Faculty profile

Brenda Gerull

ResearcherUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses may be missing. Find their university profile.

Brenda Gerull

Researcher

Health Sciences

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
2 publications in the last five years, latest in 2024.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2012.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

192

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Arrhythmias Arrhythmogenic Right Ventricular Cardiomyopathy Cellular Junction Proteins Disease Mechanisms Genetic Susceptibility Molecular Pathogenesis Mouse Models Phenotypic Variability

Latest papers

Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.
Molecular metabolism · 2024 · senior author
A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients.
Journal of cardiovascular translational research · 2023
Genetic markers of vasovagal syncope.
Autonomic neuroscience : basic & clinical · 2021 · senior author

All 30 publications

Latest funding

Impact of Early Repolarization on Long QT Syndrome: Canadian Genetic Heart Rhythm Network
CIHR · 2015 · Co-investigator
$913,879
Molecular Mechanisms of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) due to Mutations in Cellular Junctions Proteins
CIHR · 2012 · Nominated PI
$439,801

All 2 grants and awards

30 publications.

Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.

Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B

Molecular metabolism2024Senior author

DOI: 10.1016/j.molmet.2023.101859 PMID: 38142971

A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients.

Nagyova E, Hoorntje ET, Te Rijdt WP, Bosman LP, Syrris P, Protonotarios A, Elliott PM, Tsatsopoulou A, Mestroni L, Taylor MRG, Sinagra G, Merlo M, Wada Y, Horie M, Mogensen J, Christensen AH, Gerull B, Song L, Yao Y, Fan S, Saguner AM, Duru F, Koskenvuo JW, Cruz Marino T, Tichnell C, Judge DP, Dooijes D, Lekanne Deprez RH, Basso C, Pilichou K, Bauce B, Wilde AAM, Charron P, Fressart V, van der Heijden JF, van den Berg MP, Asselbergs FW, James CA, Jongbloed JDH, Harakalova M, van Tintelen JP

Journal of cardiovascular translational research2023

DOI: 10.1007/s12265-023-10403-8 PMID: 37418234

Genetic markers of vasovagal syncope.

Sheldon RS, Gerull B

Autonomic neuroscience : basic & clinical2021Senior author

DOI: 10.1016/j.autneu.2021.102871 PMID: 34474354

Generation of two patient-derived iPSC lines from siblings (LIBUCi001-A and LIBUCi002-A) and a genetically modified iPSC line (JMUi001-A-1) to mimic dilated cardiomyopathy with ataxia (DCMA) caused by a homozygous DNAJC19 mutation.

Janz A, Chen R, Regensburger M, Ueda Y, Rost S, Klopocki E, Günther K, Edenhofer F, Duff HJ, Ergün S, Gerull B

Stem cell research2020Senior author

DOI: 10.1016/j.scr.2020.101856 PMID: 32521499

Genetic Animal Models for Arrhythmogenic Cardiomyopathy.

Gerull B, Brodehl A

Frontiers in physiology2020First author

DOI: 10.3389/fphys.2020.00624 PMID: 32670084

A homozygous DSC2 deletion associated with arrhythmogenic cardiomyopathy is caused by uniparental isodisomy.

Brodehl A, Weiss J, Debus JD, Stanasiuk C, Klauke B, Deutsch MA, Fox H, Bax J, Ebbinghaus H, Gärtner A, Tiesmeier J, Laser T, Peterschröder A, Gerull B, Gummert J, Paluszkiewicz L, Milting H

Journal of molecular and cellular cardiology2020

DOI: 10.1016/j.yjmcc.2020.03.006 PMID: 32201174

Restrictive Cardiomyopathy is Caused by a Novel Homozygous Desmin (DES) Mutation p.Y122H Leading to a Severe Filament Assembly Defect.

Brodehl A, Pour Hakimi SA, Stanasiuk C, Ratnavadivel S, Hendig D, Gaertner A, Gerull B, Gummert J, Paluszkiewicz L, Milting H

Genes2019

DOI: 10.3390/genes10110918 PMID: 31718026

The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain.

Perissinotti L, Guo J, Kudaibergenova M, Lees-Miller J, Ol'khovich M, Sharapova A, Perlovich GL, Muruve DA, Gerull B, Noskov SY, Duff HJ

Molecular pharmacology2019

DOI: 10.1124/mol.118.115642 PMID: 31182542

Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy.

Brodehl A, Rezazadeh S, Williams T, Munsie NM, Liedtke D, Oh T, Ferrier R, Shen Y, Jones SJM, Stiegler AL, Boggon TJ, Duff HJ, Friedman JM, Gibson WT, FORGE Canada Consortium, Childs SJ, Gerull B

Translational research : the journal of laboratory and clinical medicine2019

DOI: 10.1016/j.trsl.2019.02.004 PMID: 30802431

Characterization of a Unique Form of Arrhythmic Cardiomyopathy Caused by Recessive Mutation in LEMD2.

Abdelfatah N, Chen R, Duff HJ, Seifer CM, Buffo I, Huculak C, Clarke S, Clegg R, Jassal DS, Gordon PMK, Ober C, Care4Rare Canada Consortium, Frosk P, Gerull B

JACC. Basic to translational science2019

DOI: 10.1016/j.jacbts.2018.12.001 PMID: 31061923

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Brenda Gerull

Research

Latest papers

Latest funding

Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.

A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients.

Genetic markers of vasovagal syncope.

Generation of two patient-derived iPSC lines from siblings (LIBUCi001-A and LIBUCi002-A) and a genetically modified iPSC line (JMUi001-A-1) to mimic dilated cardiomyopathy with ataxia (DCMA) caused by a homozygous DNAJC19 mutation.

Genetic Animal Models for Arrhythmogenic Cardiomyopathy.

A homozygous DSC2 deletion associated with arrhythmogenic cardiomyopathy is caused by uniparental isodisomy.

Restrictive Cardiomyopathy is Caused by a Novel Homozygous Desmin (DES) Mutation p.Y122H Leading to a Severe Filament Assembly Defect.

The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain.

Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy.

Characterization of a Unique Form of Arrhythmic Cardiomyopathy Caused by Recessive Mutation in LEMD2.

Impact of Early Repolarization on Long QT Syndrome: Canadian Genetic Heart Rhythm Network

Molecular Mechanisms of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) due to Mutations in Cellular Junctions Proteins

Frequent collaborators

Shubhayan Sanatani

Jeff Healey

Mario Talajic

Mario Talajic

Vijay Chauhan

Robert Hamilton

Laura Arbour

Christian Steinberg

Robert Sheldon

Martin Green

Sandra Carroll

Jason Roberts

Jorge Wong