Faculty profile
Sébastien Hébert
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Latest funding
- $1,464,976
Rewilding Alzheimer's Research: Investigating the Role of Natural Immunity in Disease Progression and Therapeutic Efficacy
CIHR · 2026 · Nominated PI
- $1,150,180
Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
CIHR · 2021 · Nominated PI
- $192,000
Importance of non-canonical microRNAs in the mammalian brain
NSERC · 2020 · Principal investigator
Rewilding Alzheimer's Research: Investigating the Role of Natural Immunity in Disease Progression and Therapeutic Efficacy
Principal investigators: Hébert, Sébastien
Keywords: Alzheimer'S Disease; Amyloid-Beta; Animal Welfare; Behaviour; Imaging; Immunization; Microglia; Mouse Models; Rewilding; Tau
Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
Principal investigators: Hébert, Sébastien
Keywords: Cognition; Gene Therapy; Intrathecal; Microrna; Mouse; Neurodegenerative Diseases; Oligonucleotide; Pharmacokinetics; Primate; Toxicology
Importance of non-canonical microRNAs in the mammalian brain
Principal investigators: Hébert, Sébastien
Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
Principal investigators: Hébert, Sébastien
Keywords: Gene Silencing; Gene Therapy; Intrathecal; Microrna; Mouse; Non-Human Primate; Oligonucleotide; Pharmacodynamics; Pharmacokinetics; Toxicology
microRNA-132: from underlying mechanism of neurodegeneration to therapeutic application in Huntington's disease
Principal investigators: Hébert, Sébastien
Keywords: Huntington'S Disease; Microrna; Mouse Model; Post-Mortem Tissue
GWAS in AD: focus on microRNA
Principal investigators: Hébert, Sébastien
Keywords: Alzheimer'S Disease; Amyloid; Gwas; Microrna; Mouse Models; Snps; Tau
MicroRNA-15 dysregulation in sporadic Alzheimer's disease: testing the "multiple hit" hypothesis in neurodegenerative disorders
Principal investigators: Hébert, Sébastien
Keywords: Alzheimer'S Disease; Lentivirus; Microrna; Mouse Models; Neurodegeneration; Noncoding Rna; Posttranscriptional Gene Expression Regulation
MicroRNA loss-of-function tools to study neurodegeneration
Principal investigators: Hébert, Sébastien
Keywords: Alzheimer'S Disease; Lentivirus; Loss-Of-Function; Microrna; Mouse Models; Noncoding Rna
MicroARNS comme modulateurs de la pathologie Tau
Principal investigators: Hébert, Sébastien; Buee, Luc
Keywords: Alternative Splicing; Alzheimer'S Disease; Animal Models; Dicer; Phosphorylation; Tauopathies
Systematic investigation of microRNA function in developing neurons
Principal investigators: Hébert, Sébastien
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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