This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of New Brunswick directory, so their courses may be missing. Find their university profile.
Research
Latest papers
A cinnamyl alcohol dehydrogenase-like scaffold organizes monoterpenoid indole alkaloid biosynthesis.
Science (New York, N.Y.) · 2026
Heterologous expression of CrMATE1 increases flux of intermediates in monoterpenoid indole alkaloid pathway.
Plant physiology and biochemistry : PPB · 2026
Yohimban acetylation in Rauvolfia is mediated by a leaf-specific acetyltransferase in reserpine biosynthetic gene cluster.
Plant physiology and biochemistry : PPB · 2026 · senior author
Latest funding
- $90,000
MIMA : Mouvement Intercellulaire des Métabolites Alcaloïdes
NSERC · 2023 · Co-investigator
- $100,236
Compositional Analysis via Magnetic Resonance Relaxation Correlation with a Desktop Permanent Magnet
NSERC · 2022 · Co-investigator
- $150,000
Discovery and engineering the biosynthesis of novel cannabinoid pharmaceuticals
NSERC · 2021 · Principal investigator
22 publications.
A cinnamyl alcohol dehydrogenase-like scaffold organizes monoterpenoid indole alkaloid biosynthesis.
Gao D, Mann SGA, Chen B, Gou Y, Chen C, Qiao C, Garza-Garcia JJO, Shahsavarani M, Jiang X, Tran HC, Bao J, Richardson MB, Li J, Perley JO, Hwang J, Dong F, Dong C, Huang L, De Luca V, Wang Y, Qu Y, Lian J
Heterologous expression of CrMATE1 increases flux of intermediates in monoterpenoid indole alkaloid pathway.
Yeung LS, Perley JO, Germain H, Qu Y, Dastmalchi M
Yohimban acetylation in Rauvolfia is mediated by a leaf-specific acetyltransferase in reserpine biosynthetic gene cluster.
Hwang J, Richardson MB, Kirshner J, Guo J, Perley JO, Albert VA, Deslongchamps G, Qu Y
Four enzymes from button bush enable de novo biosynthesis of spirooxindole alkaloids in yeast.
Seveck AD, Perley JO, Gao D, Lian J, Qu Y
Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion.
Hwang J, Kirshner J, Deschênes DAR, Richardson MB, Fleck SJ, Mann SGA, Guo J, Perley JO, Shahsavarani M, Garza-Garcia JJO, Seveck AD, Doiron SS, Mai Z, Silliphant SN, Englehart SA, Blight BA, Calhoun L, Gao D, Lian J, Deslongchamps G, Albert VA, Qu Y
Regiospecific hydroxylase and O-methyltransferase for the biosynthesis of anticancer alkaloids in Tabernaemontana elegans (toad tree).
Mann SGA, Richardson MB, Young RN, Deslongchamps G, Qu Y
Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis.
Mann SGA, Paz-Galeano M, Shahsavarani M, Perley JO, Guo J, Garza-Garcia JJO, Qu Y
Promiscuous and regiospecific Vinca minor hydroxylases for opioid akuammine biosynthesis and monoterpenoid indole alkaloid diversification.
Mai Z, Richardson MB, Mann SGA, Greene J, Paul AA, Perley JO, Deslongchamps G, Qu Y
Oxidation of four monoterpenoid indole alkaloid classes by three cytochrome P450 monooxygenases from Tabernaemontana litoralis.
Mai Z, Kim K, Richardson MB, Deschênes DAR, Garza-Garcia JJO, Shahsavarani M, Perley JO, Njoku DI, Deslongchamps G, De Luca V, Qu Y
Chemical, pharmacological properties and biosynthesis of opioid mitragynine in Mitragyna speciosa (kratom).
Garza-Garcia JJO, Qu Y
MIMA : Mouvement Intercellulaire des Métabolites Alcaloïdes
Principal investigators: Dastmalchi, Mehran M
Keywords: alkaloids; biochemistry; catharanthus roseus; monoterpenoid indole alkaloids; plant metabolism; plant pathology; pseudomonas; synthetic biology; transport; yeast
Compositional Analysis via Magnetic Resonance Relaxation Correlation with a Desktop Permanent Magnet
Principal investigators: Balcom, Bruce
Discovery and engineering the biosynthesis of novel cannabinoid pharmaceuticals
Principal investigators: Qu, Yang Y
Keywords: Bibenzyl cannabinoid; Biosynthesis; Cannabinoid innovation; Endocannabinoid system; Gene discovery; Inflammation; Metabolic engineering; Pharmaceutical development; Plant specialized metabolism; Yeast genetic engineering
Characterization and engineering of the biosynthesis of alternative painkilling natural products
Principal investigators: Qu, Yang
Keywords: specialized metabolites; biosynthesis; synthetic biology; chemodiversity; monoterpenoid indole alkaloid; cannabinoid; pathway elucidation; pathway reconstitution in microbes; opioid overdose crisis; painkillers
Characterization and engineering of the biosynthesis of alternative painkilling natural products
Principal investigators: Qu, Yang
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Yang Qu and Vincenzo De Luca: 7 shared papers
- Yang Qu and Dae-Kyun Ro: 2 shared papers
- Vincenzo De Luca and Mehran Dastmalchi: 2 shared papers
- Yang Qu and Mehran Dastmalchi: 1 shared paper
- Chemistry
- Biological sciences
- Biological Sciences
- Agricultural and Environmental Sciences, Faculty of
Co-authors at University of New Brunswick, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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