Faculty profile
Laura Evgin
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Research
Latest papers
A Living Archive of High-risk Lymphoma.
Blood cancer discovery · 2026 · first author
Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity.
Science advances · 2026
Ionizing radiation enhances CAR T-cell infiltration and efficacy in solid tumors.
Frontiers in immunology · 2026
Latest funding
- $20,000
Autoimmune Biomedical Collaborative (ABC) Annual Workshop
CIHR · 2025 · Co-investigator
Bridging gastric cancer biology to prevent progression of pre-cancerous gastric lesions
CIHR · 2025 · Co-investigator
- $1,028,926
Copper Associated Immunogenic Cell Death: Improving the Therapeutic Potential of Immune Check Point Inhibitors for the Treatment of Metastatic Bladder Cancer
CIHR · 2024 · Principal investigator
13 publications.
A Living Archive of High-risk Lymphoma.
Evgin L, Steidl C
Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity.
Liseth O, Appleton E, Kendall B, Thompson J, Sangsuwannukul T, Tonne J, Diaz RM, Evgin L, Patrikeev A, Sarbia N, Foo S, Harrington K, Ono M, Melcher A, Vile R
Ionizing radiation enhances CAR T-cell infiltration and efficacy in solid tumors.
Zhan L, Clark MA, Loos P, Lee CM, Paulus LER, Shi R, Sekhon PK, Piret JM, Evgin L, Bennewith KL
Phenotypic Characterization and Prognostic Impact of CD103+ Tissue-Resident Memory T Cells in Diffuse Large B-cell Lymphoma.
Savage G, Milne K, Collinge B, Yin Y, Loos P, Warren ME, Laumont CM, Keith D, Nelson BH, Venturutti L, Weng AP, Scott DW, Steidl C, Evgin L
T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy.
Sangsuwannukul T, Kendall B, Tonne J, Liseth O, Thompson J, Supimon K, Metko MM, Chen A, Yerovi MPC, Diaz RM, Evgin L, Webb MJ, van Vloten J, Monga SP, Irshad S, McNiven M, Roberts L, Vile RG
Non-signaling but all important: how the linker, hinge, and transmembrane domains in the CAR hold it all together.
Bernard G, Evgin L
Somatic IRF4 mutations and thymic tropism in primary mediastinal large B-cell lymphoma.
Rai S, Duns G, Frontzek F, Wong JCH, Yin Y, Li MY, Kishida M, Fujisawa M, Healy S, Viganò E, Jiang A, Woolcock B, Telenius A, Ben-Neriah S, Meissner B, Boyle M, Nakamura H, O'Brien L, Cassidy C, Lytle A, Farinha P, Slack G, Hilton LK, Morin RD, Venturutti L, Aoki T, Wretham N, Bush JW, Evgin L, Savage KJ, Scott DW, Steidl C
Minimally modified off-the-shelf allogeneic CAR T cells.
Loos P, Evgin L
Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response.
Webb MJ, Sangsuwannukul T, van Vloten J, Evgin L, Kendall B, Tonne J, Thompson J, Metko M, Moore M, Chiriboga Yerovi MP, Olin M, Borgatti A, McNiven M, Monga SPS, Borad MJ, Melcher A, Roberts LR, Vile R
Direct in vivo CAR T cell engineering.
Short L, Holt RA, Cullis PR, Evgin L
Autoimmune Biomedical Collaborative (ABC) Annual Workshop
Principal investigators: Horwitz, Marc S
Keywords: Autoimmune Diseases; Basic-Clinical Research Partnerships; Common Mechanisms; Interdisciplinary Approaches; Knowledge Dissemination; Patient Advocacy; Resource Sharing; Therapeutics
Bridging gastric cancer biology to prevent progression of pre-cancerous gastric lesions
Principal investigators: Tai, Isabella T; Birol, Inanc; Morin, Gregg B
Keywords: Genomic Evolution Of Normal Tissue To Intestinal Metaplasia
Copper Associated Immunogenic Cell Death: Improving the Therapeutic Potential of Immune Check Point Inhibitors for the Treatment of Metastatic Bladder Cancer
Principal investigators: Bally, Marcel B; Evgin, Laura E
Keywords: Cancer; Combinations; Copper; Icd-Immunogenic Cell Death; Immune Check Point Inhibitors (Cpis); Immunotherapy; Liposomes; Metal Chemistry; Metastatic Bladder Cancer (Mblc); Small Molecules
Engineering tissue-resident memory CAR T cells for treatment of extranodal B cell lymphomas
Principal investigators: Savage, Gillian M
Keywords: Chimeric Antigen Receptor T Cell Therapy; Extranodal Lymphoma; Immunotherapy; Lymphoma Therapy; Murine Models; Tissue Resident Memory T Cells
Canada Research Chair - Tier 2
Principal investigators: Evgin, Laura E
Keywords: Crc
Preclinical multilaboratory studies for cancer immunotherapy
Principal investigators: Tai, Lee-Hwa; Bell, John C; Lalu, Manoj M
Keywords: Cancer Immunotherapy; Chimeric Antigen Receptor T Cell Therapy; Experimental Rigour; Multilaboratory Study; Natural Killer Cell Therapy; Oncolytic Virus Therapy; Translation; Tumour Infiltrating Lymphocyte Therapy
Leveraging TCR reactivity to improve CAR T therapy
Principal investigators: Evgin, Laura E
Keywords: Adoptive T Cell Therapy; Cancer Immunotherapy; Chimeric Antigen Receptor; Lipid Nanoparticle; Lymphoma; Mrna Vaccine; Oncolytic Virus; T Cell Receptor; Vesicular Stomatitis Virus
Development of LNP/mRNA systems for direct transfection and generation of functional Chimeric Antigen Receptor (CAR) T-cells in-vivo for treatment of blood and other cancer cell types
Principal investigators: Cullis, Pieter R
Keywords: Cancer; Cart Therapy; Gene Therapy; Immunotherapy; Lipid Nanoparticles; Mrna
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Experimental Therapeutics
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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