This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma.
Genome biology · 2024
Natural killer T cell immunotherapy combined with oncolytic vesicular stomatitis virus or reovirus treatments differentially increases survival in mouse models of ovarian and breast cancer metastasis.
Journal for immunotherapy of cancer · 2021
Antirelapse effect of pretransplant exposure to rabbit antithymocyte globulin.
Blood advances · 2019
Latest funding
- $120,000
Investigating the therapeutic potential of CD4-targeted CAR-double negative T cells in acute myeloid leukemia
CIHR · 2025 · Supervisor
- $120,000
VIVO-EDIT: In Vivo Engineering of Multiplex-Edited CAR-T Cells Using Virus-Like Particles for Cancer Immunotherapy
CIHR · 2025 · Supervisor
- $120,000
Investigating the role and function of type 2 innate lymphoid cells during PD-1 blockade
CIHR · 2024 · Supervisor
3 publications.
Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma.
Manoharan VT, Abdelkareem A, Gill G, Brown S, Gillmor A, Hall C, Seo H, Narta K, Grewal S, Dang NH, Ahn BY, Osz K, Lun X, Mah L, Zemp F, Mahoney D, Senger DL, Chan JA, Morrissy AS
Natural killer T cell immunotherapy combined with oncolytic vesicular stomatitis virus or reovirus treatments differentially increases survival in mouse models of ovarian and breast cancer metastasis.
Gebremeskel S, Nelson A, Walker B, Oliphant T, Lobert L, Mahoney D, Johnston B
Antirelapse effect of pretransplant exposure to rabbit antithymocyte globulin.
Dabas R, Jamani K, Kangarloo SB, Dharmani-Khan P, Williamson TS, Ousia S, Durand C, Morris D, Mahoney D, Savoie L, Chaudhry A, Jimenez-Zepeda VH, Khan FM, Daly A, Storek J
Investigating the therapeutic potential of CD4-targeted CAR-double negative T cells in acute myeloid leukemia
Principal investigators: Wang, Shanshan
Keywords: Acute Myeloid Leukemia; Adoptive Cellular Therapy; Animal Models; Cancer Immunology; Chimeric Antigen Receptor (Car)-T Cell Therapy; Double Negative T Cells; Immunotherapy; Novel Cancer Therapies
VIVO-EDIT: In Vivo Engineering of Multiplex-Edited CAR-T Cells Using Virus-Like Particles for Cancer Immunotherapy
Principal investigators: Langley, Jethro
Keywords: Cancer Therapies; Car-T Cell Therapy; Crispr Technologies; Genome Editing; Immune Cell Engineering; In Vivo Genome Editing; Leukemia; Synthetic Biology; Viral Vectors; Virus-Like Particles
Investigating the role and function of type 2 innate lymphoid cells during PD-1 blockade
Principal investigators: Seo, Hobin
Keywords: Animal Models; Canadian Cancer Research; Cancer Immunology; Immune Checkpoint Blockade; Immunotherapy; Innate And Adaptive Immunity; Novel Cancer Therapies; Pd-1; Spectral Flow Cytometry; Type 2 Innate Lmyphoid Cells
Determining the role of the microbiome and microbial metabolites in enhancing the efficacy of CD19 directed CAR-T cell therapy of B cell malignancies.
Principal investigators: McCoy, Kathy
Keywords: Acute Lymphoblastic Leukemia; Anti-Tumor Immunity; Chimeric Antigen Receptor (Car)-T Cells; Gnotobiotic Mouse Models; Human Microbiome Associated Mice; Immunotherapy; Inosine; Metabolites; Microbiome
A Phase I Feasibility and Safety Study of GCAR1, a Chimeric Antigen Receptor (CAR) T-cell Therapy for Patients with Relapsed/Refractory GPNMB-Expressing Solid Tumors
Principal investigators: Shafey, Mona; Abdul Razak, Albiruni R; Hay, Kevin A; Henning, Jan-Willem; Kekre, Natasha; Mahoney, Douglas J; Morrissy, Sorana A; Noujaim, Jonathan; Simmons, Christine E
Keywords: Alveolar Soft Part Sarcoma; Car T; Immunotherapy; Renal Cell Carcinoma; Sarcoma; Triple-Negative Breast Cancer
A systematic approach to understand the mechanism of immune cell infiltration and to enhance efficacy of immunotherapy in solid tumors
Principal investigators: Li, Lin
Keywords: Anti-Pd1 Therapy; Bioinformatics; Crispr; Hot And Cold Tumor; Immune Cell Infiltration; Immunotherapy; Single Cell Sequencing; Syngeneic Mouse Model
Characterizing the mechanisms by which oncolytic viruses induce antitumour immunity
Principal investigators: Rajwani, Jahanara
Keywords: Anticancer T Cells; Cancer Immunotherapy; Host-Virus Interactions; Oncolytic Viruses; Rhabdoviruses
Mechanisms underlying oncolytic rhabdovirus-mediated anticancer immunity
Principal investigators: Mahoney, Douglas J
Keywords: Cancer; Immunotherapy; Intravital Microscopy; Oncolytic Viruses; Rhabdovirus
5T4-CAR-NKT cell therapy for pediatric rhabdomyosarcoma
Principal investigators: Gebremeskel, Simon Y
Keywords: Cancer; Car T Cells; Immunotherapy; Oncolytic Virus Therapy; Rhabdomyosarcoma; Tumor Antigen
Oncolytic rhabdovirus vaccines as an adjuvant to adoptive T cell therapy for paediatric metastatic rhabdomyosarcomas: Precision targeting, expansion and trafficking
Principal investigators: Zemp, Franz J
Keywords: Cancer; Immunology; Immunotherapy; Oncolytic Viruses; Paediatric Cancer
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.