This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.
Cell reports · 2017
Latest funding
- $299,640
Novel generative active learning algorithms for exploring the space of antimicrobial peptides to respond to antibiotics resistance
NSERC · 2022 · Co-investigator
- $250,000
Nanoparticle-mediated laser optoporation of CRISPR gene editing enzymes
SSHRC · 2020 · Co-investigator
- $4,664,129
Architecture and chemical modulation of genetic networks
CIHR · 2018 · Nominated PI
1 publications.
Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.
Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, Yi S
Novel generative active learning algorithms for exploring the space of antimicrobial peptides to respond to antibiotics resistance
Principal investigators: Bengio, Yoshua
Nanoparticle-mediated laser optoporation of CRISPR gene editing enzymes
Principal investigators: Meunier, Michel
Architecture and chemical modulation of genetic networks
Principal investigators: Tyers, Michael D
Keywords: Biological Network; Cell Growth And Division; Chemogenomic Profile; Crispr/Cas9; Drug Mechanism Of Action; Genetic Interaction; Proteomics; Synthetic Biology; Synthetic Natural Product; Systems Biology
Genetic and chemical ablation of senescent cells that result from age-dependent telomere erosion
Principal investigators: Harrington, Lea A
Keywords: Age-Associated Diseases; Aging; Cellular Senescence; Chemical Inhibitor; Crispr/Cas9 Genetic Screen; Healthspan; Senolysis; Senotherapeutics; Telomerase Reverse Transcriptase; Telomere Dysfunction
A synthetic biology platform to generate and screen natural product-like chemical space for novel antibiotic activities
Principal investigators: Tyers, Michael D
Keywords: Antibiotic; Bacterial Pathogen; Biosynthetic Enzyme; Cell Microfactory; Cell-Based Assay; Gene Assembly; High Throughput Screen; Natural Product; Synthetic Biology; Yeast Artificial Chromosome
Canada Research Chair - Tier 1 - CIHR Funded
Principal investigators: Tyers, Michael D
Keywords: Crc
Systems biology of cell size homeostasis
Principal investigators: Tyers, Michael D
Keywords: Biochemistry; Biological Network; Cell Division; Cell Growth; Cell Size Homeostasis; Crispr/Cas9; Mass Spectrometry; Mathematical Modeling; Phosphoproteomics; Systematic Genetics
Interrogation of drug and toxin mechanism of action by a matrix of chemogenomic profiles in human cells
Principal investigators: Tyers, Michael D
Keywords: Chemical Biology; Chemical-Genetic Interaction; Crispr/Cas9 Gene Editing; Drug; Drug Discovery; Drug Repurposing; Environmental Toxin; Exposure Hazards; Genetic Network; Mechanism Of Action
Analysis of intrinsically disordered protein structure and function by 3D proteomics
Principal investigators: Coulombe-Huntington, Jasmin
Keywords: Cancer; Cross-Linking; Intrinsic Disorder; Mass Spectrometry; Proteomics; Sic1; Signaling
Modulation of the Cdc34 ubiquitin conjugating enzyme in cancer
Principal investigators: Tyers, Michael D
Keywords: Cell Division; Drug Development; E2 Conjugating Enzyme; E3 Ubiquitin Ligase; Human Cell Line; Mouse Genetic Model; Protein Degradation; Protein Interaction; Small Molecule; Ubiquitin Proteasome System
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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