Faculty profile
Ralph Buttyan
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells.
Endocrine-related cancer · 2023
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.
Nature communications · 2021
Gli activation by the estrogen receptor in breast cancer cells: Regulation of cancer cell growth by Gli3.
Molecular and cellular endocrinology · 2021 · senior author
Latest funding
- $344,250
Interference with Gli to Control Castration Resistant Prostate Cancer
CIHR · 2017 · Nominated PI
- $567,625
Paracrine Hedgehog as a Mediator of Castration Resistant Prostate Cancer
CIHR · 2011 · Nominated PI
22 publications.
Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells.
Yenki P, Bhasin S, Liu L, Nabavi N, Cheng CW, Tam KJ, Peacock JW, Adomat HH, Tombe T, Fazli L, Ivanova L, Dusek C, Khosravi S, Guns EST, Wang Y, Buttyan R, Gleave ME, Ong CJ
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.
Singh N, Ramnarine VR, Song JH, Pandey R, Padi SKR, Nouri M, Olive V, Kobelev M, Okumura K, McCarthy D, Hanna MM, Mukherjee P, Sun B, Lee BR, Parker JB, Chakravarti D, Warfel NA, Zhou M, Bearss JJ, Gibb EA, Alshalalfa M, Karnes RJ, Small EJ, Aggarwal R, Feng F, Wang Y, Buttyan R, Zoubeidi A, Rubin M, Gleave M, Slack FJ, Davicioni E, Beltran H, Collins C, Kraft AS
Gli activation by the estrogen receptor in breast cancer cells: Regulation of cancer cell growth by Gli3.
Massah S, Foo J, Li N, Truong S, Nouri M, Xie L, Prins GS, Buttyan R
Transient Sox9 Expression Facilitates Resistance to Androgen-Targeted Therapy in Prostate Cancer.
Nouri M, Massah S, Caradec J, Lubik AA, Li N, Truong S, Lee AR, Fazli L, Ramnarine VR, Lovnicki JM, Moore J, Wang M, Foo J, Gleave ME, Hollier BG, Nelson C, Collins C, Dong X, Buttyan R
Erythropoietin promotes functional recovery via anti-apoptotic mechanisms in mouse unilateral ureteral obstruction.
Park E, Cox M, Scotland K, Buttyan R, Lange D
The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management.
Ramnarine VR, Kobelev M, Gibb EA, Nouri M, Lin D, Wang Y, Buttyan R, Davicioni E, Zoubeidi A, Collins CC
Inhibition of GLI2 with antisense-oligonucleotides: A potential therapy for the treatment of bladder cancer.
Raven PA, Lysakowski S, Tan Z, D'Costa NM, Moskalev I, Frees S, Struss W, Matsui Y, Narita S, Buttyan R, Chavez-Munoz C, So AI
Correction: A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.
Stylianou N, Lehman ML, Wang C, Fard AT, Rockstroh A, Fazli L, Jovanovic L, Ward M, Sadowski MC, Kashyap AS, Buttyan R, Gleave ME, Westbrook TF, Williams ED, Gunter JH, Nelson CC, Hollier BG
A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.
Stylianou N, Lehman ML, Wang C, Fard AT, Rockstroh A, Fazli L, Jovanovic L, Ward M, Sadowski MC, Kashyap AS, Buttyan R, Gleave ME, Westbrook TF, Williams ED, Gunter JH, Nelson CC, Hollier BG
Correction: Implications of PI3K/AKT inhibition on REST protein stability and neuroendocrine phenotype acquisition in prostate cancer cells.
Chen R, Li Y, Buttyan R, Dong X
Interference with Gli to Control Castration Resistant Prostate Cancer
Principal investigators: Buttyan, Ralph
Keywords: Androgen Receptors; Cancer Cell Growth; Cancer Cell Transcriptome; Computerized Small Molecule Docking; Gli Transcription Factors; Hedgehog Signalling; Prostate Cancer; Therapy Resistance; Three-Dimensional Protein Structure; Tumour Growth
Paracrine Hedgehog as a Mediator of Castration Resistant Prostate Cancer
Principal investigators: Buttyan, Ralph
Keywords: Hedgehog Inihibitors; Hedgehog Signalling; Microrna; Mouse Tumor Xenografts; Paracrine Signalling; Prostate Cancer; Steroid Biosynthesis; Stromal Cells; Testosterone; Tumor Microenvironment
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Urologic Sciences
- Pathology and Laboratory Medicine
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Yuzhuo Wang
Urologic Sciences
4 shared papers, latest 2023
Xuesen Dong
Urologic Sciences
4 shared papers, latest 2020
Colin Collins
Urologic Sciences
3 shared papers, latest 2021
Martin Gleave
Urologic Sciences
3 shared papers, latest 2021
Amina Zoubeidi
Urologic Sciences
2 shared papers, latest 2021
Dirk Lange
Pathology and Laboratory Medicine
2 shared papers, latest 2020
Michael Cox
Urologic Sciences
2 shared papers, latest 2020
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