Clarence Geyer

Ultrasound molecular imaging of intestinal stenosis: Developing a contrast agent to distinguish between inflammatory and fibrotic strictures in patients with inflammatory bowel disease

Principal investigators: Machtaler, Steven B

Keywords: Aptamers; Bowel Strictures; Inflammation; Inflammatory Bowel Disease; Microbubbles; Ultrasound Molecular Imaging

A theranostic probe targeting the tumor-associated xenoantigen N-Glycoylneuramic acid GM3 ganglioside (Neu5Gc GM3)

Principal investigators: Geyer, Clarence R; Price, Eric W

Keywords: 177-Lutetium; 90-Yttrium; H14f7 Antibody; Neu5gc Gm3; Radio-Immunotherapy; Solid Tumors; Spect-Ct; Theranostic; Xeno-Antigen

Tumor targeted, radiolabeled, mimetic nanovesicle theranostics for imaging and treating head and neck cancer

Principal investigators: Price, Eric W; Geyer, Clarence R

Keywords: Bioconjugation Chemistry; Head And Neck Cancer; Mimetic Nanovesicle; Nanoparticles; Positron Emission Tomography; Radioimmunotherapy; Radionuclide Therapy; Targeted Radionuclide Therapy; Theranostics; Zirconium-89

Simultaneous targeting of multiple domains of HER2 and EGFR using domain-specific alpha particle labeled radioimmunoconjugates

Principal investigators: Fonge, Humphrey A

Keywords: Alpha Particle Radiotherapy; Antibody Drug Conjugates; Breast Cancers; Egfr; Her2; Micropet Imaging; Mouse Models; Nuclear Medicine; Personalized Medicine; Radioimmunotherapy

Design of synthetic recombinant antibody devices for applications in molecular targeted imaging

Principal investigators: Geyer, Clarence

Alpha particle-labeled antibody-drug radioconjugates for radiotherapy of metastatic colorectal cancer (mCRC)

Principal investigators: Fonge, Humphrey A

Keywords: Actinium-225; Alpha Particle Radiotherapy; Epidermal Growth Factor Receptor; Metastic Colorectal Cancer; Patient Derived Xenografts; Precision Medicine; Radiation Dosimetry; Radioimmunotherapy; Radiopharmaceuticals; Spect/Pet Imaging

Systematic profiling of circular RNAs essential for the survival of cancer cells

Principal investigators: Vizeacoumar, Franco J; Geyer, Clarence R

Keywords: Circularrnas; Non-Coding Rnas

Antibodies Targeting the ErbB2/ErbB3/IGF-1R Complex as Therapeutics for ErbB2 Positive Breast Cancer

Principal investigators: Liu, Jianghai

Keywords: Antibody Therapy For Breast Cancer; Erbb Receptors; Igf-1 Receptor; Phage Display

The Role of Insulin-like Growth Factor-1 (IGF-1) Signaling on Chronic Phase and Blast Crisis Phase of Chronic Myeloid Leukemia

Principal investigators: Abrishami, Mahsa

Keywords: Chronic Myeloid Leukemia Stem Cells; Cytokines; Innate Imatinib Resistance Mechanisms; Insulin-Like Growth Factor And Drug Resistance In Leukemia

The Role of Natural Antisense Transcripts in Silencing Transforming Growth Factor Beta Regulated Genes in Acute Myeloid Leukemia

Principal investigators: Geyer, Clarence R

Keywords: Acute Leukemia; Cyclin-Dependent Kinase Inhibitors; Dna Methylation; Epigenetics; Histone H3k9 Methylation; Histone Modifications; Natural Antisense Transcripts; Transforming Growth Factor Beta