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Latest papers
Silymarin reverses post-traumatic stress-related anxiety and depression in mice by enhancing monoaminergic systems, inhibiting cytokine release, and reducing astrocytic dysfunction.
Neuroscience · 2026
Silymarin reverses post-traumatic stress-induced memory impairment in mice by containment of oxidative stress, cholinergic dysfunction, and modulation of neuronal caspase-3 expression.
Naunyn-Schmiedeberg's archives of pharmacology · 2026
Human Microglial Molecular Alterations in Aging and Alzheimer's Disease.
Cells · 2026
Latest funding
Investigating the outcomes of senescence on microglial physiological and immune functions: implications for viral infection and Alzheimer's disease pathology along the aging trajectory
CIHR · 2022 · Principal investigator
21 publications.
Silymarin reverses post-traumatic stress-related anxiety and depression in mice by enhancing monoaminergic systems, inhibiting cytokine release, and reducing astrocytic dysfunction.
Emudainohwo JOT, Ben-Azu B, Chijioke BS, Esuku DT, Usin SG, Okpakpor EE, Omotosho OI, Ajayi AM, Ijomone OM, Ozolua RI
Silymarin reverses post-traumatic stress-induced memory impairment in mice by containment of oxidative stress, cholinergic dysfunction, and modulation of neuronal caspase-3 expression.
Emudainohwo JOT, Ben-Azu B, Esuku DT, Chijioke BS, Iwhiwhu P, Usin SG, Okpakpor EE, Oyeniran DA, Ijomone OM, Ozolua RI
Human Microglial Molecular Alterations in Aging and Alzheimer's Disease.
Baldo KAT, Gozlan E, Chidebe EO, Awogbindin I, Ocaña Prieto M, Dalmacio LM, Ben-Azu B, Frenkel D, Tremblay MÈ
Sabinene's neuroprotective effect reverses ketamine-induced experimental schizophrenia in mice through enhancement of cholinergic, antioxidant, and anti-inflammatory mechanisms.
Ben-Azu L, Onyeukwu OB, Chijioke BS, Oboh M, Esuku DT, Adeleke P, Onuelu JE, Ben-Azu B
Microglial response to sleep deprivation depends on the hippocampal region and paradigm used in adult male mice.
Kox J, Picard K, Šimončičová E, Vidal V, Khakpour M, Wilhelm S, Burns S, González Ibáñez F, Ben-Azu B, Havekes R, Tremblay MÈ
Naringin Reverses Chronic Stress-Induced Cognitive Deficits and Enhances Hippocampal Neuroplasticity in Mice.
Ojiakor VO, Ben-Azu B, Ani PN, Ozioko MO, Oviosun A, Ozor II, Esom EA, Anyanwu EG
Diosgenin prevents alcohol-induced intensification of seizures, psychiatric comorbidities, and their neuropathological consequences in kindled epileptic mice.
Ben-Azu B, Chidebe EO, Chijioke BS, Esuku DT, Oritsemuelebi B, Onuelu JE, Iwhiwhu P, Oyovwi OM, Emudainohwo JOT, Uruaka CI, Ajayi AM
Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study.
Cupo L, Vecchiarelli HA, Gallino D, VanderZwaag J, Bradshaw K, Phan A, Khakpour M, Ben-Azu B, Guma E, Fouquet JP, Spring S, Nieman BJ, Devenyi GA, Tremblay ME, Chakravarty MM
Sympathetic-parasympathetic system deregulation theory of aging.
Errico JP, Ben-Azu B, Gargus M, Newell Rogers MK, Tremblay MÈ
In silico and in vivo toxicity assessment of cysteamine-modified nanoparticles: implications for pharmacotherapy application.
Alabi B, Lawal SK, Olojede SO, Suleiman A, Adesanya O, Ochuole DO, Ogunleye FN, Ben-Azu B
Investigating the outcomes of senescence on microglial physiological and immune functions: implications for viral infection and Alzheimer's disease pathology along the aging trajectory
Principal investigators: Tremblay, Marie-Ève; Ben-Azu, Benneth; Frenkel, Dan
Keywords: Aging; Alzheimer; Imaging; Microglia; Molecular Analyses; Mouse; Senescence; Subtypes; Synapses; Viral Infection
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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