Scot Simpson, University of Alberta

Research

Cardiovascular System Diabetes Health Outcomes Mortality Pharmacotherapy Population Health

Latest papers

Metformin as First-line Therapy: Response to Drs Trinacty and Goldenberg.
Canadian journal of diabetes · 2025 · senior author
Uptake of SGLT2i and Outcomes in Patients with Diabetes and Heart Failure: A Population-Based Cohort and a Specialized Clinic Cohort.
American heart journal · 2024
Effect of a pharmacy comprehensive chronic diseases care plan on use of lipid-lowering drugs among patients with hypertension.
Journal of managed care & specialty pharmacy · 2021

All 8 publications

Latest funding

Novel protective roles for ATP-sensitive potassium channels in the heart
CIHR · 2018 · Co-investigator
$755,440
International Population-Based Evaluation of Drug Therapies Used to Manage Type 2 Diabetes
CIHR · 2012 · Principal investigator
$176,644
Is there a dose-response relationship between glyburide and cardiovascular outcomes?
CIHR · 2011 · Nominated PI
$160,983

All 4 grants and awards

8 publications.

01

Metformin as First-line Therapy: Response to Drs Trinacty and Goldenberg.

Shah BR, Bajaj HS, Butalia S, Dasgupta K, Eurich DT, Jain R, Mansell K, Simpson S

Canadian journal of diabetes2025Senior author

DOI: 10.1016/j.jcjd.2024.12.006 PMID: 40155189

02

Uptake of SGLT2i and Outcomes in Patients with Diabetes and Heart Failure: A Population-Based Cohort and a Specialized Clinic Cohort.

Gagnon LR, Hazra D, Perera K, Wang K, Kashyap N, Sadasivan C, Youngson E, Chu L, Dover DC, Kaul P, Simpson S, Bello A, McAlister FA, Oudit GY

American heart journal2024

DOI: 10.1016/j.ahj.2024.04.007 PMID: 38670300

03

Effect of a pharmacy comprehensive chronic diseases care plan on use of lipid-lowering drugs among patients with hypertension.

Zongo A, Simpson S, Johnson JA, Eurich DT

Journal of managed care & specialty pharmacy2021

DOI: 10.18553/jmcp.2021.27.4.426 PMID: 33769856

04

Pharmacologic Glycemic Management of Type 2 Diabetes in Adults: 2020 Update.

Diabetes Canada Clinical Practice Guidelines Expert Committee, Lipscombe L, Butalia S, Dasgupta K, Eurich DT, MacCallum L, Shah BR, Simpson S, Senior PA

Canadian journal of diabetes2020Senior author

DOI: 10.1016/j.jcjd.2020.08.001 PMID: 32972640

05

Change in Trajectories of Adherence to Lipid-Lowering Drugs Following Non-Fatal Acute Coronary Syndrome or Stroke.

Zongo A, Simpson S, Johnson JA, Eurich DT

Journal of the American Heart Association2019

DOI: 10.1161/jaha.119.013857 PMID: 31771443

06

Optimal threshold of adherence to lipid lowering drugs in predicting acute coronary syndrome, stroke, or mortality: A cohort study.

Zongo A, Simpson S, Johnson JA, Eurich DT

PloS one2019

DOI: 10.1371/journal.pone.0223062 PMID: 31553787

07

Text messaging interventions for individuals with mental health disorders including substance use: A systematic review.

Watson T, Simpson S, Hughes C

Psychiatry research2016

DOI: 10.1016/j.psychres.2016.06.050 PMID: 27423123

08

Diabetes that impacts on routine activities predicts slower recovery after total knee arthroplasty: an observational study.

Amusat N, Beaupre L, Jhangri GS, Pohar SL, Simpson S, Warren S, Jones CA

Journal of physiotherapy2014

DOI: 10.1016/j.jphys.2014.09.006 PMID: 25443651

Novel protective roles for ATP-sensitive potassium channels in the heart

Co-investigatorCIHR2018Project Grant

Principal investigators: Light, Peter E

Keywords: Electrophysiology; Heart; Heart Failure; Ischemic Heart Disease; Katp Channels; Metabolism; Sulfonylureas

$755,440

International Population-Based Evaluation of Drug Therapies Used to Manage Type 2 Diabetes

Principal investigatorCIHR2012Operating Grant

Principal investigators: Eurich, Dean; Mcalister, Finlay A; Senthilselvan, Ambikaipakan; Simpson, Scot H

Keywords: Cardiovascular System; Diabetes; Health Outcomes; Mortality; Pharmacotherapy; Population Health

$176,644

Is there a dose-response relationship between glyburide and cardiovascular outcomes?

Nominated PICIHR2011Operating Grant

Principal investigators: Simpson, Scot H; Eurich, Dean

Keywords: Cardiovascular Disease; Diabetes; Dose-Response Relationship; Multivariate Cox Proportional Hazards; Population-Based Observational Study; Sulfonylureas (Glyburide); Time-Dependent Drug Exposure

$160,983

The Impact of Drug Exposure Misclassification on Study Estimates of Clinical Outcomes in Administrative Drug Databases

Co-investigatorCIHR2011Operating Grant

Principal investigators: Eurich, Dean

Keywords: Health Outcomes; Pharmacotherapy; Policy; Population Health

$143,425

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Public Health Sciences
Cardiology
Physical Therapy
Geography, Environment and Geomatics
Other

Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Sonia Butalia

Medicine

2 shared papers, latest 2025

Kaberi Dasgupta

Medicine

2 shared papers, latest 2025

Sonia Butalia

Cardiology

2 shared papers, latest 2025

Lauren Beaupre

Physical Therapy

1 shared papers, latest 2014

Aminu Bello

Medicine

1 shared papers, latest 2024

Kaberi Dasgupta

Faculty

1 shared papers, latest 2020

Lorraine Lipscombe

Geography, Environment and Geomatics

1 shared papers, latest 2020

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Paper to mention

Subject: Prospective PhD student: Cardiovascular System Dear Professor Simpson, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Metformin as First-line Therapy: Response to Drs Trinacty and Goldenberg." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]