This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses and email address may be missing. Find their university profile.
Latest papers
Bioinspired computational design of lankacidin derivatives for improvement in antitumor activity.
Future medicinal chemistry · 2022
Real-Time Monitoring of the Effect of Tumour-Treating Fields on Cell Division Using Live-Cell Imaging.
Cells · 2022
Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives.
Bioorganic & medicinal chemistry · 2022
Latest funding
- $730,576
FOXM1 protein-targeted degradation and its potential role in the treatment of ovarian cancer: a medicinal chemistry approach
CIHR · 2022 · Co-investigator
- $918,000
Cancer Therapy exploiting Conditional Synthetic Lethality based on Genotoxic Stress levels
CIHR · 2018 · Co-investigator
- $198,000
Structure and function of the RZZ complex, an essential mitotic checkpoint complex.
NSERC · 2016 · Principal investigator
8 publications.
Bioinspired computational design of lankacidin derivatives for improvement in antitumor activity.
Ayoub AT, Nishiura N, Teshima A, Elrefaiy MA, Muslimin R, Do KM, Kodama T, Lewis CW, Chan G, Morita H, Arakawa K
Real-Time Monitoring of the Effect of Tumour-Treating Fields on Cell Division Using Live-Cell Imaging.
Le HT, Staelens M, Lazzari D, Chan G, Tuszyński JA
Chemoenzymatic synthesis, computational investigation, and antitumor activity of monocyclic lankacidin derivatives.
Muslimin R, Nishiura N, Teshima A, Do KM, Kodama T, Morita H, Lewis CW, Chan G, Ayoub AT, Arakawa K
Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxel.
Lewis CW, Jin Z, Macdonald D, Wei W, Qian XJ, Choi WS, He R, Sun X, Chan G
Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism.
Ayoub AT, Abou El-Magd RM, Xiao J, Lewis CW, Tilli TM, Arakawa K, Nindita Y, Chan G, Sun L, Glover M, Klobukowski M, Tuszynski J
Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration.
Ou Y, Chan G, Zuo J, Rattner JB, van der Hoorn FA
Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint.
Famulski JK, Vos L, Sun X, Chan G
Epigenetic regulation of centromere formation and kinetochore function.
Heit R, Underhill DA, Chan G, Hendzel MJ
FOXM1 protein-targeted degradation and its potential role in the treatment of ovarian cancer: a medicinal chemistry approach
Principal investigators: Velazquez, Carlos A
Keywords: Drug Design; Forkhead Box Proteins; Foxm1; Medicinal Chemistry; Molecular Modeling; Ovarian Cancer; Transcription; Transcription Factors
Cancer Therapy exploiting Conditional Synthetic Lethality based on Genotoxic Stress levels
Principal investigators: Gamper, Armin
Keywords: Breast Cancer; Cell Cycle Checkpoints; Dna Damage Response; Mouse Xenograft Models; Replication Stress; Synthetic Lethality
Structure and function of the RZZ complex, an essential mitotic checkpoint complex.
Principal investigators: Chan, Gordon
Structure and function of Mis12 (Minichromosome Instability) centromere complex in mitosis
Principal investigators: Chan, Gordon
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Jack Tuszynski and Mariusz Klobukowski: 4 shared papers
- Jack Tuszynski and Gordon Chan: 1 shared paper
- Gordon Chan and Mariusz Klobukowski: 1 shared paper
- Oncology
- Chemistry
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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