Eric Samarut, Université de Montréal

Research

Genomics Epilepsy Functional Genomics Genetics Zebrafish

Latest papers

Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders.
iScience · 2024
A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish.
PloS one · 2019 · first author

All 5 publications

Latest funding

Peripheral and CNS inflammation and injury profiles in children with Tuberous Sclerosis Complex and their association with neurological disability and treatment with mTOR inhibitors: a multicentre, longitudinal study cohort.
CIHR · 2025 · Co-investigator
$1,453,500
Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics
CIHR · 2023 · Nominated PI
$30,000
Neuroinflammation as a biomarker for epilepsy and neuropsychiatric comorbidities among people with tuberous sclerosis complex: a prospective, multicentre study
CIHR · 2022 · Co-investigator
$726,750

All 7 grants and awards

5 publications.

01

Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders.

Lee JJ, Wang T, Wiggins K, Lu PN, Underwood C, Ochenkowska K, Samarut E, Pollard LM, Flanagan-Steet H, Steet R

iScience2024

DOI: 10.1016/j.isci.2024.109293 PMID: 38495824

02

A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies.

Nieoczym D, Marszalek-Grabska M, Szalak R, Kundap U, Kaczor AA, Wrobel TM, Kosheva N, Komar M, Abram M, Esguerra CV, Samarut E, Pieróg M, Jakubiec M, Kaminski K, Kukula-Koch W, Gawel K

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2024

DOI: 10.1016/j.biopha.2024.116234 PMID: 38325264

03

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish.

Samarut E, Chalopin D, Riché R, Allard M, Liao M, Drapeau P

PloS one2019First author

DOI: 10.1371/journal.pone.0216159 PMID: 31048868

04

The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos.

Dzieciolowska S, Larroque AL, Kranjec EA, Drapeau P, Samarut E

Scientific reports2017Senior author

DOI: 10.1038/srep40067 PMID: 28051181

05

Transcriptomic Analysis of Purified Embryonic Neural Stem Cells from Zebrafish Embryos Reveals Signaling Pathways Involved in Glycine-Dependent Neurogenesis.

Samarut E, Bekri A, Drapeau P

Frontiers in molecular neuroscience2016First author

DOI: 10.3389/fnmol.2016.00022 PMID: 27065799

Peripheral and CNS inflammation and injury profiles in children with Tuberous Sclerosis Complex and their association with neurological disability and treatment with mTOR inhibitors: a multicentre, longitudinal study cohort.

Co-investigatorCIHR2025Project Grant

Principal investigators: Keezer, Mark; House, Andrew A; Larochelle, Catherine; Major, Philippe; Nabavi Nouri, Maryam; Sham, Lauren

Keywords: Biomarkers; Epilepsy; Genetics; Immune System; Intellectual Disability; Tuberous Sclerosis Complex

$1,453,500

Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics

Nominated PICIHR2023PRIZE - Project Grant - PA: Maud Menten - Biomedical Research

Principal investigators: Samarut, Eric

Keywords: Genomics

$30,000

Neuroinflammation as a biomarker for epilepsy and neuropsychiatric comorbidities among people with tuberous sclerosis complex: a prospective, multicentre study

Co-investigatorCIHR2022Project Grant

Principal investigators: Keezer, Mark; House, Andrew A; Larochelle, Catherine; Major, Philippe

Keywords: Biomarkers; Epilepsy; Immune System; Inflammation; Tuberous Sclerosis Complex

$726,750

Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics

Nominated PICIHR2022Project Grant

Principal investigators: Samarut, Eric

Keywords: Epilepsy; Functional Genomics; Genetics; Zebrafish

$952,425

The role of GABA signaling in nervous system formation and homeostasis

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: SAMARUT, ERIC

$120,000

Non-invase high-throughput genotyping of zebrafish larvae (phase I)

Principal investigatorNSERC2021Idea to Innovation

Principal investigators: Samarut, Éric

$122,500

The role of GABA signaling in nervous system formation and homeostasis

Principal investigatorNSERC2021Discovery Launch Supplement

Principal investigators: SAMARUT, ERIC

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Pierre Drapeau

Neurosciences

3 shared papers, latest 2019

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Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Genomics Dear Professor Samarut, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]