Faculty profile
Tiina Kauppinen
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Research
Latest papers
RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status
Cancers · 2020
Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
Early growth response 2 (Egr-2) expression is triggered by NF-κB activation.
Molecular and cellular neurosciences · 2015
Latest funding
- $1,097,776
Validating a Novel Strategy to Prevent Synaptic Dysfunction in Alzheimer's Disease
CIHR · 2026 · Co-investigator
- $1,158,976
Interplay of Neuroinflammation and Synaptic Plasticity in Neurodegeneration
CIHR · 2020 · Principal investigator
- $1,051,875
Microglia and cognitive impairments in offspring exposed to gestational diabetes mellitus
CIHR · 2018 · Nominated PI
3 publications.
RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status
Sinha A, Saleh A, Endersby R, Yuan SH, Chokshi CR, Brown KR, Kuzio B, Kauppinen T, Singh SK, Baker SJ
Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.
Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA
Early growth response 2 (Egr-2) expression is triggered by NF-κB activation.
Nafez S, Oikawa K, Odero GL, Sproule M, Ge N, Schapansky J, Abrenica B, Hatherell A, Cadonic C, Zhang S, Song X, Kauppinen T, Glazner GW, Grilli M, Czubryt MP, Eisenstat DD, Albensi BC
Validating a Novel Strategy to Prevent Synaptic Dysfunction in Alzheimer's Disease
Principal investigators: Jackson, Michael F
Keywords: Alzheimer'S Disease; Animal Models Of Disease; Cognitive Tests; Electrophysiology; Fluorescence Imaging; Hippocampus; Neuroinflammation; Nmda Receptor Signalling; Pannexins; Synaptotoxicity
Interplay of Neuroinflammation and Synaptic Plasticity in Neurodegeneration
Principal investigators: Jackson, Michael F; Kauppinen, Tiina
Keywords: Alzheimer'S Disease; Behavioral Assay; Electrophysiology; Hippocampus; Inflammation; Microglia; Nmda Receptors; Synaptic Plasticity; Trp Channels
Microglia and cognitive impairments in offspring exposed to gestational diabetes mellitus
Principal investigators: Kauppinen, Tiina
Keywords: Cognitive Functions; Conditional Knock Out Mice; Fetal Programming; Gestational Diabetes Mellitus; Hippocampus; Lentivirus Transduction; Microglia; Neurodevelopment; Neuroinflammation; Synapse
Signaling events regulating microglial functions and activation phenotypes
Principal investigators: Kauppinen, Tiina
Development of magnetic tumor killing nanoparticles to breakthrough the blood-brain barrier
Principal investigators: Miller, Donald W; Klonisch, Thomas; van Lierop, Johan
Keywords: Blood-Brain Barrier; Brain Endothelial Cell; Brain Tumor; Chemotherapeutics; Drug Delivery; Glioblastoma; Hyperthermia; Magnetism; Nanoparticles; Neuroinflammation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pharmacology and Therapeutics
- Surgery
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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