Faculty profile
Fraser Hof
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Read how they describe their research on their University of Victoria profile.
Latest papers
Co-assembly modulates a single dye to achieve complex functional outcomes: turn-on sensing, turn-off sensing, and analyte specificity through complexity.
Chemical science · 2026 · senior author
Synthesis and structure-activity relationships of small-molecule 2-pyridone based CBX7 inhibitors.
RSC medicinal chemistry · 2026 · senior author
Synthesis and machine learning techniques to enable data-driven investigation of supramolecular host-guest interactions.
Chemical science · 2026
Latest funding
- $84,000
Complex supramolecular systems and high-affinity hosts for biological applications
NSERC · 2024 · Principal investigator
- $1,443,197
National Invention to Innovation (i2I) Network
NSERC · 2023 · Co-investigator
- $149,683
Automated Synthesizer for Diversity-Oriented Synthesis of Peptides and Peptoids
NSERC · 2020 · Principal investigator
63 publications.
Co-assembly modulates a single dye to achieve complex functional outcomes: turn-on sensing, turn-off sensing, and analyte specificity through complexity.
Baker S, Leonard NA, Desnoyer M, Berezowski F, Selinger AJ, Wilson CR, Bohne C, Hof F
Synthesis and structure-activity relationships of small-molecule 2-pyridone based CBX7 inhibitors.
Wilson CR, Chen EFW, Shaurya A, Sheppard RJ, Andrews DM, Hof F
Synthesis and machine learning techniques to enable data-driven investigation of supramolecular host-guest interactions.
Shaurya A, Bagherzadeh Mostaghimi AH, Turnbull DR, Hof F, Van Humbeck JF
Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens.
Demirsoy E, Parkin TI, Mihalynuk SE, Dema AH, Corrie L, Heilker ME, Kuecks-Winger HN, Yanai A, Birol UB, McIlwee M, de Wet K, Knipscheer M, Bowes V, Tuytel V, Ritchie L, Köster W, Berberov E, Cox WR, Kotkoff M, Thompson VC, Warren RL, Fraser E, Hoang LMN, Hof F, Birol F, Helbing CC, Birol I
Information-rich sensors by assembly: a review on the use of macrocyclic hosts in the context of complex chemical systems.
Selinger AJ, Hof F
Pharmacological targeting of CBX7 alters the epigenetic landscape and induces differentiation of leukemic cells.
de Groot AP, Wilson CR, Weersing E, Pouw JS, Dethmers-Ausema A, Nguyen H, Chen EFW, Shaurya A, Smit L, Hof F, de Haan G
Extended Sulfo-Pillar[6]arenes ─ a New Host Family and Its Application in the Binding of Direct Oral Anticoagulants.
Wilson CR, Puckett AO, Murray IM, Oliver AG, Hof F
Mixed host co-assembled systems for broad-scope analyte sensing.
Selinger AJ, Krämer J, Poarch E, Hore D, Biedermann F, Hof F
De novo synthetic antimicrobial peptide design with a recurrent neural network.
Li C, Sutherland D, Richter A, Coombe L, Yanai A, Warren RL, Kotkoff M, Hof F, Hoang LMN, Helbing CC, Birol I
Adaptive Supramolecular Networks: Emergent Sensing from Complex Systems.
Selinger AJ, Hof F
Complex supramolecular systems and high-affinity hosts for biological applications
Principal investigators: Hof, Fraser
Keywords: supramolecular chemistry; host-guest chemistry; macrocycles; systems chemistry; molecular sensors; fluorescence; organic synthesis; noncovalent interactions; drug binding; dynamic systems
National Invention to Innovation (i2I) Network
Principal investigators: Maine, Elicia
Keywords: Science innovation; Deep tech innovation; STEM entrepreneurship; Knowledge mobilization; Skills training; Entrepreneurial education; Commercialization postdoc; Mentorship; IP strategy; Commercialization strategy
Automated Synthesizer for Diversity-Oriented Synthesis of Peptides and Peptoids
Principal investigators: Hof, Fraser
Ultra-High Performance Liquid Chromatography as a High-Throughput Analytics Platform for Organic Chemistry
Principal investigators: Leitch, David
Diversity-driven supramolecular and systems chemistry for biological applications
Principal investigators: Hof, Fraser
Keywords: Affinity reagents; Diversity-oriented synthesis; Fluorescence; Host-guest chemistry; Macrocycles; Molecular recognition; Peptides and proteins; Phage display; Salt and solute effects; Self-assembly
MethylTrap : chemical affinity reagents for reliable and reproducible PTM-targeted proteomics - Phase 1 application
Principal investigators: Hof, Fraser
An ion mobility spectrometry-high resolution tandem mass spectrometer
Principal investigators: McIndoe, Jason
Identifying bioisosteres for cationic epigenetic motifs
Principal investigators: Hof, Fraser
Multimode microplate reader and automated liquids handling system
Principal investigators: Hof, Fraser
Defining methylation signatures in yeast to improve commercial brewing
Principal investigators: Hof, Fraser
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Inanc Birol and Fraser Hof: 4 shared papers
- Fraser Hof and Irina Paci: 4 shared papers
- Cornelia Bohne and Fraser Hof: 3 shared papers
- Reuven Gordon and Fraser Hof: 2 shared papers
- Dennis Hore and Fraser Hof: 1 shared paper
- Reuven Gordon and Irina Paci: 1 shared paper
- Reuven Gordon and Eugenia Kumacheva: 1 shared paper
- Reuven Gordon and Wei Li: 1 shared paper
- Fraser Hof and Eugenia Kumacheva: 1 shared paper
- Fraser Hof and Wei Li: 1 shared paper
- Eugenia Kumacheva and Wei Li: 1 shared paper
- Chemistry
- Genome Sciences Centre
- Electrical and Computer Engineering
- Chemistry (St. George Campus)
- Microeconomics
Co-authors at University of Victoria, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Irina Paci
Chemistry
4 shared papers, latest 2020
Inanc Birol
Genome Sciences Centre
4 shared papers, latest 2026
Cornelia Bohne
Chemistry
3 shared papers, latest 2026
Reuven Gordon
Electrical and Computer Engineering
2 shared papers, latest 2014
Eugenia Kumacheva
Chemistry (St. George Campus)
1 shared papers, latest 2014
Wei Li
Microeconomics
1 shared papers, latest 2014
Dennis Hore
Chemistry
1 shared papers, latest 2024
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Profile data last refreshed on September 27, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.