This profile is built from public research funding records (CIHR, NSERC and SSHRC). We have not imported them from a Université de Montréal directory, so their publications, courses and email address may be missing. Find their university profile.
Research
Latest funding
- $849,150
Molecular mechanisms underlying high-affinity and isotype switched antibody responses
CIHR · 2023 · Nominated PI
- $845,326
Regulation of germinal center B cell function during antibody responses
CIHR · 2019 · Nominated PI
- $10,000
DNA deamination in adaptive and innate immunity: 20 years after the discovery of Activation induced deaminase
CIHR · 2019 · Nominated PI
Molecular mechanisms underlying high-affinity and isotype switched antibody responses
Principal investigators: Di Noia, Javier M
Keywords: Activation Induced Deaminase; Antibody Responses; B Cell Lymphoma; Class Switch Recombination; Dna Damage; Germinal Center; Mutagenesis; Proteomics; Somatic Hypermutation
Regulation of germinal center B cell function during antibody responses
Principal investigators: Di Noia, Javier M
Keywords: Antibody Response; B Cell Phyisiology; B Lymphocytes; Germinal Center; Immune Responses; Immunization; Signal Transduction
DNA deamination in adaptive and innate immunity: 20 years after the discovery of Activation induced deaminase
Principal investigators: Di Noia, Javier M
Keywords: Antibodies; Hematological Cancer; Immune Response; Immunological Memory; Mutation
Regulation and impact of productive AID targeting during antibody responses.
Principal investigators: Di Noia, Javier M
Keywords: Activation Induced Deaminase; Antibody Responses; Apobec; Class Switch Recombination; Germinal Center B Cells; Somatic Hypermutation
Coordinating DNA deamination, double strand break and repair to prevent genomic instability during antibody gene diversification.
Principal investigators: Di Noia, Javier M
Keywords: Activation Induced Deaminase; Chromosomal Translocations; Class Switch Recombination; Dna Double Strand Breaks; Genomic Instability; Non-Homologous End Joining; Somatic Hypermutation; Uracil Dna Glycosylase
Molecular mechanisms and function of AID-dependent antibody diversification
Principal investigators: Di Noia, Javier M
Keywords: Activation Induced Deaminase; Antibody Gene Diversification; Antibody Isotype Switching; Antibody Mediated Immune Response; Genetically Modified Mice; Lymphocyte B; Molecular Biology; Protein Stability; Subcellular Localization
CANADA RESEARCH CHAIRHOLDER - Tier 2 / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA - Niveau 2
Principal investigators: Di Noia, Javier M
Keywords: Crc
Identification and characterization of AID functional domains suppressing DNA damage and chromosomal translocations.
Principal investigators: Methot, Stephen P
Keywords: Affinity Maturation; Biochemistry; Cancer; Dna Repair; Enzyme Regulation; Genetic Diversification; Immunology; Immunoprecipitation; Lymphomas; Pcr
The evolution of cytidine deaminases capable of generating genetic diversity by editing nucleic acids
Principal investigators: DiNoia, Javier
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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