This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Tension directs cancer cell migration over fiber alignment through energy minimization.
Biomaterials · 2024
Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA.
Cell reports · 2023
Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis.
eLife · 2022
Latest funding
- $35,000
Identification of a mechano-dependent alternative splicing profile predictive of metastatic potential
CIHR · 2025 · Supervisor
- $500,000
Canada Research Chair - Tier 2
CIHR · 2024 · Nominated PI
- $250,000
Creating a biomimetic 3D engineered model of the liver metastatic niche
SSHRC · 2023 · Principal investigator
9 publications.
Tension directs cancer cell migration over fiber alignment through energy minimization.
Zanotelli MR, Miller JP, Wang W, Ortiz I, Tahon E, Bordeleau F, Reinhart-King CA
Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA.
Wang W, Taufalele PV, Millet M, Homsy K, Smart K, Berestesky ED, Schunk CT, Rowe MM, Bordeleau F, Reinhart-King CA
Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis.
Schwager SC, Young KM, Hapach LA, Carlson CM, Mosier JA, McArdle TJ, Wang W, Schunk C, Jayathilake AL, Bates ME, Bordeleau F, Antonyak MA, Cerione RA, Reinhart-King CA
Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells.
Hapach LA, Carey SP, Schwager SC, Taufalele PV, Wang W, Mosier JA, Ortiz-Otero N, McArdle TJ, Goldblatt ZE, Lampi MC, Bordeleau F, Marshall JR, Richardson IM, Li J, King MR, Reinhart-King CA
Tissue transglutaminase 2 regulates tumor cell tensional homeostasis by increasing contractility.
Bordeleau F, Wang W, Simmons A, Antonyak MA, Cerione RA, Reinhart-King CA
Author Correction: Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making.
Zanotelli MR, Rahman-Zaman A, VanderBurgh JA, Taufalele PV, Jain A, Erickson D, Bordeleau F, Reinhart-King CA
Extent of Cell Confinement in Microtracks Affects Speed and Results in Differential Matrix Strains.
Mosier JA, Rahman-Zaman A, Zanotelli MR, VanderBurgh JA, Bordeleau F, Hoffman BD, Reinhart-King CA
Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making.
Zanotelli MR, Rahman-Zaman A, VanderBurgh JA, Taufalele PV, Jain A, Erickson D, Bordeleau F, Reinhart-King CA
Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology.
Millet M, Ben Messaoud R, Luthold C, Bordeleau F
Identification of a mechano-dependent alternative splicing profile predictive of metastatic potential
Principal investigators: Gouhier, Juliette
Keywords: Alternative Splicing; Breast Cancer; Extracellular Matrix Stiffness; Mcf10a; Mda-Mb-231; Metastatic Potential; Vivoanalysis
Canada Research Chair - Tier 2
Principal investigators: Bordeleau, François
Keywords: Crc
Creating a biomimetic 3D engineered model of the liver metastatic niche
Principal investigators: Bordeleau, François
Keywords: Tissue Engineering; Cell-Cell communication; Extracellular matrix; Microfluidics; Liver; Metastasis; Vascularization; Tissue mechanical properties; Mechanobiology; Tissue histology
Hepatic stellate cells as a driver of the pre-metastatic niche in uveal melanoma
Principal investigators: Bordeleau, François; Landreville, Solange
Keywords: Cell Contractility; Extracellular Vesicles; Hepatic Stellate Cells; Liver Metastasis; Matrix And Tissue Stiffness; Tissue Engineered Models; Uveal Melanoma
Toward elucidating the interplay between cell contractility state, mechanotransduction and alternative splicing during tumor progression
Principal investigators: Bordeleau, François
Keywords: Alternative Splicing; Cell Contractility; Cell Migration; Engineered Scaffolds; Focal Adhesion; Matrix And Tissue Stiffness; Mechanobiology
Canada Research Chairs - Tier 2
Principal investigators: Bordeleau, François
Keywords: Crc
The combined role of cellular force dynamics and extracellular matrix mechanical properties in driving angiogenesis
Principal investigators: Bordeleau, François
The combined role of cellular force dynamics and extracellular matrix mechanical properties in driving angiogenesis
Principal investigators: Bordeleau, François
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.