Faculty profile
Marc Drolet
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Research
Latest papers
R-Loop Detection in Bacteria.
Methods in molecular biology (Clifton, N.J.) · 2022 · senior author
R-loop-dependent replication and genomic instability in bacteria.
DNA repair · 2019 · first author
Detection of oriC-Independent Replication in Escherichia coli Cells.
Methods in molecular biology (Clifton, N.J.) · 2018 · senior author
Latest funding
- $96,000
Functions of bacterial type IA topoisomerases in the prevention of R-loop-dependent and -independent genomic instability.
NSERC · 2022 · Principal investigator
- $186,000
Bacterial type 1A topoisomerases in genome stability.
NSERC · 2016 · Principal investigator
- $200,000
Function of type1A topoisomerases in bacterial chromosome segregation
NSERC · 2010 · Principal investigator
6 publications.
R-Loop Detection in Bacteria.
Vlachos-Breton É, Drolet M
R-loop-dependent replication and genomic instability in bacteria.
Drolet M, Brochu J
Detection of oriC-Independent Replication in Escherichia coli Cells.
Martel M, Balleydier A, Brochu J, Drolet M
Mutations reducing replication from R-loops suppress the defects of growth, chromosome segregation and DNA supercoiling in cells lacking topoisomerase I and RNase HI activity.
Usongo V, Martel M, Balleydier A, Drolet M
Constitutive stable DNA replication in Escherichia coli cells lacking type 1A topoisomerase activity.
Martel M, Balleydier A, Sauriol A, Drolet M
Growth inhibition mediated by excess negative supercoiling: the interplay between transcription elongation, R-loop formation and DNA topology.
Drolet M
Functions of bacterial type IA topoisomerases in the prevention of R-loop-dependent and -independent genomic instability.
Principal investigators: Drolet, Marc
Keywords: topoisomerases; r-loops; dna supercoiling; dna replication; bacterial genetics; dna recombination; nucleotide excision repair; dna topology; chromosomes segregation; dna breaks
Bacterial type 1A topoisomerases in genome stability.
Principal investigators: Drolet, Marc
Function of type1A topoisomerases in bacterial chromosome segregation
Principal investigators: Drolet, Marc
Canadian Research Network on Bacterial Pathogens of swine
Principal investigators: Jacques, Mario
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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