Faculty profile

Derya Sargin

ResearcherPsychologyUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses may be missing. Find their university profile.

Derya Sargin

Researcher

Psychology

Health Sciences

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
11 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2025.
Supervised 2 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Serotonin Fiber Photometry Optogenetics Alzheimer'S Disease Dorsal Raphe Nucleus Mouse Models Neuropsychiatric Symptoms Tau

Latest papers

Neurodevelopmental effects of early life stress: PFC and cognition.
Neuroscience and biobehavioral reviews · 2026
Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
An Open-Source and Highly Adaptable Rodent Limited Bedding and Nesting Apparatus for Chronic Early Life Stress.
eNeuro · 2025 · senior author

All 15 publications

Latest funding

Role of hypocretin/orexin neurons in social behaviour and social stress
CIHR · 2025 · Supervisor
$3,000
Unraveling early pathological mechanisms of Alzheimer's disease to develop interventions
CIHR · 2025 · Nominated PI
$1,147,500
Uncovering the role of cerebellar serotonin circuits in a mouse model of Autism Spectrum Disorder
CIHR · 2024 · Supervisor
$210,000

All 8 grants and awards

15 publications.

Neurodevelopmental effects of early life stress: PFC and cognition.

Rachmany L, Abreu F, Walker V, O'Neill O, Sargin D, Teixeira CM

Neuroscience and biobehavioral reviews2026

DOI: 10.1016/j.neubiorev.2026.106663 PMID: 41905562

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.

Rae RJ, Alberhasky JMH, Baillet M, Bangasser DA, Belloy ME, Berry AS, Berteotti C, Bow H, Buckley R, Caldwell JZK, Carpi M, Clark BJ, Ciampa CJ, Conley AC, Dahl MJ, Donaldson ZR, Ehrenberg AJ, Einstein G, Falgàs N, Fenlon HA, Fitzhugh MC, Froemke RC, Gallay C, Grinberg LT, Hamilton DA, Hasan Z, Huarte OU, Jabeen S, Jacobs HIL, Kolling LJ, Koops EA, Lenzoni S, Liguori C, Manca R, Marcinkiewcz CA, Omoluabi T, Oria R, Orsini CA, Ortega NE, Pa J, Pentkowski NS, Pereira JB, Ramos R, Sargin D, Satpati A, Selles MC, Seto M, Shaik SM, Sindi S, Son G, Ucheagwu V, Van Egroo M, Yuan Q, Kelberman MA

Alzheimer's & dementia : the journal of the Alzheimer's Association2026

DOI: 10.1002/alz.71291 PMID: 41853971

An Open-Source and Highly Adaptable Rodent Limited Bedding and Nesting Apparatus for Chronic Early Life Stress.

O'Neill OS, Terstege DJ, Gill AK, Edge-Partington M, Ramkumar R, Epp JR, Sargin D

eNeuro2025Senior author

DOI: 10.1523/eneuro.0081-25.2025 PMID: 40555522

Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease.

Terstege DJ, Ren Y, Ahn BY, Seo H, Adigun K, Alzheimer’s Disease Neuroimaging Initiative, Galea LAM, Sargin D, Epp JR

Science advances2025Senior author

DOI: 10.1126/sciadv.adt8976 PMID: 40305608

SSRIs reduce plasma tau and restore dorsal raphe metabolism in Alzheimer's disease.

Terstege DJ, Jabeen S, Alzheimer's Disease Neuroimaging Initiative, Galea LAM, Epp JR, Sargin D

Alzheimer's & dementia : the journal of the Alzheimer's Association2025

DOI: 10.1002/alz.14579 PMID: 39935329

Long-Term Impact of Early-Life Stress on Serotonin Connectivity.

Ramkumar R, Edge-Partington M, Terstege DJ, Adigun K, Ren Y, Khan NS, Rouhi N, Jamani NF, Tsutsui M, Epp JR, Sargin D

Biological psychiatry2024Senior author

DOI: 10.1016/j.biopsych.2024.01.024 PMID: 38316332

Early-life prefrontal cortex inhibition and early-life stress lead to long-lasting behavioral, transcriptional, and physiological impairments.

Menezes EC, Geiger H, Abreu FF, Rachmany L, Wilson DA, Alldred MJ, Castellanos FX, Fu R, Sargin D, Corvelo A, Teixeira CM

Molecular psychiatry2024

DOI: 10.1038/s41380-024-02499-4 PMID: 38486048

Protocol for the integration of fiber photometry and social behavior in rodent models.

Terstege DJ, Dawson M, Jamani NF, Tsutsui M, Epp JR, Sargin D

STAR protocols2023Senior author

DOI: 10.1016/j.xpro.2023.102689 PMID: 37979176

Hypocretin/orexin neurons encode social discrimination and exhibit a sex-dependent necessity for social interaction.

Dawson M, Terstege DJ, Jamani N, Tsutsui M, Pavlov D, Bugescu R, Epp JR, Leinninger GM, Sargin D

Cell reports2023Senior author

DOI: 10.1016/j.celrep.2023.112815 PMID: 37459234

The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's Disease.

Ren Y, Savadlou A, Park S, Siska P, Epp JR, Sargin D

Frontiers in neuroendocrinology2023Senior author

DOI: 10.1016/j.yfrne.2023.101061 PMID: 36758770

Role of hypocretin/orexin neurons in social behaviour and social stress

SupervisorCIHR2025Travel Awards - Institute Community Support

Principal investigators: Dawson, Matthew K

Keywords: Animal Behaviour; Basic Science; Behavioural Neuroscience; Neuroscience; Social Behaviour; Social Isolation

$3,000

Unraveling early pathological mechanisms of Alzheimer's disease to develop interventions

Nominated PICIHR2025Project Grant

Principal investigators: Sargin, Derya

Keywords: Alzheimer'S Disease; Dorsal Raphe Nucleus; Mouse Models; Neuropsychiatric Symptoms; Serotonin; Tau

$1,147,500

Uncovering the role of cerebellar serotonin circuits in a mouse model of Autism Spectrum Disorder

SupervisorCIHR2024CIHR Fellowship

Principal investigators: Ranjbar, Hoda

Keywords: Autism Spectrum Disorders; Cerebellum; Fiber Photometry; Mouse Models; Serotonin; Serotonin Receptors

$210,000

Parvalbumin Interneuron Dysfunction in the Retrosplenial Cortex of a Mouse Model of Alzheimer's disease

Co-investigatorCIHR2023Project Grant

Principal investigators: Epp, Jonathan R

Keywords: Alzheimer'S Disease; Chemogenetics; Cognitive Impairment; Fiber Photometry; Interneurons; Memory; Mouse Model; Neurodegeneration; Parvalbumin; Retrosplenial Cortex

$765,000

The Role of Orexin/Hypocretin in Isolation-induced Social Deficits

Nominated PICIHR2022Project Grant

Principal investigators: Sargin, Derya

Keywords: Behavioural Neuroscience; Dorsal Raphe; Fiber Photometry; Lateral Hypothalamus; Mouse Model; Neuron Activity; Optogenetics; Orexin/Hypocretin; Social Deficits; Social Isolation

$753,526

Impact of early life stress on brain-wide serotonin circuits and behavioural development

Nominated PICIHR2021Operating Grant: ECI grants in MRC&Y Health - NMHA

Principal investigators: Sargin, Derya

Keywords: Chronic Stress; Depression; Early Life Stress; Electrophysiology; Emotional Behaviour; Fiber Photometry; Neural Circuits; Optogenetics; Serotonin; Social Behaviour

$105,000

Neurobiology of social behaviour

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Sargin, Derya

$165,000

Neurobiology of social behaviour

Principal investigatorNSERC2020Discovery Launch Supplement

Principal investigators: Sargin, Derya

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Derya Sargin

Research

Latest papers

Latest funding

Neurodevelopmental effects of early life stress: PFC and cognition.

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.

An Open-Source and Highly Adaptable Rodent Limited Bedding and Nesting Apparatus for Chronic Early Life Stress.

Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease.

SSRIs reduce plasma tau and restore dorsal raphe metabolism in Alzheimer's disease.

Long-Term Impact of Early-Life Stress on Serotonin Connectivity.

Early-life prefrontal cortex inhibition and early-life stress lead to long-lasting behavioral, transcriptional, and physiological impairments.

Protocol for the integration of fiber photometry and social behavior in rodent models.

Hypocretin/orexin neurons encode social discrimination and exhibit a sex-dependent necessity for social interaction.

The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's Disease.

Role of hypocretin/orexin neurons in social behaviour and social stress

Unraveling early pathological mechanisms of Alzheimer's disease to develop interventions

Uncovering the role of cerebellar serotonin circuits in a mouse model of Autism Spectrum Disorder

Parvalbumin Interneuron Dysfunction in the Retrosplenial Cortex of a Mouse Model of Alzheimer's disease

The Role of Orexin/Hypocretin in Isolation-induced Social Deficits

Impact of early life stress on brain-wide serotonin circuits and behavioural development

Neurobiology of social behaviour

Neurobiology of social behaviour

Frequent collaborators

Gillian Einstein

Gillian Einstein

Judy Illes

Yves De Koninck

Qi Yuan

Caroline Menard