Janilyn Arsenio, University of Manitoba

Research

Crc Cytokines Autoimmune-Related Diseases Cancer Immunology Host-Pathogen Interactions Immunology Infectious Disease Vaccines And Immunotherapies

Latest papers

Early sex-related transcriptional differences in CD8+ T cells responding to chronic viral infection reveal a sex bias in exhaustion.
Frontiers in immunology · 2026 · senior author
Protocol for multi-organ isolation of murine leukocytes for flow cytometry.
STAR protocols · 2026 · senior author
Persistent antigen is essential for sustaining Leishmania major-specific memory CD4+ T cells and long-term immunity.
Science advances · 2026

All 16 publications

Latest funding

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.
CIHR · 2026 · Co-investigator
$914,176
38th Annual Canadian Society of Immunology (CSI) 2026 meeting
CIHR · 2025 · Principal investigator
$20,000
Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations
CIHR · 2024 · Co-investigator
$100,000

All 9 grants and awards

16 publications.

01

Early sex-related transcriptional differences in CD8+ T cells responding to chronic viral infection reveal a sex bias in exhaustion.

Kahia N, Robertson SM, Rodriguez M, Layug PJ, Vats H, Kannan K, Spicer V, Ozturk-Aptekmann A, Wilkins O, Arsenio J

Frontiers in immunology2026Senior author

DOI: 10.3389/fimmu.2026.1783098 PMID: 42206032

02

Protocol for multi-organ isolation of murine leukocytes for flow cytometry.

Layug PJ, Marcinow A, Sontag D, Mendelson AA, Arsenio J

STAR protocols2026Senior author

DOI: 10.1016/j.xpro.2025.104318 PMID: 41511878

03

Persistent antigen is essential for sustaining Leishmania major-specific memory CD4+ T cells and long-term immunity.

Mou Z, Zayats R, Salako E, Ikeogu N, Onwah SS, Liu D, Hamana H, Kishi H, Tan D, Leung C, Arsenio J, Murooka TT, Uzonna JE

Science advances2026

DOI: 10.1126/sciadv.aeb3345 PMID: 41779843

04

Publisher Correction: An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.

Zagozewski J, Shahriary GM, Morrison LC, Saulnier O, Stromecki M, Fresnoza A, Palidwor G, Porter CJ, Forget A, Ayrault O, Hawkins C, Chan JA, Vladoiu MC, Sundaresan L, Arsenio J, Taylor MD, Ramaswamy V, Werbowetski-Ogilvie TE

Nature communications2026

DOI: 10.1038/s41467-026-70147-2 PMID: 41771917

05

Enumeration, Phenotyping, and Clinical Associations of Tissue-Resident T Cells in the Ecto- and Endocervix of Women Attending a Colposcopy Clinic.

Ssemaganda A, Kahia N, Oo MM, Rozenberg D, Nuhu F, Jahan N, Mulhall F, Downing K, Sandberg B, Elands H, Groff R, Altman AD, Robinson C, Keynan Y, Bernstein CN, Poliquin V, Arsenio J, McKinnon LR

American journal of reproductive immunology (New York, N.Y. : 1989)2026

DOI: 10.1111/aji.70222 PMID: 41758064

06

Sex differences in disease severity and immune responses in murine and human inflammatory arthritis.

Hemshekhar M, O'Neil LJ, Kahia N, Marshall CL, Singh T, Navarrete M, El-Gabalawy H, Mookherjee N, Arsenio J

Biology of sex differences2026Senior author

DOI: 10.1186/s13293-026-00840-w PMID: 41654945

07

Tissue Resident Memory Cells: Friend or Foe?

Chude CF, Uzonna JE, Arsenio J

Immunology2025Senior author

DOI: 10.1111/imm.70024 PMID: 40754695

08

Leveraging large-scale datasets and single cell omics data to develop a polygenic score for cisplatin-induced ototoxicity.

Miao DNR, Wilke MAP, Pham J, Ladha F, Singh M, Arsenio J, Luca E, Dabdoub A, Yang W, Yang JJ, Drögemöller BI

Human genomics2024

DOI: 10.1186/s40246-024-00679-5 PMID: 39380081

09

Sex differences in CD8+ T cell responses during adaptive immunity.

Layug PJ, Vats H, Kannan K, Arsenio J

WIREs mechanisms of disease2024Senior author

DOI: 10.1002/wsbm.1645 PMID: 38581141

10

An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.

Zagozewski J, Shahriary GM, Morrison LC, Saulnier O, Stromecki M, Fresnoza A, Palidwor G, Porter CJ, Forget A, Ayrault O, Hawkins C, Chan JA, Vladoiu MC, Sundaresan L, Arsenio J, Taylor MD, Ramaswamy V, Werbowetski-Ogilvie TE

Nature communications2020

DOI: 10.1038/s41467-020-17357-4 PMID: 32686664

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.

Co-investigatorCIHR2026Project Grant

Principal investigators: O'Neil, Liam J

Keywords: Cigarette Smoking; Citrullination; Disease Risk; First Nations; Neutrophil Extracellular Traps; Preclinical; Proteomics; Rheumatoid Arthritis

$914,176

38th Annual Canadian Society of Immunology (CSI) 2026 meeting

Principal investigatorCIHR2025Planning and Dissemination Grant - Institute Community Support

Principal investigators: Murooka, Thomas T; Arsenio, Janilyn; Banerji, Versha; Ghia, Jean-Eric; Santer, Deanna; Su, Ruey-Chyi; Tremblay, Cedric S

Keywords: Autoimmune-Related Diseases; Cancer Immunology; Host-Pathogen Interactions; Immunology; Infectious Disease; Vaccines And Immunotherapies

$20,000

Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations

Co-investigatorCIHR2024Project Grant - PA: Research in First Nations, Inuit and/or Métis Health

Principal investigators: O'Neil, Liam J

Keywords: Autoantibody; Cigarette Smoking; Citrullination; Collagen Induced Arthritis; First Nations; Neutrophil Extracellular Traps; Neutrophils; Proteomics; Rheumatoid Arthritis; Smoking Cessation

$100,000

Canada Research Chair - Tier 2

Nominated PICIHR2024Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Arsenio, Janilyn

Keywords: Crc

$500,000

Sex as a biological variable in the development of inflammatory arthritis

Principal investigatorCIHR2022Project Grant - PA: Sex and Gender in Health Research (Bridge funding)

Principal investigators: Mookherjee, Neeloffer; Arsenio, Janilyn; O'Neil, Liam J

Keywords: Animal Model Of Arthritis; Cytokines; First Degree Relatives Of Ra Patients; Immune Response; Inflammation; Inflammatory Arthritis; T-Cell Composition

$100,000

Subsets of subsets: investigating Th17 pathways in inflammatory bowel disease and HIV

Principal investigatorCIHR2021Team Grant: P/T Inflammation for Chronic Conditions-HIV/AIDS Research Initiative

Principal investigators: Mckinnon, Lyle R; Arsenio, Janilyn; Murooka, Thomas T

Keywords: Cd4+ T Cells; Cell-Mediated Immunity; Cytokines; Gastrointestinal; Hiv; Inflammatory Bowel Disease; Th17 Cells; Vaginal

$749,700

Single-cell analysis of the molecular regulation of T cell differentiation

Principal investigatorNSERC2019Discovery Launch Supplement

Principal investigators: Arsenio, Janilyn

$12,500

Single-cell analysis of the molecular regulation of T cell differentiation

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Arsenio, Janilyn

$185,000

Canada Research Chair - Tier 2 - CIHR Funded

Nominated PICIHR2017Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Arsenio, Janilyn

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Immunology
Department of Laboratory Medicine and Pathobiology
Developmental Stem Cell Biology
Internal Medicine
Internal Medicine/Immunology
Obstetrics and Gynecology
Medical Microbiology and Infectious Diseases
Other

Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Cynthia Hawkins

Department of Laboratory Medicine and Pathobiology

2 shared papers, latest 2026

Vijay Ramaswamy

Developmental Stem Cell Biology

2 shared papers, latest 2026

Vanessa Poliquin

Obstetrics and Gynecology

1 shared papers, latest 2026

Yoav Keynan

Medical Microbiology and Infectious Diseases

1 shared papers, latest 2026

Alain Dabdoub

Faculty

1 shared papers, latest 2024

Hani El-Gabalawy

Internal Medicine

1 shared papers, latest 2026

Neeloffer Mookherjee

Internal Medicine/Immunology

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Crc Dear Professor Arsenio, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Early sex-related transcriptional differences in CD8+ T cells responding to chronic viral infection reveal a sex bias in exhaustion." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "38th Annual Canadian Society of Immunology (CSI) 2026 meeting" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]