Faculty profile

Lawrence McCandless

ResearcherSimon Fraser University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Simon Fraser University directory, so their courses and email address may be missing. Find their university profile.

Lawrence McCandless

Researcher

Health Sciences

Simon Fraser University

Burnaby, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
11 publications in the last five years, latest in 2026.
Principal investigator on 5 research grants (3 NSERC, 2 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

108

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Biostatistics Epidemiology Environmental Contaminants Environmental Influences On Health Machine Learning Pregnancy Outcomes Preterm Birth Bayesian Statistics

Latest papers

Comparative effectiveness of alternative times to opioid agonist treatment taper initiation on taper completion and all-cause mortality among people with opioid use disorder: A retrospective population-based target trial emulation study in British Columbia, Canada, 2010-2020.
Addiction (Abingdon, England) · 2026
Joint associations between gestational environmental chemical mixtures and child behavioral outcomes.
Environment international · 2026
Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population-Based Study.
Arthritis & rheumatology (Hoboken, N.J.) · 2026

All 23 publications

Latest funding

Team British Columbia [I-HeLTI NUU-CHAH-NULTH TRIBAL COUNCIL], of Indigenous Healthy Life Trajectory Initiative (I-HeLTI)
CIHR · 2025 · Co-investigator
$408,333
A Randomized Air Cleaner Intervention Study of Particulate Air Pollution, Fetal Growth, and Early Childhood Development
CIHR · 2025 · Co-investigator
$100,000
Hishuk-ish tsawalk (everything is one, everything is connected): Restoring healthy family systems in Indigenous communities
CIHR · 2022 · Co-investigator
$14,100,000

All 13 grants and awards

23 publications.

Comparative effectiveness of alternative times to opioid agonist treatment taper initiation on taper completion and all-cause mortality among people with opioid use disorder: A retrospective population-based target trial emulation study in British Columbia, Canada, 2010-2020.

Yan R, Min JE, Kurz M, Seaman SR, Bach P, Greenland S, Gustafson P, Karim ME, McCandless L, Platt RW, Siebert U, Socías ME, Xie H, Nosyk B

Addiction (Abingdon, England)2026

DOI: 10.1111/add.70489 PMID: 42227316

Joint associations between gestational environmental chemical mixtures and child behavioral outcomes.

Puvvula J, Hwang WT, McCandless L, Xie C, Braun JM, Vuong AM, Schisterman EF, Shinohara RT, Oulhote Y, Booij L, Séguin JR, Bouchard MF, Till C, Zidek A, Borghese MM, Fisher M, Fraser WD, Muckle G, Yolton K, Cecil KM, Ashley-Martin J, Arbuckle TE, Lanphear B, Chen A

Environment international2026

DOI: 10.1016/j.envint.2026.110383 PMID: 42365676

Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population-Based Study.

Hoque MR, Lacaille D, Aviña-Zubieta JA, De Vera MA, Qian Y, McCandless L, Esdaile JM, Xie H

Arthritis & rheumatology (Hoboken, N.J.)2026

DOI: 10.1002/art.70071 PMID: 41657297

Sudden cardiac death in adults living with HIV: A systematic review.

Pierzchalski J, Cunnigham N, Kooij K, Guillemi S, Smith R, McCandless L, Hogg R

PloS one2025

DOI: 10.1371/journal.pone.0334718 PMID: 41166354

Comparative effectiveness of take-home dosing schedules for opioid agonist treatment in British Columbia, Canada: a target trial emulation protocol using a population-based observational study.

Kurz M, Guerra-Alejos BC, Hossain MB, Min JE, Yan R, Bruneau J, Catherine NLA, Greenland S, Gustafson P, Hedden L, Karim E, McCandless L, Nolan S, Platt RW, Bach P, Seaman S, Siebert U, Socías ME, Nosyk B

BMJ open2025

DOI: 10.1136/bmjopen-2024-098317 PMID: 41093336

Comparative effectiveness of methadone take-home dose initiation in British Columbia, Canada: protocol for a population-based retrospective cohort study using target trial guidelines.

Hossain MB, Guerra-Alejos BC, Kurz M, Min JE, Karim ME, Seaman S, Bach P, Platt RW, Gustafson P, Bruneau J, McCandless L, Socías ME, Nosyk B

BMJ open2025

DOI: 10.1136/bmjopen-2024-095198 PMID: 40044208

Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts.

Puvvula J, Hwang WT, McCandless L, Xie C, Braun JM, Vuong AM, Oulhote Y, Schisterman EF, Shinohara RT, Booij L, Bouchard MF, Linn K, Borghese MM, Seguin JR, Zidek A, Till C, Fraser W, Yolton K, Cecil KM, Ashley-Martin J, Arbuckle TE, Lanphear B, Chen A

Environment international2025

DOI: 10.1016/j.envint.2025.109298 PMID: 39893913

What is the ideal time to begin tapering opioid agonist treatment? A protocol for a retrospective population-based comparative effectiveness study in British Columbia, Canada.

Yan R, Kurz M, Guerra-Alejos BC, Min JE, Bach P, Greenland S, Gustafson P, Karim E, Korthuis PT, Loughin T, McCandless L, Platt RW, Schnepel K, Seaman S, Socías ME, Wood E, Xie H, Nosyk B

BMJ open2024

DOI: 10.1136/bmjopen-2023-083453 PMID: 38684262

Comparative Analysis of Instrumental Variables on the Assignment of Buprenorphine/Naloxone or Methadone for the Treatment of Opioid Use Disorder.

Homayra F, Enns B, Min JE, Kurz M, Bach P, Bruneau J, Greenland S, Gustafson P, Karim ME, Korthuis PT, Loughin T, MacLure M, McCandless L, Platt RW, Schnepel K, Shigeoka H, Siebert U, Socias E, Wood E, Nosyk B

Epidemiology (Cambridge, Mass.)2024

DOI: 10.1097/ede.0000000000001697 PMID: 38290142

Antimalarial Adherence and Risk of Cardiovascular Events in Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population-Based Study.

Hoque MR, Aviña-Zubieta JA, Lacaille D, De Vera MA, Qian Y, McCandless L, Esdaile JM, Xie H

Arthritis care & research2024

DOI: 10.1002/acr.25233 PMID: 37691305

Team British Columbia [I-HeLTI NUU-CHAH-NULTH TRIBAL COUNCIL], of Indigenous Healthy Life Trajectory Initiative (I-HeLTI)

Co-investigatorCIHR2025Directed Grant: Supplement to the I-HeLTI Teams

Principal investigators: Lucas, Lynnette J; Nepomnaschy, Pablo A; Reading, Jeffrey L; Venners, Scott; Watts, Jeannette C

Keywords: Cardio-Metabolic Conditions; Child Development; Child Health; Developmental Origins Of Health And Disease; Indigenous Health; Interventions; Mental Health; Peri-Conceptional Cohort; Program Evaluation; Two-Eyed Seeing

$408,333

A Randomized Air Cleaner Intervention Study of Particulate Air Pollution, Fetal Growth, and Early Childhood Development

Co-investigatorCIHR2025Project Grant - PA: Population and Public Health - Global Public Health

Principal investigators: Allen, Ryan; Cantoral Preciado, Alejandra D

Keywords: Air Pollution; Fetal Growth; Intervention; Neurodevelopment; Pregnancy

$100,000

Hishuk-ish tsawalk (everything is one, everything is connected): Restoring healthy family systems in Indigenous communities

Co-investigatorCIHR2022Team Grant: I-HeLTI Cohort Research Study

Principal investigators: Lucas, Lynnette J; Bell, Rhonda C; Bill, Lea; Montesanti, Stephanie R; Nepomnaschy, Pablo A; Oster, Richard T; Reading, Jeffrey L; Titone, Sebastien; Venners, Scott; Waddell, Charlotte A; Watts, Jeannette C

Keywords: Child Development; Dohad; Indigenous Health; Life Course; Maternal And Child Health; Non-Communicable Diseases; Nutrition; Resilience; Social And Biological Determinants Of Health And Development; Stress And Trauma

$14,100,000

Bayesian causal inference for environmental epidemiology data

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: McCandless, Lawrence

$72,000

Hishuk-ish tsawalk (everything is one, everything is connected): Using two-eyed seeing to optimize healthy early life trajectories for Indigenous Peoples

Co-investigatorCIHR2019Team Grant: Indigenous Component of Healthy Life Trajectories (I-HeLTI)

Principal investigators: Lucas, Lynnette J; Nepomnaschy, Pablo A; Reading, Jeffrey L; Venners, Scott; Waddell, Charlotte A; Watts, Jeannette C

$1,012,500

An intervention study of prenatal air pollution exposure and its impacts on cardiometabolic and respiratory health in children

Co-investigatorCIHR2019Project Grant

Principal investigators: Allen, Ryan

Keywords: Air Pollution; Asia; Developmental Programming; Dohad; Environmental Health; Intervention; Pregnancy; Prenatal

$699,976

Improving Experiences and Outcomes for Patients with Schizophrenia Following Involvement with the Justice System: Proposal to Develop a Randomized Registry Trial

Co-investigatorCIHR2016Catalyst Grant: SPOR Innovative Clinical Trials (iCT)

Principal investigators: Somers, Julian; Clark, Elenore; Procyshyn, Ric M; Ross, Colin A

Keywords: Drug Effectiveness; Public Safety; Randomized Registry Trial; Schizophrenia

$89,220

Biostatistical methods for estimating the cumulative impact of environmental contaminant exposures on preterm birth

Nominated PICIHR2016Catalyst Grant: Catalyzing Innovation in Preterm Birth Research

Principal investigators: McCandless, Lawrence; Lanphear, Bruce P

Keywords: Biostatistics; Environmental Contaminants; Environmental Influences On Health; Epidemiology; Machine Learning; Pregnancy Outcomes; Preterm Birth

$198,330

Bayesian bias modelling for causal inference in statistics

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: McCandless, Lawrence

$85,000

Prenatal exposure to environmental contaminants and fetal growth: How to account for multiplicity when testing multiple statistical hypotheses?

Nominated PICIHR2015Planning and Dissemination Grant - Institute Community Support

Principal investigators: McCandless, Lawrence; Lanphear, Bruce P

Keywords: Bayesian Statistics; Biostatistics; Epidemiology; Fetal Growth; Multiple Comparisons

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2021

Subject: Prospective PhD student: Biostatistics Dear Professor McCandless, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Comparative effectiveness of alternative times to opioid agonist treatment taper initiation on taper completion and all-cause mortality among people with opioid use disorder: A retrospective population-based target trial emulation study in British Columbia, Canada, 2010-2020." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Bayesian causal inference for environmental epidemiology data" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Lawrence McCandless

Research

Latest papers

Latest funding

Comparative effectiveness of alternative times to opioid agonist treatment taper initiation on taper completion and all-cause mortality among people with opioid use disorder: A retrospective population-based target trial emulation study in British Columbia, Canada, 2010-2020.

Joint associations between gestational environmental chemical mixtures and child behavioral outcomes.

Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population-Based Study.

Sudden cardiac death in adults living with HIV: A systematic review.

Comparative effectiveness of take-home dosing schedules for opioid agonist treatment in British Columbia, Canada: a target trial emulation protocol using a population-based observational study.

Comparative effectiveness of methadone take-home dose initiation in British Columbia, Canada: protocol for a population-based retrospective cohort study using target trial guidelines.

Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts.

What is the ideal time to begin tapering opioid agonist treatment? A protocol for a retrospective population-based comparative effectiveness study in British Columbia, Canada.

Comparative Analysis of Instrumental Variables on the Assignment of Buprenorphine/Naloxone or Methadone for the Treatment of Opioid Use Disorder.

Antimalarial Adherence and Risk of Cardiovascular Events in Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population-Based Study.

Bayesian causal inference for environmental epidemiology data

Bayesian bias modelling for causal inference in statistics

Frequent collaborators

Bohdan Nosyk

Paxton Bach

Bohdan Nosyk

Michael Boyle

Susan Jack

Andrea Gonzalez

Harriet MacMillan

Charlotte Waddell

Julie Bruneau

Diane Lacaille

Linda Booij

Bruce Lanphear

Linda Booij

Christine Till

Linda Booij

Evan Wood

Colleen Varcoe

Amiram Jacob Gafni

Angela Kaida

Lindsay Hedden

Robert Hogg

James Scott

Mandy Fisher

Lindsay Hedden

Andrea Gonzalez

Seonaid Nolan

Gina Muckle

Padmaja Subbarao

Malcolm Sears

Russell de Souza

Robert Hogg

Padmaja Subbarao

William Fraser