Faculty profile
Christopher Maxwell
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Research
Latest papers
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Seminars in cancer biology · 2015
YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.
Stem cells (Dayton, Ohio) · 2014
Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.
Expert reviews in molecular medicine · 2010
Latest funding
- $998,395
Targeting breast involution for the primary prevention of breast cancer among women who inherit a pathogenic variant in breast cancer 1 (BRCA1)
CIHR · 2025 · Nominated PI
- $100,000
Elucidate the targetable mechanisms underpinning the development of a pregnancy-associated breast cancer in BRCA1 mutation carriers.
CIHR · 2024 · Nominated PI
- $1,074,825
Elucidate the targetable mechanisms underpinning the development of a pregnancy-associated breast cancer in BRCA1 mutation carriers.
CIHR · 2024 · Nominated PI
3 publications.
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M
YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.
Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE
Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.
Stratford AL, Reipas K, Maxwell C, Dunn SE
Targeting breast involution for the primary prevention of breast cancer among women who inherit a pathogenic variant in breast cancer 1 (BRCA1)
Principal investigators: Maxwell, Christopher A; Kotsopoulos, Joanne; Lim, David W
Keywords: Alveolar Development; Biomarkers; Brca1; Breastfeeding/Lactation; Epidemiology; Hereditary Breast Cancer; Involution; Pregnancy; Primary Prevention; Prolactin
Elucidate the targetable mechanisms underpinning the development of a pregnancy-associated breast cancer in BRCA1 mutation carriers.
Principal investigators: Maxwell, Christopher A
Keywords: Alveologenesis; Asymmetric Cell Division; Brca1; Cytokinesis; Hereditary Breast Cancer; Involution; Mitosis; Oriented Cell Division; Pregnancy-Associated Breast Cancer
Elucidate the targetable mechanisms underpinning the development of a pregnancy-associated breast cancer in BRCA1 mutation carriers.
Principal investigators: Maxwell, Christopher A
Keywords: Alveologenesis; Asymmetric Cell Division; Brca1; Cytokinesis; Hereditary Breast Cancer; Involution; Mitosis; Oriented Cell Division; Pregnancy-Associated Breast Cancer
Elucidating the mitotic mechanisms that are needed for alveologenesis in the pregnant mammary gland and are likely to be disturbed in pregnancy-associated breast cancer.
Principal investigators: Maxwell, Christopher A
Keywords: Alveologenesis; Asymmetric Cell Division; Brca1; Cytokinesis; Hereditary Breast Cancer; Involution; Mitosis; Oriented Cell Division; Pregnancy-Associated Breast Cancer
Targeting CD47 in pediatric acute lymphoblastic leukemia.
Principal investigators: Lim, Chinten J
Keywords: Cd47; Cell Death; Cell Survival; Chemotherapy; Leukemia; Macrophages; Oncogenic Drivers; Phagocytosis; Proteomics; Signal Transduction
Mechanisms that impact the cell division axis and phenotype for BRCA1-mutant mammary epithelial cells.
Principal investigators: Maxwell, Christopher A
Keywords: Brca1; Cell Fate/ Differentiation; Cell Proliferation; Inherited Disease
Control of symmetric cell division by the spindle assembly factor HMMR
Principal investigators: Maxwell, Christopher
Molecules and mechanisms that regulate asymmetric cell division
Principal investigators: Maxwell, Christopher
Control of cell division by RHAMM in child development and human health
Principal investigators: Maxwell, Christopher A
Keywords: Aurora A; Brca1; Cell Differentiation; Cell Division; Child Health; Hereditary Cancer; Rhamm; Tpx2; Translational Aspects Of The Cell Cycle; Women'S Health
Understanding the mitotic and non-mitotic roles of RHAMM, a novel regulator for aurora kinase A.
Principal investigators: Maxwell, Christopher A
Keywords: Aurora Kinase A; Cell Division; Centrosome; Mitotic Spindle; Nucleocytoplasmic Transport; Rhamm; Tpx2; Translational Aspects Of Cell Cycle
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Christopher Maxwell and Vasundara Venkateswaran: 1 shared paper
- Christopher Maxwell and Satya Prakash: 1 shared paper
- Vasundara Venkateswaran and Satya Prakash: 1 shared paper
- Pediatrics
- Biomedical Engineering
- Surgery
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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