Faculty profile
Laura Sycuro
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Research
Latest papers
Exploring the Early-Life Microbiomes of Preterm Infants and Their Childhood Health Outcomes (The BLOOM Study): Protocol for a Prospective, Observational Cohort Study.
JMIR research protocols · 2026
Assessment of HBV variants and novel viral and immune biomarkers in chronic hepatitis B patients with metabolic dysfunction associated steatotic liver disease.
Journal of viral hepatitis · 2024
Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women.
BMJ open · 2023
Latest funding
- $120,000
Fetal fibronectin: deciphering its cryptic connection to the vaginal microbiome and preterm birth
CIHR · 2024 · Supervisor
- $1,036,576
A systems-level framework for discovering microbiome proteases and their capacity to manipulate homeostasis and barrier function in the female genital tract
CIHR · 2024 · Nominated PI
- $12,500
Life on the inside: Defining the adhesion and invasion behaviours of human microbiota
NSERC · 2023 · Principal investigator
4 publications.
Exploring the Early-Life Microbiomes of Preterm Infants and Their Childhood Health Outcomes (The BLOOM Study): Protocol for a Prospective, Observational Cohort Study.
Asbury MR, Guedez A, Lee J, Mercer EM, Kasaba F, Rangipour Z, Kellner JD, Lacaze-Masmonteil T, Samara J, Leijser LM, Lebel C, Zein H, Hendson L, Murguía Favela L, McNagny K, Giesbrecht GF, Sycuro L, Alshaikh B, Arrieta MC
Assessment of HBV variants and novel viral and immune biomarkers in chronic hepatitis B patients with metabolic dysfunction associated steatotic liver disease.
Patel NH, Lucko A, Vachon A, Doucette KE, Ramji A, Sycuro L, Patel TR, Chadee K, Raman M, van Marle G, Osiowy C, Coffin CS
Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women.
Oluoch L, Tapia K, Kiptinness C, Casmir E, Maina SG, Makena L, Selke S, Wang M, Chohan B, Sycuro L, Wald A, Ngure K, Mugo N, Roxby A
Low prevalence of bacterial vaginosis in Kenyan adolescent girls and rapid incidence after first sex.
Roxby AC, Mugo NR, Oluoch LM, Tapia K, Wang M, Selke S, Chohan B, Micheni M, Sycuro L, Yuh T, Casmir E, Kimani E, Maina SG, Kiptinness C, Ngure K, Wald A
Fetal fibronectin: deciphering its cryptic connection to the vaginal microbiome and preterm birth
Principal investigators: Birse, Kenzie
Keywords: Bacterial Vaginosis; Bacteriology; Cell Culture; Fetal Fibronectin; Inflammation; Pregnancy; Preterm Birth; Proteomics; Vaginal Microbiome
A systems-level framework for discovering microbiome proteases and their capacity to manipulate homeostasis and barrier function in the female genital tract
Principal investigators: Sycuro, Laura K; Dufour, Antoine
Keywords: Bacterial Virulence; Genital Tract Mucosa; Innate Immunity; Metaproteomics; Metatranscriptomics; Multi-Omics; Proteases; Synthetic Biology; Systems Biology; Vaginal Microbiome
Life on the inside: Defining the adhesion and invasion behaviours of human microbiota
Principal investigators: Sycuro, Laura
Elucidating the role of the vaginal microbiome in pathological tissue remodeling associated with pelvic organ prolapse
Principal investigators: Sycuro, Laura
Keywords: female urogenital tract; proteomics; activity-based probes; 2D human organoids; vaginal microbiome; degradomics; extracellular matrix; pelvic organ prolapse; proteases; glycosaminoglycans
Proteases from vaginal Prevotella species as key drivers of endocervical susceptibility to HIV infection
Principal investigators: Lithgow, Karen V
Keywords: Bacterial Vaginosis; Hiv; Human Cell Culture; Protease Activity; Proteomics; Sexually Transmitted Infections; Vaginal Microbiome
Life on the inside: Defining the adhesion and invasion behaviours of human microbiota
Principal investigators: Sycuro, Laura
Keywords: bacterial adhesion; cell culture models; fluorescence microscopy; functional genomics; host-microbe interactions; human microbiota; intracellular invasion; phylogenetics; protein domain architecture; synthetic biology
Defining the role of proteolysis in genital tract infections: from pathways to novel enzymes
Principal investigators: Sycuro, Laura K; Dufour, Antoine
Keywords: Bacterial Virulence Activities; Genital Tract Infection; Metagenomics; Metaproteomics; Proteases; Vaginal Microbiome
Microbial modification of the cervicovaginal glycome as a risk factor for chlamydia
Principal investigators: Sycuro, Laura K; Ugarte Torres, Alejandra
Keywords: Adolescent Sti; Chlamydia; Glycomics; Metagenomics; Multilayer Cell Culture Model; Sialidase; Vaginal Microbiome
Contribution of the microbiome to asthma risk in premature infants
Principal investigators: Arrieta Mendez, Marie-Claire; Azad, Meghan; Giesbrecht, Gerald F; Kembel, Steven W; Kozyrskyj, Anita L; Langille, Morgan G; McNagny, Kelly M; Sycuro, Laura K
Keywords: Asthma; Early-Life Microbiome; Gut Microbiome; Prematurity; Systems Biology
Integrated Microbiome Platforms for Advancing Causation Testing and Translation (IMPACTT)
Principal investigators: McCoy, Kathy; Arrieta Mendez, Marie-Claire; Beiko, Robert G; Brinkman, Fiona S; Geuking, Markus; Gros, Philippe; Harrison, Joe J; Kozyrskyj, Anita L; Kubes, Paul; Langille, Morgan G; Lewis, Ian A; Madsen, Karen L; Silva, Diego S; Sycuro, Laura K; Wine, Eytan
Keywords: Computational Tools And Analysis; Functional Studies; Gnotobiotic Animal Models; Host-Microbe Interactions; Human Cohort Linkage; Microbial Repositories; Microbiome; Omics Platforms; Research Core; Standardized Protocols
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Kelly McNagny and Catherine Lebel: 1 shared paper
- Kelly McNagny and Laura Sycuro: 1 shared paper
- Kelly McNagny and Thierry Lacaze-Masmonteil: 1 shared paper
- Kelly McNagny and Belal Alshaikh: 1 shared paper
- Catherine Lebel and Laura Sycuro: 1 shared paper
- Catherine Lebel and Thierry Lacaze-Masmonteil: 1 shared paper
- Catherine Lebel and Belal Alshaikh: 1 shared paper
- Laura Sycuro and Thierry Lacaze-Masmonteil: 1 shared paper
- Laura Sycuro and Guido van Marle: 1 shared paper
- Laura Sycuro and Belal Alshaikh: 1 shared paper
- Microbiology and Infectious Diseases
- Pediatrics
- Radiology
- Biochemistry and Molecular Biology
- Biomedical Engineering
- Physiology and Pharmacology
Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Thierry Lacaze-Masmonteil
Physiology and Pharmacology
1 shared papers, latest 2026
Guido van Marle
Biochemistry and Molecular Biology
1 shared papers, latest 2024
Belal Alshaikh
Pediatrics
1 shared papers, latest 2026
Kelly McNagny
Biomedical Engineering
1 shared papers, latest 2026
Catherine Lebel
Radiology
1 shared papers, latest 2026
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