Faculty profile
Hongquan Zhang
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Research
Latest papers
Incorporating CRISPR Techniques with Electrochemical Sensors: From Signal-Off to Signal-On Assays.
ACS sensors · 2026
A kinetic approach for mapping seed regions of CRISPR ribonucleoprotein and improving specificity.
Nucleic acids research · 2026
Spherical Nucleic Acids-Directed Cryosynthesis of Manganese Nanoagents for Tumor Imaging and Therapy.
Angewandte Chemie (International ed. in English) · 2025
Latest funding
Point-of-care diagnostics of COVID-19 using isothermal amplification and CRISPR technology
CIHR · 2020 · Co-investigator
- $216,000
Construction of deoxyribonucleic acid motors enabling single-molecule detection
NSERC · 2019 · Principal investigator
- $160,000
Binding-Induced DNA Assembly and Novel Applications to Ultrasensitive Detection of Proteins
NSERC · 2013 · Principal investigator
62 publications.
Incorporating CRISPR Techniques with Electrochemical Sensors: From Signal-Off to Signal-On Assays.
Yang C, Hu J, Zhang H, Le XC
A kinetic approach for mapping seed regions of CRISPR ribonucleoprotein and improving specificity.
Feng W, Hu J, Zhang H, Le XC
Spherical Nucleic Acids-Directed Cryosynthesis of Manganese Nanoagents for Tumor Imaging and Therapy.
Xie W, Hao Q, Ye Z, Sha R, Wen B, Wang H, Zhang H, Jia G, Le XC, Jiang G, Peng H
Protein-Induced DNA Dumbbell Amplification (PINDA) and its applications to food hazards detection.
Pang B, Reid MS, Wei J, Peng H, Bu L, Li J, Zhang H, Le XC
RNA-Activated CRISPR/Cas12a Nanorobots Operating in Living Cells.
Yuan A, Sha R, Xie W, Qu G, Zhang H, Wang H, Le XC, Jiang G, Peng H
Integration of a Cas12a-mediated DNAzyme actuator with efficient RNA extraction for ultrasensitive colorimetric detection of viral RNA.
Xiao H, Xu J, Liu Y, Feng W, Pang B, Tao J, Zhang H
Detection of Uracil-Excising DNA Glycosylases in Cancer Cell Samples Using a Three-Dimensional DNAzyme Walker.
Tao J, Zhang H, Weinfeld M, Le XC
A Sensitive Technique Unravels the Kinetics of Activation and Trans-Cleavage of CRISPR-Cas Systems.
Feng W, Peng H, Zhang H, Weinfeld M, Le XC
Development of a DNAzyme Walker for the Detection of APE1 in Living Cancer Cells.
Tao J, Zhang H, Weinfeld M, Le XC
Recent advances in RNA sample preparation techniques for the detection of SARS-CoV-2 in saliva and gargle.
Liu Y, Kumblathan T, Tao J, Xu J, Feng W, Xiao H, Hu J, Huang CV, Wu Y, Zhang H, Li XF, Le XC
Point-of-care diagnostics of COVID-19 using isothermal amplification and CRISPR technology
Principal investigators: Le, Xiaochun C
Keywords: Analytical Techniques; Covid-19; Crispr/Cas; Global Health; Isothermal Amplification Of Nucleic Acids; Molecular Assays; Molecular Biology; Nanotechnology; Point-Of-Care Test; Sars-Cov-2
Construction of deoxyribonucleic acid motors enabling single-molecule detection
Principal investigators: Zhang, Hongquan
Keywords: Binding-induced DNA assembly; Bioanalytical chemistry; Biomarker; Early disease detection; Fluoresence; Molecular motors; Protein detection; Signal amplification; Single-molecule detection; Ultra-sensitive detection
Binding-Induced DNA Assembly and Novel Applications to Ultrasensitive Detection of Proteins
Principal investigators: Zhang, Hongquan
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Hongquan Zhang and Xing-Fang Li: 29 shared papers
- Michael Weinfeld and Hongquan Zhang: 3 shared papers
- Michael Weinfeld and Xing-Fang Li: 2 shared papers
- Department of Laboratory Medicine and Pathology
- Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology
- Oncology
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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