This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Ovarian carcinosarcoma (malignant mixed Müllerian tumor, MMMT) in a premenopausal woman: a diagnostic challenge-a case report.
Journal of medical case reports · 2026
Dual intestinal-hepatic modulation by phenolic acids improves metabolic-dysfunction associated steatohepatitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026 · senior author
Phenolic acids from Anisopus mannii modulates phosphofructokinase 1 to improve glycemic control in patients with type 2 diabetes: A double-blind, randomized, clinical trial.
Pharmacological research · 2025
Latest funding
- $1,051,876
Dissecting the molecular mechanisms regulating the low-density lipoprotein receptor, the role of prosaposin
CIHR · 2026 · Nominated PI
- $944,775
Molecular mechanism and pathophysiological consequences of disrupted vitamin A homeostasis during iron deficiency
CIHR · 2025 · Co-investigator
- $1,067,175
Dissecting the cell type-specific role of MT1-MMP/MMP14 in the development of liver fibrosis
CIHR · 2025 · Nominated PI
7 publications.
Ovarian carcinosarcoma (malignant mixed Müllerian tumor, MMMT) in a premenopausal woman: a diagnostic challenge-a case report.
Ailun G, Li Y, Zhang D, Fu Y, Su X, Yu C
Dual intestinal-hepatic modulation by phenolic acids improves metabolic-dysfunction associated steatohepatitis.
Amadi PU, Osuoha JO, Amadi JA, Efiong EE, Odika PC, Ekweogu CE, Ejiofor C, Gill GS, Jarad SJ, Amadi CW, Gu H, de Courten B, Agomuo EN, Zhang D
Phenolic acids from Anisopus mannii modulates phosphofructokinase 1 to improve glycemic control in patients with type 2 diabetes: A double-blind, randomized, clinical trial.
Amadi PU, Osuoha JO, Ekweogu CN, Jarad SJ, Efiong EE, Odika PC, Ejiofor C, Aloy-Amadi O, Gill GS, Adumekwe CW, Gaowa A, Zhang D, de Courten B, Agomuo EN
The role of CoQ10 in embryonic development.
He X, Chen H, Liao M, Zhao X, Zhang D, Jiang M, Jiang Z
Interleukin-5 promotes ATP-binding cassette transporter A1 expression through miR-211/JAK2/STAT3 pathways in THP-1-dervied macrophages.
Chen K, Zhao Z, Wang G, Zou J, Yu X, Zhang D, Zeng G, Tang C
HDL impairs osteoclastogenesis and induces osteoclast apoptosis via upregulation of ABCG1 expression.
Huang X, Lv Y, He P, Wang Z, Xiong F, He L, Zheng X, Zhang D, Cao Q, Tang C
MMP-2 inhibits PCSK9-induced degradation of the LDL receptor in Hepa1-c1c7 cells.
Wang X, Berry E, Hernandez-Anzaldo S, Sun D, Adijiang A, Li L, Zhang D, Fernandez-Patron C
Dissecting the molecular mechanisms regulating the low-density lipoprotein receptor, the role of prosaposin
Principal investigators: Zhang, Dawei
Keywords: Adeno-Associated Virus; Atherosclerosis; Cell Tulture; Gene Knockdown; Lipoprotein Metabolism; Low-Density Lipoprotein Receptor; Prosaposin; Protein Recycling And Degradation
Molecular mechanism and pathophysiological consequences of disrupted vitamin A homeostasis during iron deficiency
Principal investigators: Clugston, Robin D; Bourque, Stephane
Keywords: Iron Deficiency; Liver; Vitamin A Deficiency
Dissecting the cell type-specific role of MT1-MMP/MMP14 in the development of liver fibrosis
Principal investigators: Zhang, Dawei
Keywords: Extracellular Matrix; Fatty Liver; Hepatic Stellate Cells; Immunohistochemistry; Knockout Mice; Lipid Metabolism; Liver Fibrosis; Liver Steatosis; Matrix Metalloproteinase; Triglycerides
Molecular mechanism and regulation of cellular cholesterol homeostasis-ABC transporters and PCSK9
Principal investigators: Zhang, Dawei
Keywords: cellular cholesterol homeostasis; cholesterol uptake and efflux; atp-binding cassette transporter; proprotein convertase subtilisin/kexin type 9; low density lipoprotein receptor; cell culture; palmitoylation; immunoprecipitation and western blot; real-time quantitative reverse transcription pcr; endocytosis
Preclinical trial of a CAROtenoid-PHENolic acid premix (CaroPhen) for the treatment of advanced liver fibrosis
Principal investigators: Amadi, Peter U
Keywords: Alternative Medicine; Liver Fibrosis; Masld
Investigating the role of Monooxygenase X in liver steatosis and fibrosis.
Principal investigators: Gill, Govind S
Keywords: De Novo Lipogenesis; Fatty Acid Oxidation; Fatty Liver; Hepatic Stellate Cells; Hepatocytes; Lipid Droplets; Lipid Metabolism; Liver Fibrosis; Nutrition; Very Low Density Lipoproteins
Dissecting the role and underlying mechanism of Surf4 in regulating lipid metabolism
Principal investigators: Zhang, Dawei
Keywords: Adeno-Associated Virus; Atherosclerosis; Cargo Receptor; Dyslipidemia; Gene Knockdown; Lipid Metabolism; Lipoprotein Secretion; Plasma Ldl Cholesterol; Triglyceride; Very Low Density Lipoprotein
Understanding of the physiological role of membrane-type I matrix metalloproteinase in lipid metabolism
Principal investigators: Zhang, Dawei
Keywords: Apoe Knockout Mice; Atherosclerosis; Cholesterol Homeostasis; Cultured Cells; Ldl Receptor Knockout Mice; Lipid Metabolism; Low Density Lipoprotein; Low Density Lipoprotein Receptor; Matrix Metalloproteinase 14; Receptor Shedding
Cholesterol homeostasis and pancreatic beta cell function
Principal investigators: Zhang, Dawei
Molecular mechanisms of ABC transporters-mediated sterol transport
Principal investigators: Zhang, Dawei
Keywords: Atp Binding Cassette Transporters; Cell Culture; Cholesterol Efflux; High Density Lipoprotein; Protein Protein Interaction; Protein Purification
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.