Jacques Tremblay

Deciphering the role of MEF2 transcription factors in testis development and male sex differentiation

Principal investigators: Tremblay, Jacques J

Keywords: Cell Differentiation; Fertility; Gene Expression; Gene Knockout In Mice; Leydig Cells; Male Sex Differentiation; Puberty; Sertoli Cells; Testis Formation; Transcription Factors

Upgrade of a the CHUQ-UL Division of reproduction microscopy platfrom

Principal investigators: Elowe, Sabine

Keywords: spinning disk confocal; reproductive organs; cilia; mitosis

Cibles et mécanisme d'action du facteur de transcription COUP-TFII dans les cellules de Leydig

Principal investigators: Pierre, Kenley Joule

Keywords: Cellule De Leydig

Correction with the Prime editing technology of point mutations responsible for Duchenne Muscular Dystrophy.

Principal investigators: Tremblay, Jacques P

Keywords: Adeno Associated Virus; Crispr; Duchenne Muscular Dystrophy; Genome Editing; Hereditary Disease; Nucleotide Editing; Prime Editing

Probing the origins and crosstalk between the different Leydig cell populations in the mammalian gonad

Principal investigators: Tremblay, Jacques J.

Defining the role of GATA4 in steroidogenic cells and sex differentiation in males using novel mouse models

Principal investigators: Tremblay, Jacques J

Keywords: Cell Differentiation; Fertility; Gene Knockout In Mouse; Gene Regulation; Leydig Cells; Male Sex Differentiation; Puberty; Reproduction; Steroidogenesis; Testis

Development of a rapid and simple test to detect the COVID-19 variants that can be used in remote areas and developing countries.

Principal investigators: Tremblay, Jacques P

Keywords: Covid-19; Detection Test; Green Fluorescence; Lamp

Detection and differentiation of SARS-CoV-2 variants of concern using isothermal amplification and CRISPR effectors

Principal investigators: Lamothe, Gabriel

Keywords: Bioinformatics; Covid-19; Crispr/Cas12+Cas13; Diagnostic Tets; Inactivation, Detection, And Differentiation Of Variants; Loop-Mediated Isothermal Amplification (Lamp); Point Of Care Testing (Poct); Sars-Cov-2; Variants Of Concern; Variants Of Interest

Removal of the GAA repeat with the CRISPR/Cas9 system in Friedreich patient cells and in the YG8sR mouse model."

Principal investigators: Tremblay, Jacques P

Keywords: Crispr/Cas9; Friedreich Ataxia,; Gaa Repeat Deletion; Yg8sr

Deciphering the role of DCIR in HIV-1 pathogenesis

Principal investigators: Gilbert, Caroline

Keywords: Dcir; Dendritic Cells; Extracellular Vesicles; Hiv-1; Immune Responses; Lectin Type C; Nsg Mice; Pathogenesis; T Lymphocytes; Therapeutic Target