Changting Xiao, University of Saskatchewan

Research

Animal Dyslipidemia Hormones In Vivo Integrative Physiology Intestine Lipids And Lipoproteins Metabolism And Metabolic Disorders

Latest papers

Secretion of Extracellular Vesicles Into the Mesenteric Lymph During Fasting and Lipid Absorption.
Journal of extracellular biology · 2026 · senior author
The Role of Vasoactive Intestinal Peptide in Glucagon-like Peptide-2-Mediated Intestinal Lipid Handling.
International journal of molecular sciences · 2026 · senior author
Glucagon-like Peptide-2 Acts Partially Through Central GLP-2R and MC4R in Mobilizing Stored Lipids from the Intestine.
Nutrients · 2025 · senior author

All 13 publications

Latest funding

Regulation of intestinal lipid storage and release in metabolic health and disease
CIHR · 2023 · Nominated PI
$772,650
Regulation of Cytoplasmic Lipid Droplet Mobilization in Intestinal Enterocyte
NSERC · 2021 · Principal investigator
$12,500
Regulation of Cytoplasmic Lipid Droplet Mobilization in Intestinal Enterocyte
NSERC · 2021 · Principal investigator
$148,000

All 3 grants and awards

13 publications.

01

Secretion of Extracellular Vesicles Into the Mesenteric Lymph During Fasting and Lipid Absorption.

Hang T, Wang R, Mukherjee K, Sandhu U, Xiao F, Burger D, Xiao C

Journal of extracellular biology2026Senior author

DOI: 10.1002/jex2.70170 PMID: 42494780

02

The Role of Vasoactive Intestinal Peptide in Glucagon-like Peptide-2-Mediated Intestinal Lipid Handling.

Mukherjee K, Wang R, Tabatabaeian F, Xiao C

International journal of molecular sciences2026Senior author

DOI: 10.3390/ijms27125457 PMID: 42353173

03

Glucagon-like Peptide-2 Acts Partially Through Central GLP-2R and MC4R in Mobilizing Stored Lipids from the Intestine.

Mukherjee K, Khan MSA, Howland JG, Xiao C

Nutrients2025Senior author

DOI: 10.3390/nu17091416 PMID: 40362725

04

Glucose-dependent insulinotropic polypeptide stimulates post-absorptive lipid secretion in the intestine.

Wang R, Khan MSA, Mukherjee K, Ghanem M, Xiao C

Frontiers in physiology2025Senior author

DOI: 10.3389/fphys.2025.1549392 PMID: 40255636

05

GLP-2 regulation of intestinal lipid handling.

Mukherjee K, Xiao C

Frontiers in physiology2024Senior author

DOI: 10.3389/fphys.2024.1358625 PMID: 38426205

06

Release of Lipids Stored in the Intestine by Glucagon-Like Peptide-2 Involves a Gut-Brain Neural Pathway.

Mukherjee K, Wang R, Xiao C

Arteriosclerosis, thrombosis, and vascular biology2024Senior author

DOI: 10.1161/atvbaha.123.320032 PMID: 37970717

07

Glucagon-like Peptide-2 Acutely Enhances Chylomicron Secretion in Humans Without Mobilizing Cytoplasmic Lipid Droplets.

Syed-Abdul MM, Stahel P, Zembroski A, Tian L, Xiao C, Nahmias A, Bookman I, Buhman KK, Lewis GF

The Journal of clinical endocrinology and metabolism2023

DOI: 10.1210/clinem/dgac690 PMID: 36458872

08

Recent advances in cytoplasmic lipid droplet metabolism in intestinal enterocyte.

Ghanem M, Lewis GF, Xiao C

Biochimica et biophysica acta. Molecular and cell biology of lipids2022Senior author

DOI: 10.1016/j.bbalip.2022.159197 PMID: 35820577

09

Glucagon-like peptide-2 mobilization of intestinal lipid does not require canonical enterocyte chylomicron synthetic machinery.

Syed-Abdul MM, Stahel P, Tian L, Xiao C, Nahmias A, Lewis GF

Biochimica et biophysica acta. Molecular and cell biology of lipids2022

DOI: 10.1016/j.bbalip.2022.159194 PMID: 35680083

10

Lymphatics - not just a chylomicron conduit.

Syed-Abdul MM, Tian L, Xiao C, Lewis GF

Current opinion in lipidology2022

DOI: 10.1097/mol.0000000000000821 PMID: 35258031

Regulation of intestinal lipid storage and release in metabolic health and disease

Nominated PICIHR2023Project Grant

Principal investigators: Xiao, Changting

Keywords: Animal; Dyslipidemia; Hormones; In Vivo; Integrative Physiology; Intestine; Lipids And Lipoproteins; Metabolism And Metabolic Disorders

$772,650

Regulation of Cytoplasmic Lipid Droplet Mobilization in Intestinal Enterocyte

Principal investigatorNSERC2021Discovery Launch Supplement

Principal investigators: Xiao, Changting

$12,500

Regulation of Cytoplasmic Lipid Droplet Mobilization in Intestinal Enterocyte

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Xiao, Changting

$148,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Dylan Burger

Cellular and Molecular Medicine

1 shared papers, latest 2026

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Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Animal Dear Professor Xiao, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Secretion of Extracellular Vesicles Into the Mesenteric Lymph During Fasting and Lipid Absorption." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Regulation of intestinal lipid storage and release in metabolic health and disease" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]