Faculty profile
Marc Servant
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Research
Latest papers
Position of Src tyrosine kinases in the interaction between angiotensin II and endothelin in in vivo vascular protein synthesis.
Journal of hypertension · 2005
Latest funding
- $757,350
Regulation of innate antiviral defenses through Interleukin-17 receptor D (IL-17RD)
CIHR · 2020 · Nominated PI
- $738,226
Role of the deubiquitylating enzyme USP17 in colorectal cancer
CIHR · 2019 · Nominated PI
- $534,931
Characterization of novel effectors that contribute to the fine-tuning of the antiviral cellular response following virus infection
CIHR · 2015 · Nominated PI
1 publications.
Position of Src tyrosine kinases in the interaction between angiotensin II and endothelin in in vivo vascular protein synthesis.
Beaucage P, Iglarz M, Servant M, Touyz RM, Moreau P
Regulation of innate antiviral defenses through Interleukin-17 receptor D (IL-17RD)
Principal investigators: Servant, Marc
Keywords: Fine-Tuning Of The Antiviral Innate Immune Response; Ikk Complex; Il-17rd; Interferon Regulatory Factors (Irf) Transcription Factors; Nf-Kb Transcription Factor; Repressor Functions; Rig-I-Like Receptors; Rna Viruses; Tbk1; Type I/Iii Interferons
Role of the deubiquitylating enzyme USP17 in colorectal cancer
Principal investigators: Servant, Marc; Meloche, Sylvain
Keywords: Colorectal Cancer; Deubiquitylating Enzymes (Dubs); Mouse Xenograft Models; Oncogene; Proliferation And Tumorigenic Growth; Quantitative Proteomics; Target Identification And Validation; Ubiquitin-Proteasome System (Ups); Usp17; Wnt/-Catenin (Ctnnb1) Signaling Pathway
Characterization of novel effectors that contribute to the fine-tuning of the antiviral cellular response following virus infection
Principal investigators: Servant, Marc
Keywords: Antiviral Innate Immune Response; Cell Signalling; E3 Ubiquitin Ligases; Eif4e-Sensitibe Mrna; Mtor; Polyribosome Profiling; Protein Kinases; Tbk1; Traf3; Translation
Canada Research Chair Tier 2
Principal investigators: Servant, Marc
Keywords: Crc
Deciphering the role of TRK-fused gene (TFG) in antiviral innate immunity
Principal investigators: Marineau, Alexandre
Keywords: Antiviral Assays; Antiviral Response; Antiviral Therapies; Cell Signaling; Innate Immunity; Molecular Biology Techniques; Transcription Factor; Trk-Fused Gene; Type I Interferons Production; Viral Infection
Studying the involvement of the E3 ubiquitin ligase TRAF6 in vascular remodeling events
Principal investigators: Servant, Marc
Keywords: Angiotensin Ii; Atherosclerosis; Conditional Ko Mice; G Protein-Coupled Receptors; Inducible Tet System In Vivo; Polyubiquitination; Protein Kinases; Traf6; Ubiquitin E3 Ligases; Vascular Smooth Muscle Cells
CANADA RESEARCH CHAIRHOLDER – TIER 2 / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA – NIVEAU 2
Principal investigators: Servant, Marc
Keywords: Tier 2 Crc
Understanding the activation and the roles of the IKK complex-NF-kappaB signaling cascade in the inflammatory and hypertrophic actions of Angiotensin II in vitro and in vivo
Principal investigators: Servant, Marc
Keywords: Angiotensin Ii; Atherosclerosis; Chromatin; Hypertension; Kinases; Signal Transduction
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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