Faculty profile

Darren Freed

ResearcherMechanical EngineeringUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Darren Freed

Researcher

Mechanical Engineering

Health Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Principal investigator on 3 research grants (2 CIHR, 1 NSERC), most recently in 2019.
Supervised 2 trainees who won CIHR awards, most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Heart Transplant Organ Perfusion Organ Preservation Heart Transplantation Organ Perfusion And Preservation

Latest papers

Perfusion-based delivery of an ice recrystallization inhibitor in rat liver tissue.
Cryobiology · 2026
From the Bench to the Bedside and Back: Contemporary Applications of Basic Science to Innovations in Heart Transplantation.
The Canadian journal of cardiology · 2026
Rejection and graft vasculopathy secondary to effects of Crohn's disease in a heart-transplanted child.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025

All 11 publications

Latest funding

Comparing the Mechanical Impacts of Tissue Preservation Protocols on Tissues Utilized for Surgical Reconstruction of Congenital Heart Defects
CIHR · 2026 · Supervisor
$9,000
Ex-vivo Heart Perfusion for Donor Heart Reconstitution via Metabolic Optimization
CIHR · 2025 · Supervisor
$120,000
Optimizing resuscitation of the donation after circulatory death (DCD) heart by mitochondrial redox regulation and opioid receptor activation: a protocol for clinical application
CIHR · 2020 · Co-investigator
$715,276

All 7 grants and awards

11 publications.

Perfusion-based delivery of an ice recrystallization inhibitor in rat liver tissue.

Himmat S, Ma I, William N, Foxcroft M, Hefler J, Hatami S, Wang X, Taggart M, Thiessen A, Freed D, Nagendran J, Acker J

Cryobiology2026

DOI: 10.1016/j.cryobiol.2026.105688 PMID: 42607523

From the Bench to the Bedside and Back: Contemporary Applications of Basic Science to Innovations in Heart Transplantation.

Truby LK, Sharma G, Watson WD, Halloran PF, Hussain T, Madill-Thomsen KS, Esmailian G, Fung N, Peyster E, Moayedi Y, Rao V, Freed D, Bowles DE, Peltz M, Billia F

The Canadian journal of cardiology2026

DOI: 10.1016/j.cjca.2025.11.008 PMID: 41232766

Rejection and graft vasculopathy secondary to effects of Crohn's disease in a heart-transplanted child.

Oliver S, Conway J, Freed D, Halpin A, Huynh H, Khoury M, Kluthe C, Dijke E, West L, Urschel S

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2025

DOI: 10.1016/j.ajt.2025.04.020 PMID: 40306436

Moderate-Flow Perfusion is Superior to Low-Flow Perfusion in Ex Situ Lung Perfusion.

Forgie K, Fialka N, Watkins A, Du K, Himmat S, Hatami S, Khan M, Wang X, Edgar R, Buswell-Zuk KM, Freed D, Nagendran J

Transplantation proceedings2024

DOI: 10.1016/j.transproceed.2024.08.032 PMID: 39242316

Evaluating the Prevalence and Factors Associated With an Optimal Neurodevelopmental Outcome in 4- to 6-Year-Old Children With Fontan Circulation.

Khoury M, Hajihosseini M, Robertson CMT, Bond G, Freed D, Dinu I, Makarchuk S, Joffe A, Atallah J, Western Canadian Complex Pediatric Therapies Follow-up Group

The Canadian journal of cardiology2023

DOI: 10.1016/j.cjca.2022.10.022 PMID: 36544295

Impact of sex on long-term outcomes following mitral valve repair.

El-Andari R, Bozso SJ, Kang JJH, Boe D, Fialka NM, Hong Y, Moon MC, Freed D, Nagendran J, Nagendran J

American heart journal plus : cardiology research and practice2021

DOI: 10.1016/j.ahjo.2021.100004 PMID: 38560361

A Decrease in Hypoxic Pulmonary Vasoconstriction Correlates With Increased Inflammation During Extended Normothermic Ex Vivo Lung Perfusion.

Himmat S, Alzamil A, Aboelnazar N, Hatami S, White C, Dromparis P, Mengel M, Freed D, Nagendran J

Artificial organs2018

DOI: 10.1111/aor.13017 PMID: 29266272

Impact of Reperfusion Calcium and pH on the Resuscitation of Hearts Donated After Circulatory Death.

White C, Avery E, Müller A, Hatami S, Li Y, Le H, Thliveris J, Arora R, Lee T, Dixon I, Tian G, Nagendran J, Hryshko L, Freed D

The Annals of thoracic surgery2017Senior author

DOI: 10.1016/j.athoracsur.2016.05.084 PMID: 27526656

Canadian Guidelines for Controlled Pediatric Donation After Circulatory Determination of Death—Summary Report*

Weiss MJ, Hornby L, Rochwerg B, van Manen M, Dhanani S, Sivarajan VB, Appleby A, Bennett M, Buchman D, Farrell C

Pediatric Critical Care Medicine201763 citations

DOI: 10.1097/pcc.0000000000001320

Assessment of donor heart viability during ex vivo heart perfusion.

White CW, Ambrose E, Müller A, Li Y, Le H, Hiebert B, Arora R, Lee TW, Dixon I, Tian G, Nagendran J, Hryshko L, Freed D

Canadian journal of physiology and pharmacology2015Senior author

DOI: 10.1139/cjpp-2014-0474 PMID: 26317524

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Darren Freed

Research

Latest papers

Latest funding

Perfusion-based delivery of an ice recrystallization inhibitor in rat liver tissue.

From the Bench to the Bedside and Back: Contemporary Applications of Basic Science to Innovations in Heart Transplantation.

Rejection and graft vasculopathy secondary to effects of Crohn's disease in a heart-transplanted child.

Moderate-Flow Perfusion is Superior to Low-Flow Perfusion in Ex Situ Lung Perfusion.

Evaluating the Prevalence and Factors Associated With an Optimal Neurodevelopmental Outcome in 4- to 6-Year-Old Children With Fontan Circulation.

Impact of sex on long-term outcomes following mitral valve repair.

A Decrease in Hypoxic Pulmonary Vasoconstriction Correlates With Increased Inflammation During Extended Normothermic Ex Vivo Lung Perfusion.

Impact of Reperfusion Calcium and pH on the Resuscitation of Hearts Donated After Circulatory Death.

Canadian Guidelines for Controlled Pediatric Donation After Circulatory Determination of Death—Summary Report*

Assessment of donor heart viability during ex vivo heart perfusion.

Comparing the Mechanical Impacts of Tissue Preservation Protocols on Tissues Utilized for Surgical Reconstruction of Congenital Heart Defects

Ex-vivo Heart Perfusion for Donor Heart Reconstitution via Metabolic Optimization

Optimizing resuscitation of the donation after circulatory death (DCD) heart by mitochondrial redox regulation and opioid receptor activation: a protocol for clinical application

Optimization of an ex vivo heart perfusion device for pre-transplant preservation and evaluation of donor hearts

Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts

Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts

The Canadian National Transplant Research Program: Increasing Donation and Improving Transplantation Outcomes

Frequent collaborators

Ian Dixon

Rakesh Arora

Jason Acker

Bram Rochwerg

Sonny Dhanani

Sonny Dhanani

Yasbanoo Moayedi

Anne Halpin

Anne Dipchand

Sonny Dhanani

Kevin Coughlin

Cynthia Cupido

Lori West

Michael Van Manen

Filio Billia

Sonny Dhanani

Sonny Dhanani

Daniel Buchman

Bram Rochwerg

Kevin Coughlin