Faculty profile
David Granville
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Latest papers
From good to great: The journey of sustained academic improvement of a university department of pathology and laboratory medicine.
Academic pathology · 2025
Latest funding
- $120,000
Granzyme K: A Novel Mediator of Pruritus in Psoriasis
CIHR · 2025 · Supervisor
- $210,000
Granzyme B as a potential therapeutic target for rheumatoid arthritis
CIHR · 2024 · Supervisor
- $1,051,875
Extracellular Granzyme B Accumulates with Aging and Promotes Age-related Macular Degeneration (AMD)
CIHR · 2024 · Co-investigator
1 publications.
From good to great: The journey of sustained academic improvement of a university department of pathology and laboratory medicine.
Gao ZH, McMillan G, Wellington C, Cote H, Nimmo M, Huntsman D, Vercauteren S, Perrone L, Granville D, Laule C
Granzyme K: A Novel Mediator of Pruritus in Psoriasis
Principal investigators: Sidhu, Jhunam
Keywords: Granzyme K; Imiquimod-Induced Model Of Psoriasis; Immunohistochemistry; Inflammation; Itch; Proteomics; Pruritus; Psoriasis; Sensory Neurons; Serine-Proteases
Granzyme B as a potential therapeutic target for rheumatoid arthritis
Principal investigators: Aubert, Alexandre
Keywords: Extracellular Matrix; Granzymes; In Vivo Antigen-Induced Arthritis Model; Inflammation; Knockout Mouse; Patient Synovial Fluid And Serum; Proteomic Approach; Rheumatoid Arthritis; Serine Protease; Therapeutic Approach
Extracellular Granzyme B Accumulates with Aging and Promotes Age-related Macular Degeneration (AMD)
Principal investigators: Matsubara, Joanne A; Ju, MyeongJin
Keywords: Age-Related Macular Degeneration; Cell Culture; Extracellular Matrix; Healthy Aging; Mast Cell; Mouse Models; Outer Blood Retinal Barrier; Pathological Aging; Protease
Preventing abnormal blood vessel growth in age-related macular degeneration by inhibiting granzyme B activity
Principal investigators: Yoo, Hyung Suk
Keywords: Age-Related Macular Degeneration; Choroidal Neovascularization; Retinal Neurodegeneration; Subretinal Fibrosis
Granzyme B Mediated Pathogenesis in SJS/TEN: Exploring Dermal-Epidermal Junction Disruption and Inflammatory Responses
Principal investigators: Lane, Michael M
Keywords: Adverse Drug Reaction; Blistering; Granzyme B; Immune-Mediated; Immunohistochemistry; Immunoprecipitation; Recombinant Protein Purification; Rna Sequencing; Skin; Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Novel mechanisms and therapeutic approach for aging-related pruritus
Principal investigators: Granville, David J
Keywords: Aging; Chronic; Cytokines; Granzyme B; Granzymes; Itch; Proteases; Proteomics; Pruritus; Small Molecule Inhibitor
Prize 202203PJT - Novel mechanisms and therapeutic approach for aging-related pruritus
Principal investigators: Granville, David J
Keywords: Aging; Chronic; Cytokines; Granzyme B; Granzymes; Itch; Proteases; Proteomics; Pruritus; Small Molecule Inhibitor
Novel mechanisms and therapeutic approach for aging-related pruritus
Principal investigators: Granville, David J
Keywords: Aging; Chronic; Cytokines; Granzyme B; Granzymes; Itch; Proteases; Proteomics; Pruritus; Small Molecule Inhibitor
Targeting TSLP - Novel anti-inflammatory compounds for the treatment and prevention of atopic diseases
Principal investigators: Hedtrich, Sarah
Keywords: Atopic Diseases; Drug Discovery And Development; Inflammatory Skin Diseases; New Anti-Inflammatory Drugs; Topical Drug Delivery; Tslp Inhibitors
Granzyme B: A novel therapeutic target in cutaneous leishmaniasis
Principal investigators: Nabai, Layla
Keywords: Cutaneous Leishmaniasis; Granzyme B
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pathology and Laboratory Medicine
- Molecular Oncology
- Pediatrics
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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