Faculty profile
Peter Ruben
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Latest papers
Functional Genomics of Epilepsy and Associated Neurodevelopmental Disorders Using Simple Animal Models: From Genes, Molecules to Brain Networks.
Frontiers in cellular neuroscience · 2019
Voltage gated sodium channels in cancer and their potential mechanisms of action.
Channels (Austin, Tex.) · 2019 · senior author
Compound heterozygous TRPV4 mutations in two siblings with a complex phenotype including severe intellectual disability and neuropathy.
American journal of medical genetics. Part A · 2017
Latest funding
- $252,000
Modulation of sodium channel gating
NSERC · 2018 · Principal investigator
- $25,000
Tracking the fate of TTX-bound sodium channels.
NSERC · 2014 · Principal investigator
- $204,000
Coevolution of tetrodotoxin and voltage-gated sodium channels
NSERC · 2012 · Principal investigator
5 publications.
Functional Genomics of Epilepsy and Associated Neurodevelopmental Disorders Using Simple Animal Models: From Genes, Molecules to Brain Networks.
Rosch R, Burrows DRW, Jones LB, Peters CH, Ruben P, Samarut É
Voltage gated sodium channels in cancer and their potential mechanisms of action.
Angus M, Ruben P
Compound heterozygous TRPV4 mutations in two siblings with a complex phenotype including severe intellectual disability and neuropathy.
Thibodeau ML, Peters CH, Townsend KN, Shen Y, Hendson G, Adam S, Selby K, Macleod PM, Gershome C, Ruben P, Jones SJM, FORGE Canada Consortium, Friedman JM, Gibson WT, Horvath GA
Exome Sequencing and the Management of Neurometabolic Disorders.
Tarailo-Graovac M, Shyr C, Ross CJ, Horvath GA, Salvarinova R, Ye XC, Zhang LH, Bhavsar AP, Lee JJ, Drögemöller BI, Abdelsayed M, Alfadhel M, Armstrong L, Baumgartner MR, Burda P, Connolly MB, Cameron J, Demos M, Dewan T, Dionne J, Evans AM, Friedman JM, Garber I, Lewis S, Ling J, Mandal R, Mattman A, McKinnon M, Michoulas A, Metzger D, Ogunbayo OA, Rakic B, Rozmus J, Ruben P, Sayson B, Santra S, Schultz KR, Selby K, Shekel P, Sirrs S, Skrypnyk C, Superti-Furga A, Turvey SE, Van Allen MI, Wishart D, Wu J, Wu J, Zafeiriou D, Kluijtmans L, Wevers RA, Eydoux P, Lehman AM, Vallance H, Stockler-Ipsiroglu S, Sinclair G, Wasserman WW, van Karnebeek CD
Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or 'classical' congenital myopathy.
Zaharieva IT, Thor MG, Oates EC, van Karnebeek C, Hendson G, Blom E, Witting N, Rasmussen M, Gabbett MT, Ravenscroft G, Sframeli M, Suetterlin K, Sarkozy A, D'Argenzio L, Hartley L, Matthews E, Pitt M, Vissing J, Ballegaard M, Krarup C, Slørdahl A, Halvorsen H, Ye XC, Zhang LH, Løkken N, Werlauff U, Abdelsayed M, Davis MR, Feng L, Phadke R, Sewry CA, Morgan JE, Laing NG, Vallance H, Ruben P, Hanna MG, Lewis S, Kamsteeg EJ, Männikkö R, Muntoni F
Modulation of sodium channel gating
Principal investigators: Ruben, Peter
Tracking the fate of TTX-bound sodium channels.
Principal investigators: Ruben, Peter
Coevolution of tetrodotoxin and voltage-gated sodium channels
Principal investigators: Ruben, Peter
The price of success: biophysical costs of tetrodotoxin resistance in voltage-gated sodium channels
Principal investigators: Ruben, Peter
The price of success: biophysical costs of tetrodotoxin resistance in voltage-gated sodium channels
Principal investigators: Ruben, Peter
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- David Wishart and Janis Dionne: 1 shared paper
- David Wishart and Peter Ruben: 1 shared paper
- Clara van Karnebeek and Peter Ruben: 1 shared paper
- Janis Dionne and Peter Ruben: 1 shared paper
- Pediatrics
- Biomedical Physiology and Kinesiology
- Departments of Biological Sciences and Computing Science - University of Alberta
Co-authors at Simon Fraser University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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