Faculty profile
James Johnson
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Diabetes · 2021
Latest funding
- $891,226
Targeting Scn9a Na+ channels for beta cell survival and disease modification in type 1 diabetes
CIHR · 2025 · Nominated PI
- $898,876
Hyperinsulinemia in pancreatic cancer progression and mortality
CIHR · 2025 · Co-investigator
- $100,000
Targeting Scn9a Na+ channels for beta cell survival and disease modification in type 1 diabetes
CIHR · 2024 · Nominated PI
1 publications.
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, Symposium planning committee, moderators, and speakers:, Rosenblum N, Cefalu W, Andersen DK, Arreaza-Rubín G, Dhara C, James SP, Makarchuk MJ, Pin CL, Sato S, Verchere B, Woo M, Powers A, Estall J, Hoesli C, Millman J, Linnemann A, Johnson J, Pin CL, Hawkins M, Woo M, Gloyn A, Cefalu W, Rosenblum N, Huising MO, Benninger RKP, Almaça J, Hull-Meichle RL, MacDonald P, Lynn F, Melero-Martin J, Yoshihara E, Stabler C, Sander M, Evans-Molina C, Engin F, Thompson P, Shalev A, Redondo MJ, Nadeau K, Bellin M, Udler MS, Dennis J, Dash S, Zhou W, Snyder M, Booth G, Butte A, Florez J
Targeting Scn9a Na+ channels for beta cell survival and disease modification in type 1 diabetes
Principal investigators: Johnson, James D
Keywords: Excitotoxicity; Fda-Approved Drugs; Glucose-Stimulated Insulin Secretion; Lead Compound Mechanistic Studies; Pancreatic Islet Beta-Cells; Pre-Clinical Research; Programmed Cell Death; Tissue-Specific Knockout Mouse Model; Type 1 Diabetes; Voltage-Gated Sodium Channels
Hyperinsulinemia in pancreatic cancer progression and mortality
Principal investigators: Kopp, Janel
Keywords: Diabetes; Glucose; Hyperinsulinemia; Insulin; Kras Inhibitors; Kras/Mapk/Erk; Orthotopic Tumor Transplantation; Pancreatic Ductal Adenocarcinoma; Patient Derived Tumor Organoids; Pi3k/Akt/Mtor
Targeting Scn9a Na+ channels for beta cell survival and disease modification in type 1 diabetes
Principal investigators: Johnson, James D
Keywords: Fda-Approved Drug Repurposing; Glucose-Stimulated Insulin Secretion; Pancreatic Islet Beta-Cells; Pre-Clinical Research; Programmed Cell Death; Tissue-Specific Knockout Mouse Model; Type 1 Diabetes; Voltage-Gated Sodium Channels
Remission Possible: Harnessing Innovative Social Media Strategies to Make Remission of Type 2 Diabetes Possible Across Canada
Principal investigators: Little, Jonathan P; Hoekstra, Femke
Keywords: Awareness; Knowledge Translation; Lifestyle Change; Remission; Social Media; Story-Telling; Type 2 Diabetes
Effects of Voclosporin on Type 1 Diabetes Progression
Principal investigators: Chen, Sing-Young
Keywords: Immunosuppression; Type 1 Diabetes
Leveraging biological sex and genetics for beta cell-directed precision medicine in type 1 diabetes
Principal investigators: Rideout, Elizabeth J; Johnson, James D; Luciani, Dan S; Thompson, Peter; Verchere, Bruce C
Keywords: Beta Cells; Biological Sex; Endoplasmic Reticulum Stress; Extracellular Vesicles; Genetics; Insulin; Mrna Translation; Precision Medicine; Protein Processing; Type 1 Diabetes
Targeting sodium channels for beta-cell protection and insulin secretion in diabetes
Principal investigators: Johnson, James D
Keywords: Excitotoxicity And Programmed Cell Death; Glucose-Stimulated Insulin Secretion; Obesity; Pancreatic Islet Beta-Cells; Type 1 Diabetes; Type 2 Diabetes; Voltage-Gated Sodium Channels
Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes
Principal investigators: Johnson, James D; Luciani, Dan S; Rideout, Elizabeth J; Thompson, Peter; Verchere, Bruce C
Keywords: Autophagy And Lysosomal Protein Homeostasis; Extracellular Vesicles And Exosomes; Human Islet Studies; Insulin Transcription; Insulin Translation; Molecular Mechanisms Of Type 1 Diabetes; Pancreatic Beta-Cell Biology; Pre-Clinical Genetically Engineered Mouse Models; Prohormone Processing
Generation of a functionally robust stem cell based therapy for type 1 diabetes
Principal investigators: Lynn, Francis C; Bruin, Jennifer E; Levings, Megan K; MacDonald, Patrick E; Verchere, Bruce C
Keywords: Embryonic Stem Cells; Functional Maturation; Genome Editing; Insulin Producing Cells; Insulin Secretion; Pancreatic Islets; Single Cell Analyses; Transplantation
Mechanisms linking reduced circulating insulin to insulin sensitivity and longevity
Principal investigators: Johnson, James D
Keywords: Insulin; Insulin Resistance; Knockout Mice; Longevity; Metabolism; Molecular Mechanisms; Proteomics; Transcriptomics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Cellular and Physiological Sciences
- Surgery
- Medical Genetics
- Geography, Environment and Geomatics
- Medicine
- Department of Paediatrics
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Bruce Verchere
Surgery
1 shared papers, latest 2021
Minna Woo
Medicine
1 shared papers, latest 2021
James Johnson
Faculty
1 shared papers, latest 2021
Gillian Booth
Geography, Environment and Geomatics
1 shared papers, latest 2021
Francis Lynn
Medical Genetics
1 shared papers, latest 2021
Satya Dash
Faculty
1 shared papers, latest 2021
Patrick MacDonald
Surgery
1 shared papers, latest 2021
Gillian Booth
Faculty
1 shared papers, latest 2021
Peter Thompson
Cellular and Physiological Sciences
1 shared papers, latest 2021
Francis Lynn
Faculty
1 shared papers, latest 2021
Bruce Verchere
Faculty
1 shared papers, latest 2021
Norman Rosenblum
Department of Paediatrics
1 shared papers, latest 2021
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