developmental Biology; Dna Methylation; Epigenetics; Germ Cells; Heterochromatin; Transposable Elements
Establishing the role of ZMYM2 in mediating transcriptional silencing and DNA methylation during mammalian embryonic development
Principal investigators: Pastor, William A
Keywords: Developmental Biology; Dna Methylation; Epigenetics; Germ Cells; Heterochromatin; Transposable Elements
Understanding cellular heterogeneity in the oviductal epithelium and tubo-ovarian cancer susceptibility.
Principal investigators: Yamanaka, Yojiro
Keywords: Cellular Heterogeneity; Crispr; Mouse Model; Mullerian Duct; Organoids; Oviduct/Fallopian Tube; Reproduction
Transcriptional Regulation of Human Trophoblast Development
Principal investigators: Pastor, William A
Keywords: Placenta; Transcription Factors; Transcriptional Regulators; Trophoblast
Regulation of 5-methylcytosine upon the transition from naive to primed pluripotency
Principal investigators: Pastor, William
Regulation of 5-methylcytosine upon the transition from naive to primed pluripotency
Principal investigators: Pastor, William
Determining how inherited modifications of DNA control cell division and the correct development of the placenta
Principal investigators: Pastor, William
Keywords: Placenta, DNA methylation, Imprinting (epigenetic), Epigenetics, Reproductive Medicine, Gene expression, Developmental biology
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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