Faculty profile
Michael Underhill
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Research
Latest papers
Sodium cromolyn reduces expression of CTGF, ADAMTS1, and TIMP3 and modulates post-injury patellar tendon morphology.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2011
Latest funding
- $948,600
Deciphering Immune Evasion in Synovial Sarcoma through Interpretable AI and Validation Experiments
CIHR · 2026 · Principal investigator
- $1,120,726
DICER1 tumour predisposition syndrome: dissecting the oncogenic mechanisms with a novel lineage-trackable genetically engineered mouse model
CIHR · 2024 · Co-investigator
- $105,000
Drug Targeting Drivers of Synovial Sarcoma Development
CIHR · 2023 · Supervisor
1 publications.
Sodium cromolyn reduces expression of CTGF, ADAMTS1, and TIMP3 and modulates post-injury patellar tendon morphology.
Sharma A, Abraham T, Sampaio A, Cowan M, Underhill M, Scott A
Deciphering Immune Evasion in Synovial Sarcoma through Interpretable AI and Validation Experiments
Principal investigators: Tang, Xin; Underhill, Michael
Keywords: Ai For Cancer Genomics; Bioinformatics; Cd24/Cd24a; Immune Evasion; Immune-Cold Tumours; Interpretable Ai; Machine Learning For Biomedicine; Mesenchymal Stromal Cells; Single-Cell And Spatial Omics; Synovial Sarcoma
DICER1 tumour predisposition syndrome: dissecting the oncogenic mechanisms with a novel lineage-trackable genetically engineered mouse model
Principal investigators: Huntsman, David G
Keywords: Cancer Predisposition; Dicer1 Tumor Predisposition Syndrome; Genetically Engineered Mouse Model; Mesenchymal Progenitor; Microrna Biogenesis; Sarcoma
Drug Targeting Drivers of Synovial Sarcoma Development
Principal investigators: Wang, Xue Q
Keywords: Chemotherapeutics; Mouse Drug Models]; Single Cell Rna Sequencing; Synovial Sarcoma; Transcriptomics
Translating Epigenomics into Clinical Care for Synovial Sarcoma
Principal investigators: Nielsen, Torsten O
Keywords: Baf; Conditional Mouse Model; Erna; Fusion Oncoprotein; Sarcoma
Mesenchymal progenitors in liver fibrosis - quiescence as a therapeutic target
Principal investigators: Underhill, Michael
Keywords: Cell Lineage Tracing; Cell Quiescence; Genetically Engineered Mouse Models; Liver Fibrosis; Mesenchymal Progenitors; Retinoic Acid Signaling; Single Cell Omics; Therapeutics; Tissue Regeneration/Regrowth; Transcriptomics
Fate and function of mesenchymal progenitors within the medulloblastoma tumour microenvironment
Principal investigators: Underhill, Michael
Keywords: Blood Brain Barrier; Cell Quiescence; Cellular Lineage Tracing; Genetically Engineered Mouse Models; Medulloblastoma; Mesenchymal Progenitor; Pericyte; Single Cell Omics; Therapeutic; Tumor Microenvironment
Tissue-resident mesenchymal progenitors and aging
Principal investigators: Underhill, Michael
Keywords: Aging; Cellular Senescence; Epigenetic Analyses; Fibrosis; Inflammation; Next Generation Sequencing; Single Cell Omics; Stem And Progenitor Cells; Tissue Regeneration; Transgenic And Knockout Mouse Models
Cellular dynamics at the maternal-placental interface
Principal investigators: Beristain, Alexander G
Keywords: Inflammation; Maternal-Fetal Interface; Obesity; Placenta; Pregnancy; Trophoblast Biology; Uterine Natural Killer Cells
Mutation, cell context, and the pathogenesis of ovarian cancer
Principal investigators: Huntsman, David G
Keywords: Endometriosis; Genomic Pathology; Gynecological Cancers; Metastases; Molecular Diagnostics; Molecular Pathology; Pathogenesis; Rare Tumours
Tissue-resident mesenchymal progenitors and aging
Principal investigators: Underhill, Michael
Keywords: Adult Stem Cells; Aging; Fibrosis; Genetic Mouse Models; Mesenchymal Progenitor Cells; Next Generation Sequencing; Progeria Syndromes; Retinoic Acid Signaling; Tissue Regeneration
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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