Nancy Dumais, Université de Sherbrooke

Research

Ccr7 Cell Migration Hiv-1 Monocytes Neuroaids Prostaglandins Cell-Based Drug Delivery Chemokines

Latest papers

Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study.
Asian Pacific journal of allergy and immunology · 2019 · senior author
RAGE and CCR7 mediate the transmigration of Zika-infected monocytes through the blood-brain barrier.
Immunobiology · 2019 · senior author
TLR4 induces CCR7-dependent monocytes transmigration through the blood-brain barrier.
Journal of neuroimmunology · 2016 · senior author

All 13 publications

Latest funding

Modernism and Mysticism: T.S. Eliot, Virginia Woolf, W.B. Yeats, and Rabindranath Tagore
SSHRC · 2023 · Co-investigator
$92,031
Former aux controverses socioscientifiques dans les cours de sciences: Rôle du débat et de l'argumentation
SSHRC · 2023 · Co-investigator
$87,113
Dessine Ta Science
NSERC · 2020 · Principal investigator
$20,000

All 12 grants and awards

13 publications.

01

Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study.

Ksouri L, Mouloud Y, Dumais N

Asian Pacific journal of allergy and immunology2019Senior author

DOI: 10.12932/ap-290318-0290 PMID: 30525746

02

RAGE and CCR7 mediate the transmigration of Zika-infected monocytes through the blood-brain barrier.

de Carvalho GC, Borget MY, Bernier S, Garneau D, da Silva Duarte AJ, Dumais N

Immunobiology2019Senior author

DOI: 10.1016/j.imbio.2019.08.007 PMID: 31493920

03

TLR4 induces CCR7-dependent monocytes transmigration through the blood-brain barrier.

Paradis A, Bernier S, Dumais N

Journal of neuroimmunology2016Senior author

DOI: 10.1016/j.jneuroim.2016.03.019 PMID: 27235343

04

Optimization of an in vitro human blood-brain barrier model: Application to blood monocyte transmigration assays.

Paradis A, Leblanc D, Dumais N

MethodsX2016Senior author

DOI: 10.1016/j.mex.2015.11.009 PMID: 26865992

05

CCR7 Receptor Expression in Mono-MAC-1 Cells: Modulation by Liver X Receptor α Activation and Prostaglandin E 2.

Tanné B, Bernier S, Dumais N

International journal of inflammation2015Senior author

DOI: 10.1155/2015/201571 PMID: 26770865

06

15-Deoxy-Δ(12,14)-prostaglandin J2 inhibits IL-13 production in T cells via an NF-κB-dependent mechanism.

Doyle MC, Tremblay S, Dumais N

Biochemical and biophysical research communications2013Senior author

DOI: 10.1016/j.bbrc.2013.01.036 PMID: 23333326

07

Prostaglandin E 2 Does Not Modulate CCR7 Expression and Functionality after Differentiation of Blood Monocytes into Macrophages.

Allaire MA, Tanné B, Côté SC, Dumais N

International journal of inflammation2013Senior author

DOI: 10.1155/2013/918016 PMID: 24298392

08

Involvement of the MAPK and RhoA/ROCK pathways in PGE2-mediated CCR7-dependent monocyte migration.

Allaire MA, Dumais N

Immunology letters2012Senior author

DOI: 10.1016/j.imlet.2012.05.002 PMID: 22659045

09

CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes.

Wilhelm E, Doyle MC, Nzaramba I, Magdzinski A, Dumais N, Bell B

Retrovirology2012

DOI: 10.1186/1742-4690-9-62 PMID: 22834489

10

High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir.

Pasvanis S, Tremblay S, Dumais N

Biochemical and biophysical research communications2012Senior author

DOI: 10.1016/j.bbrc.2012.01.046 PMID: 22293191

Modernism and Mysticism: T.S. Eliot, Virginia Woolf, W.B. Yeats, and Rabindranath Tagore

Co-investigatorSSHRC2023Insight Grants

Principal investigators: McIntire, Gabrielle S.

Keywords: literary modernism; mysticism; early twentieth-centiry literature; religion and literature; poetry; poetics; theories of the sacred; secularity; agnosticism; atheism; T.S. Eliot; Virginia Woolf; W.B. Yeats; Rabindranath Tagore

$92,031

Former aux controverses socioscientifiques dans les cours de sciences: Rôle du débat et de l'argumentation

Co-investigatorSSHRC2023Insight Grants

Principal investigators: Hasni, Abdelkrim

Keywords: controverses socioscientifiques; argumentation scientifique; formation scientifique; pensée critique; virus du papillome humain (VPH); sars-cov-2 (COVID-19)

$87,113

Dessine Ta Science

Principal investigatorNSERC2020Science Communication Skills Grant

Principal investigators: Dumais, Nancy

$20,000

Acquisition of an Automated High-Throughput Cell Imaging System

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Maréchal, Alexandre

$150,000

Acquisition of a liquid scintillation counter

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Lafontaine, Daniel

$52,434

Novel insights into the regulation of CCR7 receptor expression in immune cells

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Dumais, Nancy

$150,000

L'enseignement par projets en sciences et technologies au primaire et au secondaire: significations, finalités et modalités de mise en oeuvre

Co-investigatorSSHRC2013

Principal investigators: Hasni, Abdelkrim

Keywords: éducation scientifique et technologique (didactique des sciences et technologies); finalités éducatives et curriculum; approches pédagogiques (par projets; interdisciplinaires); démarches d'enseignement; formation des enseignants

$158,900

CCR7-dependent migration of monocytes: Implication in HIV-1 dissemination to reservoirs.

Nominated PICIHR2012Operating Grant - PA: HIV/AIDS Bridge Funding - Biomedical/Clinical Stream

Principal investigators: Dumais, Nancy

Keywords: Ccr7; Cell Migration; Cell-Based Drug Delivery; Chemokines; Hiv-1; Monocytes; Nanoart; Neuroaids; Prostaglandins

$100,000

CCR7-dependent migration of monocytes: Implication in HIV-1 dissemination and treatment.

Nominated PICIHR2012Operating Grant - PA: HIV/AIDS Bridge Funding - Biomedical/Clinical Stream

Principal investigators: Dumais, Nancy

Keywords: Ccr7; Cell Migration; Cell Signaling; Cell-Based Drug Delivery System; Co-Culture Model; Hiv-1; Monocytes; Nanoformulated Antiretroviral Drugs; Neuroaids; Prostaglandins

$100,000

Importance of PGE2 in CCR7-dependent migration of monocytes/macrophages to lymph nodes and implication in HIV-1 dissemination.

Nominated PICIHR2008Operating Grant

Principal investigators: Dumais, Nancy

Keywords: Cell Migration; Chemokines And Cytokines; Hiv-1; Mucosal Transmission; Prostaglandins

$267,126

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Brendan Bell

Faculty

1 shared papers, latest 2012

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: Ccr7 Dear Professor Dumais, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study." (2019), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Dessine Ta Science" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Nancy Dumais

Research

Latest papers

Latest funding

Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study.

RAGE and CCR7 mediate the transmigration of Zika-infected monocytes through the blood-brain barrier.

TLR4 induces CCR7-dependent monocytes transmigration through the blood-brain barrier.

Optimization of an in vitro human blood-brain barrier model: Application to blood monocyte transmigration assays.

CCR7 Receptor Expression in Mono-MAC-1 Cells: Modulation by Liver X Receptor &#x3b1; Activation and Prostaglandin E 2.

15-Deoxy-&#x394;(12,14)-prostaglandin J2 inhibits IL-13 production in T cells via an NF-&#x3ba;B-dependent mechanism.

Prostaglandin E 2 Does Not Modulate CCR7 Expression and Functionality after Differentiation of Blood Monocytes into Macrophages.

Involvement of the MAPK and RhoA/ROCK pathways in PGE2-mediated CCR7-dependent monocyte migration.

CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes.

High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-&#x394;(12,14)-prostaglandin J(2) on the resistance to saquinavir.

Modernism and Mysticism: T.S. Eliot, Virginia Woolf, W.B. Yeats, and Rabindranath Tagore

Former aux controverses socioscientifiques dans les cours de sciences: Rôle du débat et de l'argumentation

Dessine Ta Science

Acquisition of an Automated High-Throughput Cell Imaging System

Acquisition of a liquid scintillation counter

Novel insights into the regulation of CCR7 receptor expression in immune cells

L'enseignement par projets en sciences et technologies au primaire et au secondaire: significations, finalités et modalités de mise en oeuvre

CCR7-dependent migration of monocytes: Implication in HIV-1 dissemination to reservoirs.

CCR7-dependent migration of monocytes: Implication in HIV-1 dissemination and treatment.

Importance of PGE2 in CCR7-dependent migration of monocytes/macrophages to lymph nodes and implication in HIV-1 dissemination.

Frequent collaborators

Brendan Bell

CCR7 Receptor Expression in Mono-MAC-1 Cells: Modulation by Liver X Receptor α Activation and Prostaglandin E 2.

15-Deoxy-Δ(12,14)-prostaglandin J2 inhibits IL-13 production in T cells via an NF-κB-dependent mechanism.

High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir.