Ynuk Bosse

Sex and sex-hormones determine pulmonary morphological and single-nucleus transcriptomic responses in an animal model of sleep apnea.

Principal investigators: Joseph, Vincent

Keywords: Intermittent Hypoxia; Lung Morphology; Male And Female Mice; Ovariectomy - Orchiectomy; Single Cell/Nucleus Rna Sequencing; Sleep Apnea

Testosterone on airway hyperresponsiveness in asthma

Principal investigators: Bosse, Ynuk

Keywords: Airway Hyperresponsiveness; Allergen; Asthma; Inflammation; Lung Function; Sex; Sexual Dimorphism; Sexual Hormones; Smooth Muscle; Testosterone

PhysioLens: a novel technology to standardize and democratize respiratory research on lung tissue

Principal investigators: Bossé, Ynuk

The physiological role of airway smooth muscle

Principal investigators: Bossé, Ynuk

Refining preclinical tools in lung physiology to evaluate COVID-19-mediated deaths from respiratory failure_x000d_ _x000d_ _x000d_ _x000d_ _x000d_

Principal investigators: Bossé, Ynuk

Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema

Principal investigators: Morissette, Mathieu

Keywords: Clinical Samples; Emphysema; Immunology; Mouse Model; Ptpn6; Smoking

Airway smooth muscle tone on asthmatic airway hyperresponsiveness

Principal investigators: Bosse, Ynuk

Keywords: Airway Hyperresponsiveness; Airway Mechanics; Airway Smooth Muscle; Asthma; Bronchodilators; Inflammation; Lung Function; Multiple Biological Scales; Remodeling; Spasmogens

Capturing the in situ behavior of airway smooth muscle in human bronchi using an ex vivo system that simulates breathing maneuvers

Principal investigators: Bossé, Ynuk

Mechanical Properties Of Human Airway Smooth Muscle In Vitro And In Vivo: Normal Structure And Function And Abnormalities In Asthma

Principal investigators: Seow, Chun Y; Pare, Peter D

Keywords: Adaptation; Airway Smooth Muscle; Asthma; Bronchial Hyperresponsiveness; Length Tension Relationship; Smooth Muscle Plastiticy