Faculty profile

Marie-Ève Tremblay

ResearcherUniversity of Victoria

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Victoria directory, so their courses may be missing. Find their university profile.

Marie-Ève Tremblay

Researcher

Health Sciences

University of Victoria

Victoria, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
21 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (6 CIHR, 1 NSERC), most recently in 2024.
Supervisor on 4 trainee awards (4 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Synapses Crc Aging Microglia Mouse Subtypes Brain Healthy Aging

Latest papers

Editorial: The roles of peripheral immune cells and their circulatory effector molecules in neuropsychiatric disorders, volume II.
Frontiers in cellular neuroscience · 2026
Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice.
Nature neuroscience · 2026
Murine autoantigen-specific type 1 regulatory T cells promote oligodendrogenesis through amphiregulin-EGFR signaling.
Science translational medicine · 2026

All 30 publications

Latest funding

Canada Research Chair - Tier 1
CIHR · 2024 · Nominated PI
$1,400,000
Microglial remodelling of the extracellular matrix: outcomes on synaptic plasticity and behaviour
NSERC · 2024 · Principal investigator
$85,000
A translationally relevant investigation into the impact of chronic sub-intoxicating delta-9-tetrahydrocannabinol (THC) edible consumption on the glial cell regulation of myelination and the subsequent outcomes on cognition in aged male and female mice.
CIHR · 2024 · Supervisor
$120,000

All 14 grants and awards

30 publications.

Editorial: The roles of peripheral immune cells and their circulatory effector molecules in neuropsychiatric disorders, volume II.

Baune BT, Tremblay ME, Bechter K, Tian L

Frontiers in cellular neuroscience2026

DOI: 10.3389/fncel.2026.1976330 PMID: 42774053

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice.

Compagnion AC, Ivanov A, Rana A, Espinoza F, Sandmann T, Martineau FS, Monsorno K, Facchinetti R, Matera A, Rougé L, González Ibáñez F, Catale C, Bizzotto M, Garel S, Matteoli M, Kashiwagi Y, Koyama R, Haass C, Tremblay ME, Beule D, Jelescu I, Zerbi V, Di Paolo G, Paolicelli RC

Nature neuroscience2026

DOI: 10.1038/s41593-026-02348-3 PMID: 42420559

Murine autoantigen-specific type 1 regulatory T cells promote oligodendrogenesis through amphiregulin-EGFR signaling.

Clarke R, Rayatpour A, Garnica J, Lozinski BM, Lee J, Mohapatra S, Yamanouchi J, Moro J, Mondal D, Morch MT, Khakpour M, Murray CJ, Volk C, Tremblay ME, Serra P, Yang Y, Yong VW, Santamaria P

Science translational medicine2026

DOI: 10.1126/scitranslmed.aef2269 PMID: 42455897

Vagus nerve stimulation as an anti-inflammatory therapy for maternal immune activation-induced alterations in offspring microglia and neurodevelopment.

Gargus M, Poyhia L, Errico JP, Rogers MKN, Tremblay ME

Frontiers in neuroscience2026Senior author

DOI: 10.3389/fnins.2026.1827714 PMID: 42110197

Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents.

Leduc-Pessah H, McAllister BB, Sinha S, Stokes-Heck S, Nishizawa D, Fan CY, St-Pierre MK, Bradaia A, Defaye M, Burma NE, Damblon J, Muñoz-Pino E, Visser F, Dorion MF, Healy LM, Tang YM, Canet-Pons J, van den Hoogen NJ, Zhang Z, Antunes FTT, Piscopo VEC, Medina M, Fukuda KI, Ichinohe T, Nagashima M, Hayashida M, Johnson E, Agrawal A, Degenhardt L, Martin NG, Zamponi GW, Nelson EC, Altier C, Tremblay ME, Bousman C, Stifani S, De Koninck Y, Ikeda K, Biernaskie J, Trang T

Neuron2026

DOI: 10.1016/j.neuron.2025.11.018 PMID: 41619726

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study.

Cupo L, Vecchiarelli HA, Gallino D, VanderZwaag J, Bradshaw K, Phan A, Khakpour M, Ben-Azu B, Guma E, Fouquet JP, Spring S, Nieman BJ, Devenyi GA, Tremblay ME, Chakravarty MM

Molecular psychiatry2026

DOI: 10.1038/s41380-025-03189-5 PMID: 40962830

Age-impaired remyelination is associated with dysregulated microglial transitions.

Zia S, Traetta ME, Baaklini CS, Hammond BP, John RK, Souter KM, Meijns N, Afun LKA, Panda S, González Ibáñez F, Burr MK, Dhupia E, Rathod AM, Faria AO, Zaveri D, Challa S, Hahn E, Manesh SB, Lee KV, Ho MFS, Friedman TN, Maguire AD, Pang A, Farkas O, Szulc B, Tenorio L, Vyas D, La Caprara OR, Tetzlaff W, Sinha S, Duncan GJ, Voronova A, Kerr BJ, Tremblay ME, Biernaskie J, Schenk G, Plemel JR

Nature communications2025

DOI: 10.1038/s41467-025-64906-w PMID: 41224757

Neuroglial responses to bacterial, viral, and fungal neuroinfections.

Awogbindin I, ŠimonČiČová E, Vidal V, Ash C, Tremblay ME

Handbook of clinical neurology2025Senior author

DOI: 10.1016/b978-0-443-19102-2.00027-2 PMID: 40148046

Editorial: The outcomes of pollutants on glia.

Arrifano GP, Augusto-Oliveira M, Tremblay ME, Crespo-Lopez ME

Frontiers in cellular neuroscience2024

DOI: 10.3389/fncel.2024.1444344 PMID: 39049822

Microglial contribution to the pathology of neurodevelopmental disorders in humans.

Matuleviciute R, Akinluyi ET, Muntslag TAO, Dewing JM, Long KR, Vernon AC, Tremblay ME, Menassa DA

Acta neuropathologica2023

DOI: 10.1007/s00401-023-02629-2 PMID: 37656188

Canada Research Chair - Tier 1

Nominated PICIHR2024Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Tremblay, Marie-Ève

Keywords: Crc

$1,400,000

Microglial remodelling of the extracellular matrix: outcomes on synaptic plasticity and behaviour

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Tremblay, Marie-Eve

Keywords: microglia; extracellular matrix; synaptic plasticity; behaviour; mouse; adulthood; physiology; chronic stress; imaging; electrophysiology

$85,000

A translationally relevant investigation into the impact of chronic sub-intoxicating delta-9-tetrahydrocannabinol (THC) edible consumption on the glial cell regulation of myelination and the subsequent outcomes on cognition in aged male and female mice.

SupervisorCIHR2024Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Murray, Colin

Keywords: Aging; Behaviour; Cannabis; Cognitive Decline; Magnetic Resonance Imaging; Microscopy; Myelination; Oligodendrocyte Lineage Cells

$120,000

Camera system for Transmission Electron Microscope

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Novales Flamarique, Inigo

Keywords: aquaculture; bacterial research; cellular ultrastructure; deep sea vents; eukaryotic microbes; glial cells and brain disorders; polymer manufacturing; retinal development and disease; symbionts and agricultural pests; transmission electron microscopy

$150,000

Forever Young: Brain Health and Aging

Principal investigatorCIHR2023CIHR Café Scientifique Program - Open Pool

Principal investigators: Gawryluk, Jodie R; Tremblay, Marie-Ève

Keywords: Aging; Brain; Healthy Aging

$6,000

Impact of Psilocybin on Microglial Activity in a Mouse Model of Major Depressive Disorder

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: VanderZwaag, Jared C

Keywords: Major Depressive Disorder; Microglia; Microscopy; Mouse Model; Neuroinflammation; Phagocytosis; Psilocybin; Psychedelics; Serotonin; Synaptic Plasticity

$105,000

Investigating the outcomes of senescence on microglial physiological and immune functions: implications for viral infection and Alzheimer's disease pathology along the aging trajectory

Nominated PICIHR2022Joint Canada-Israel Health Research Program

Principal investigators: Tremblay, Marie-Ève; Ben-Azu, Benneth; Frenkel, Dan

Keywords: Aging; Alzheimer; Imaging; Microglia; Molecular Analyses; Mouse; Senescence; Subtypes; Synapses; Viral Infection

Dark microglia's relationships with Alzheimer's disease hallmarks in late-onset patients.

SupervisorCIHR2022Summer Program in Aging

Principal investigators: Lau, Victor

Keywords: Cellular Senescence; Collaboration With People With Lived Experience; Correlative Study; Electron Microscopy; Late-Onset Alzheimer'S; Microglia Subtypes; Prefrontal Cortex, Braak Stages Iii-Iv; Tau Pathology: Neuritic Plaques, Neurofibrillary Tangles

Reelin, sex, depression, and development of a novel pharmacotherapy and biomarkers

Co-investigatorCIHR2022Project Grant

Principal investigators: Caruncho, Hector J

Keywords: Animal Models; Antidepressants; Biomarkers; Hippocampus; Hypothalamus; Major Depression; Neuroinflammation; Peripheral Inflammation; Reelin; Sex Variability

$100,000

Investigating dark microglia during normal postnatal development and following maternal immune activation

Nominated PICIHR2021Project Grant

Principal investigators: Tremblay, Marie-Ève

Keywords: Behaviour; Human; Maternal Immune Activation; Metabolism; Microglia; Microscopy; Mouse; Subtypes; Synapses; Vasculature

$1,051,876

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Marie-Ève Tremblay

Research

Latest papers

Latest funding

Editorial: The roles of peripheral immune cells and their circulatory effector molecules in neuropsychiatric disorders, volume II.

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice.

Murine autoantigen-specific type 1 regulatory T cells promote oligodendrogenesis through amphiregulin-EGFR signaling.

Vagus nerve stimulation as an anti-inflammatory therapy for maternal immune activation-induced alterations in offspring microglia and neurodevelopment.

Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents.

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study.

Age-impaired remyelination is associated with dysregulated microglial transitions.

Neuroglial responses to bacterial, viral, and fungal neuroinfections.

Editorial: The outcomes of pollutants on glia.

Microglial contribution to the pathology of neurodevelopmental disorders in humans.

Microglial remodelling of the extracellular matrix: outcomes on synaptic plasticity and behaviour

Camera system for Transmission Electron Microscope

Frequent collaborators

Marie-Ève Tremblay

Guy Boivin

Denis Soulet

Benneth Ben-Azu

Chad Bousman

Julie Ottoy

Guy Poirier

Yves De Koninck

Tuan Trang

Armen Saghatelyan

Eric Boilard

Pere Santamaria

Francesca Cicchetti

Jacques Corbeil

Marc Pouliot

Clémence Belleannée

Martin Parent

Anastassia Voronova

Christophe Altier

Abid Oueslati

Stefano Stifani

Wolfram Tetzlaff