Research
Read how they describe their research on their Acadia University profile.
Latest papers
Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs.
iScience · 2026
LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target.
iScience · 2026
THSD4 is a novel mediator of T cell exclusion and anti-PD-1 resistance in hormone receptor-positive breast cancer.
Biomarker research · 2025
Latest funding
- $1,090,125
Targeting ALDH1A3 and investigating mechanisms of ALDH1A3-mediated breast cancer progression
CIHR · 2023 · Co-investigator
5 publications.
Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs.
MacLean MR, Bernardoni BL, Fernando W, Petrarolo G, D'Agostino I, Dean CA, Venkatesh J, Hughes CS, Goralski KB, Subramanian G, Arun RP, Cahill HF, Walker OL, Thomas LN, Douglas RC, La Motta C, Marcato P
LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target.
Venkatesh J, Wasson MD, Arun RP, Cahill HF, Walker OL, Dean CA, Fernando W, MacLean MR, McLean ME, Khan B, Kruth PS, Sultonova M, Nersesian S, Lee SN, Longjohn MN, Hughes CS, Belbin TJ, Gaston D, Paulo JA, Knapp GC, Bethune G, Gujar S, Boudreau JE, Murphy JP, Marcato P
THSD4 is a novel mediator of T cell exclusion and anti-PD-1 resistance in hormone receptor-positive breast cancer.
Walker OL, Wasson MD, Kumar V, Nersesian S, Venkatesh J, Vijayan VV, Coates L, Fernando W, Arun RP, Cahill HF, Baker E, Dahn ML, Slauenwhite D, Cruickshank BM, Barnes P, Longjohn MN, Belbin TJ, Gaston D, Knapp GC, Melvin J, Gujar S, Boudreau JE, Bethune G, Marcato P
ALDH1A3 is the switch that determines the balance of ALDH+ and CD24-CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer.
Fernando W, Cruickshank BM, Arun RP, MacLean MR, Cahill HF, Morales-Quintanilla F, Dean CA, Wasson MD, Dahn ML, Coyle KM, Walker OL, Power Coombs MR, Marcato P
Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways.
MacLean MR, Walker OL, Arun RP, Fernando W, Marcato P
Targeting ALDH1A3 and investigating mechanisms of ALDH1A3-mediated breast cancer progression
Principal investigators: Marcato, Paola
Keywords: Aldh1a3; Breast Cancer; Exosomes; Metastasis; Microrna; Targeted Therapeutic
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Paola Marcato and Kerry Goralski: 15 shared papers
- Paola Marcato and Jeanette Boudreau: 5 shared papers
- Paola Marcato and Wasundara Fernando: 5 shared papers
- Jeanette Boudreau and Wasundara Fernando: 2 shared papers
- Kerry Goralski and Wasundara Fernando: 1 shared paper
- Department of Pathology
- Department of Microbiology & Immunology
- Department of Pharmacology
- Other
Co-authors at Acadia University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Paola Marcato
Department of Pathology
5 shared papers, latest 2026
Jeanette Boudreau
Department of Microbiology & Immunology
2 shared papers, latest 2026
Thomas Belbin
Oncology
2 shared papers, latest 2026
Shashi Gujar
Department of Pathology
2 shared papers, latest 2026
Kerry Goralski
Department of Pharmacology
1 shared papers, latest 2026
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.