Youla Tsantrizos

Geranylgeranylation Inhibitors as Novel Therapeutics for the Treatment of TP53 Wild Type and Mutated Acute Myeloid Leukemia (AML)

Principal investigators: Tsantrizos, Youla S

Keywords: Acute Myeloid Leukemia; Antitumor Agents For Blood Cancers; Drug Discovery; Stimulations Of The Immune System To Cancer Chemotherapy

Multi-mode Microplate Reader

Principal investigators: Cosa, Gonzalo

Molecular Tools that Block Maturation of the Nuclear Lamin A, Leading to Decrease in Proliferation and Metastasis of Pancreatic Ductal Adenocarcinoma and Colorectal Cancer

Principal investigators: Tsantrizos, Youla S

Keywords: Anti-Tumor Agents For Colorectal Cancer; Anti-Tumor Agents For Pancreatic Ductal Adenocarcinoma; Drug Discovery

Engineering Phosphorus-Containing Molecules as Leads for Medicinal Chemistry and as Tools for Asymmetric Synthesis

Principal investigators: Tsantrizos, Youla

NMR Systems Upgrade for a Sustainable New Era

Principal investigators: Tsantrizos, Youla

Validation of the human geranylgeranyl pyrophosphate synthase (hGGPPS) as a therapeutic target for cancer chemotherapy and design of pre-clinical candidates for the treatment of multiple myeloma

Principal investigators: Tsantrizos, Youla S

Keywords: Antitumor Agents; Drug Discovery; Validation Of A New Therapeutic Target

Chemical Biology and Early Stages of Drug Discovery

Principal investigators: Tsantrizos, Youla

Benchmark proprietary pyridine- and thienopyrimidine-based bisphosphonates against the standard of care drug Zometa® in the treatment of multiple myeloma

Principal investigators: Tsantrizos, Youla S

Keywords: Farnesyl Pyrophosphate Inhibitors; Multiple Myeloma

Development of a Transgenic Mouse Model and Testing Platform of Multiple Myeloma Bone Disease

Principal investigators: Sebag, Michael

Keywords: Bisphosphonates; Bone Disease; Multiple Myeloma; Novel Therapies; Osteoblasts; Osteoclasts

Validation of the human farnesyl pyrophosphate synthase (hFPPS) as a therapeutic target and design of pre-clinical candidates for the treatment of multiple myeloma and neurodegenerative diseases.

Principal investigators: Tsantrizos, Youla S

Keywords: Alzheimer'S; Drug Discovery; Farnesyl Pyrophosphate Synthase; Multiple Myeloma