Research
Read how they describe their research on their Université Laval profile.
Latest papers
Endothelial microRNAs regulating the NF-κB pathway and cell adhesion molecules during inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018 · senior author
p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells.
Scientific reports · 2018
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.
Oncotarget · 2017 · senior author
Latest funding
- $240,000
Role of microRNAs in regulating endothelial cell functions
NSERC · 2011 · Principal investigator
- $270,000
Molecular mechanisms of cardiovascular diseases in chronic renal failure: probing molecular interactions in the vessel wall
CFI · 2008 · Co-investigator
23 publications.
Endothelial microRNAs regulating the NF-κB pathway and cell adhesion molecules during inflammation.
Zhong L, Simard MJ, Huot J
p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells.
Zhong L, Huot J, Simard MJ
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.
Corre I, Paris F, Huot J
p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription.
Zhong L, Simoneau B, Huot J, Simard MJ
Oxidative stress disassembles the p38/NPM/PP2A complex, which leads to modulation of nucleophosmin-mediated signaling to DNA damage response.
Guillonneau M, Paris F, Dutoit S, Estephan H, Bénéteau E, Huot J, Corre I
MicroRNA-196a promotes an oncogenic effect in head and neck cancer cells by suppressing annexin A1 and enhancing radioresistance.
Suh YE, Raulf N, Gäken J, Lawler K, Urbano TG, Bullenkamp J, Gobeil S, Huot J, Odell E, Tavassoli M
Development of a tridimensional microvascularized human skin substitute to study melanoma biology.
Gibot L, Galbraith T, Huot J, Auger FA
miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.
Pin AL, Houle F, Guillonneau M, Paquet ER, Simard MJ, Huot J
Regulation of endothelial permeability and transendothelial migration of cancer cells by tropomyosin-1 phosphorylation.
Simoneau B, Houle F, Huot J
Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression.
Pin AL, Houle F, Fournier P, Guillonneau M, Paquet ÉR, Simard MJ, Royal I, Huot J
Role of microRNAs in regulating endothelial cell functions
Principal investigators: Huot, Jacques
Molecular mechanisms of cardiovascular diseases in chronic renal failure: probing molecular interactions in the vessel wall
Principal investigators: Isenring, Paul
Keywords: cardiovascular diseases, chonic kidney diseases, vascular smooth muscle cell, endothelial cell dysfunction, protein-protein interactions, signaling pathways, ion-transport systems
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
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Profile data last refreshed on September 27, 2026 from the university directory, publication records and public research funding records.