Michael Monument, University of Calgary

Research

Mouse Models Sarcoma Cancer Gene Therapy Immunotherapy Stimulator Of Interferon Genes (Sting)Tumour Microenvironment Car T Immunotherapy

Latest papers

GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors.
Nature cancer · 2026
MDM2 analysis in the management of benign lipomas versus atypical lipomatous tumors/well-differentiated liposarcomas: A useful prognostication tool?
American journal of surgery · 2022
What Are the Long-term Surgical Outcomes of Compressive Endoprosthetic Osseointegration of the Femur with a Minimum 10-year Follow-up Period?
Clinical orthopaedics and related research · 2022

All 6 publications

Latest funding

Conditioning the Tumor and Empowering the Cell: A New Paradigm for CAR T Therapy in Soft Tissue Sarcomas
CIHR · 2026 · Nominated PI
$1,181,926
STING Activation in Sarcoma: Assessing Translational Therapeutic Strategies
CIHR · 2022 · Supervisor
$105,000
Evaluating Individual Cancer-associated Thrombosis Mechanisms to Inform Personalized Thromboprophylaxis in Patients with Metastatic Bone Disease
CIHR · 2022 · Co-investigator
$100,000

All 7 grants and awards

6 publications.

01

GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors.

Zemp FJ, Breckenridge Z, Song H, Gill GS, Louie TL, Narta K, Liu H, Suh Y, Guignard L, Mandujano-Tinoco EA, Collao N, Pyczek J, Ellestad KK, Curry J, Langley J, John C, Mah LK, Rajwani J, Evseev D, Turk M, Benaoudia S, Alex J, Naumenko V, Manoharan VT, Mehrabadi MK, Smith HA, Gilbert GNY, Gillmor A, Verhey TB, Todesco HM, Osz K, Ahn BY, Bogossian A, Anderson C, Sikdar S, Rukunuddin S, Bismar TA, Heng DYC, Lawson K, Linehan WM, Pedersen H, Gordon PMK, McIntyre JB, MacGregor J, Garzia L, Brodeur-Robb K, DiFrancesco L, Ogilvie T, Schöffski P, Wozniak A, Holt RA, Bell J, Senger DL, Lewis V, Monument M, Khan O, Baudrier L, Billon P, Gabriel V, Biernaskie J, Potts K, Trpkov K, Hay K, Quizi J, Chan J, Saleh R, Henning JW, Prokopishyn NL, Shafey M, Morrissy AS, Mahoney DJ

Nature cancer2026

DOI: 10.1038/s43018-026-01194-3 PMID: 42387022

02

MDM2 analysis in the management of benign lipomas versus atypical lipomatous tumors/well-differentiated liposarcomas: A useful prognostication tool?

Choi KY, Mack L, Caragea M, Monument M, Puloski S, Bouchard-Fortier A

American journal of surgery2022

DOI: 10.1016/j.amjsurg.2022.03.052 PMID: 35397923

03

What Are the Long-term Surgical Outcomes of Compressive Endoprosthetic Osseointegration of the Femur with a Minimum 10-year Follow-up Period?

Groundland J, Brown JM, Monument M, Bernthal N, Jones KB, Randall RL

Clinical orthopaedics and related research2022

DOI: 10.1097/corr.0000000000001979 PMID: 34559734

04

Intraoperative Near-infrared Spectroscopy Correlates with Skin Flap Necrosis: A Prospective Cohort Study.

Hill WF, Webb C, Monument M, McKinnon G, Hayward V, Temple-Oberle C

Plastic and reconstructive surgery. Global open2020

DOI: 10.1097/gox.0000000000002742 PMID: 32440412

05

Mortality in a low energy geriatric polytrauma patient.

Kubik J, Monument M, Buckley R

Trauma case reports2019

DOI: 10.1016/j.tcr.2019.100258 PMID: 31768413

06

Surgical excision versus observation as initial management of desmoid tumors: A population based study.

Turner B, Alghamdi M, Henning JW, Kurien E, Morris D, Bouchard-Fortier A, Schiller D, Puloski S, Monument M, Itani D, Mack LA

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology2019

DOI: 10.1016/j.ejso.2018.09.015 PMID: 30420189

Conditioning the Tumor and Empowering the Cell: A New Paradigm for CAR T Therapy in Soft Tissue Sarcomas

Nominated PICIHR2026Project Grant

Principal investigators: Monument, Michael J

Keywords: Car T Immunotherapy; Mouse Models; Sarcoma; Single Cell Rna Sequencing; Sting Immunotherapy; Tumor Radiation

$1,181,926

STING Activation in Sarcoma: Assessing Translational Therapeutic Strategies

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Hildebrand, Karys M

Keywords: Gene Therapy; Immunotherapy; Soft Tissue Sarcoma; Stimulator Of Interferon Genes Pathway; Undifferentiated Pleomorphic Sarcoma

$105,000

Evaluating Individual Cancer-associated Thrombosis Mechanisms to Inform Personalized Thromboprophylaxis in Patients with Metastatic Bone Disease

Co-investigatorCIHR2022Project Grant - PA: Patient-Oriented Research: Early-Career Investigator

Principal investigators: Schneider, Prism S

Keywords: Cancer-Related Thrombosis; Deep Vein Thrombosis; Point-Of-Care Diagnostic Tool; Precision Medicine; Pulmonary Embolism; Thrombelastography; Thromboprophylaxis; Trauma-Induced Coagulopathy; Venous Thromboembolism

$100,000

Evaluating Individual Cancer-associated Thrombosis Mechanisms to Inform Personalized Thromboprophylaxis in Patients with Metastatic Bone Disease

Co-investigatorCIHR2022Project Grant

Principal investigators: Schneider, Prism S

Keywords: Cancer-Related Thrombosis; Deep Vein Thrombosis; Point-Of-Care Diagnostic Tool; Precision Medicine; Pulmonary Embolism; Thrombelastography; Thromboprophylaxis; Trauma-Induced Coagulopathy; Venous Thromboembolism

$1,043,615

Early Career Award in Cancer: Harnessing STING activation for the treatment of sarcoma

Nominated PICIHR2020PRIZE - Project Grant - PA: Prize: Early Career Investigator in Cancer

Principal investigators: Monument, Michael J

Keywords: Cancer; Gene Therapy; Immunotherapy; Mouse Models; Sarcoma; Stimulator Of Interferon Genes (Sting); Tumour Microenvironment

$25,000

Harnessing STING activation for the treatment of sarcoma

Nominated PICIHR2020Project Grant

Principal investigators: Monument, Michael J

Keywords: Cancer; Gene Therapy; Immunotherapy; Mouse Models; Sarcoma; Stimulator Of Interferon Genes (Sting); Tumour Microenvironment

$1,071,000

Surgical Decision Making in the Management of Metastatic Bone Disease: Matching Patient Expectations with Surgical Goals

Nominated PICIHR2017Patient-Oriented Research Collaboration Grants - New/Early Career Investigators

Principal investigators: Monument, Michael J; Puloski, Shannon K

Keywords: Focus Groups; Metastatic Bone Disease; Patient Goals And Expectations; Patient Outcomes; Patient-Oriented Research; Qualitative Research; Quality Of Life; Surgical Decision Making

$40,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Surgery
Orthopedic Surgery
Oncology
Pathology and Laboratory Medicine
Biochemistry, Microbiology and Immunology
Biochemistry and Molecular Biology
Other

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Shannon Puloski

Orthopedic Surgery

2 shared papers, latest 2022

Livia Garzia

Faculty

1 shared papers, latest 2026

Ramy Saleh

Medicine

1 shared papers, latest 2026

Jennifer Quizi

Faculty

1 shared papers, latest 2026

Victor Lewis

Pediatrics

1 shared papers, latest 2026

Mona Shafey

Medicine

1 shared papers, latest 2026

Kevin Hay

Medicine

1 shared papers, latest 2026

Jan-Willem Henning

Medicine

1 shared papers, latest 2019

Pierre Billon

Biochemistry and Molecular Biology

1 shared papers, latest 2026

John Bell

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2026

Jennifer Chan

Pathology and Laboratory Medicine

1 shared papers, latest 2026

Elizabeth Kurien

Oncology

1 shared papers, latest 2019

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2026

Subject: Prospective PhD student: Mouse Models Dear Professor Monument, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Conditioning the Tumor and Empowering the Cell: A New Paradigm for CAR T Therapy in Soft Tissue Sarcomas" (2026), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]