This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Trithorax regulates long-term memory in Drosophila through epigenetic maintenance of mushroom body metabolic state and translation capacity.
PLoS biology · 2025
The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder.
American journal of human genetics · 2023
A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock.
Current biology : CB · 2023
Latest funding
- $10,000
The 17th Canadian Drosophila Research Conference - CanFly2023
CIHR · 2022 · Co-investigator
- $908,820
Circadian clock regulatory mechanisms and the etiology of behavioural disorders
CIHR · 2021 · Nominated PI
- $12,500
Activatable bioluminescence to monitor circadian clock mechanisms in specific Drosophila neurons in vivo
NSERC · 2019 · Principal investigator
12 publications.
Trithorax regulates long-term memory in Drosophila through epigenetic maintenance of mushroom body metabolic state and translation capacity.
Raun N, Jones SG, Kerr O, Keung C, Butler EF, Alka K, Krupski JD, Reid-Taylor RA, Ibrahim V, Williams M, Top D, Kramer JM
The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder.
Rots D, Jakub TE, Keung C, Jackson A, Banka S, Pfundt R, de Vries BBA, van Jaarsveld RH, Hopman SMJ, van Binsbergen E, Valenzuela I, Hempel M, Bierhals T, Kortüm F, Lecoquierre F, Goldenberg A, Hertz JM, Andersen CB, Kibæk M, Prijoles EJ, Stevenson RE, Everman DB, Patterson WG, Meng L, Gijavanekar C, De Dios K, Lakhani S, Levy T, Wagner M, Wieczorek D, Benke PJ, Lopez Garcia MS, Perrier R, Sousa SB, Almeida PM, Simões MJ, Isidor B, Deb W, Schmanski AA, Abdul-Rahman O, Philippe C, Bruel AL, Faivre L, Vitobello A, Thauvin C, Smits JJ, Garavelli L, Caraffi SG, Peluso F, Davis-Keppen L, Platt D, Royer E, Leeuwen L, Sinnema M, Stegmann APA, Stumpel CTRM, Tiller GE, Bosch DGM, Potgieter ST, Joss S, Splitt M, Holden S, Prapa M, Foulds N, Douzgou S, Puura K, Waltes R, Chiocchetti AG, Freitag CM, Satterstrom FK, De Rubeis S, Buxbaum J, Gelb BD, Branko A, Kushima I, Howe J, Scherer SW, Arado A, Baldo C, Patat O, Bénédicte D, Lopergolo D, Santorelli FM, Haack TB, Dufke A, Bertrand M, Falb RJ, Rieß A, Krieg P, Spranger S, Bedeschi MF, Iascone M, Josephi-Taylor S, Roscioli T, Buckley MF, Liebelt J, Dagli AI, Aten E, Hurst ACE, Hicks A, Suri M, Aliu E, Naik S, Sidlow R, Coursimault J, Nicolas G, Küpper H, Petit F, Ibrahim V, Top D, Di Cara F, Genomics England Research Consortium, Louie RJ, Stolerman E, Brunner HG, Vissers LELM, Kramer JM, Kleefstra T
A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock.
Giesecke A, Johnstone PS, Lamaze A, Landskron J, Atay E, Chen KF, Wolf E, Top D, Stanewsky R
Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster.
Johnstone PS, Ogueta M, Akay O, Top I, Syed S, Stanewsky R, Top D
Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network.
Ahmad M, Li W, Top D
Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome.
Kummeling J, Stremmelaar DE, Raun N, Reijnders MRF, Willemsen MH, Ruiterkamp-Versteeg M, Schepens M, Man CCO, Gilissen C, Cho MT, McWalter K, Sinnema M, Wheless JW, Simon MEH, Genetti CA, Casey AM, Terhal PA, van der Smagt JJ, van Gassen KLI, Joset P, Bahr A, Steindl K, Rauch A, Keller E, Raas-Rothschild A, Koolen DA, Agrawal PB, Hoffman TL, Powell-Hamilton NN, Thiffault I, Engleman K, Zhou D, Bodamer O, Hoefele J, Riedhammer KM, Schwaibold EMC, Tasic V, Schubert D, Top D, Pfundt R, Higgs MR, Kramer JM, Kleefstra T
Cell-cell membrane fusion induced by p15 fusion-associated small transmembrane (FAST) protein requires a novel fusion peptide motif containing a myristoylated polyproline type II helix.
Top D, Read JA, Dawe SJ, Syvitski RT, Duncan R
Enhanced fusion pore expansion mediated by the trans-acting Endodomain of the reovirus FAST proteins.
Top D, Barry C, Racine T, Ellis CL, Duncan R
A virus-encoded cell-cell fusion machine dependent on surrogate adhesins.
Salsman J, Top D, Barry C, Duncan R
Bovine lactoferricin causes apoptosis in Jurkat T-leukemia cells by sequential permeabilization of the cell membrane and targeting of mitochondria.
Mader JS, Richardson A, Salsman J, Top D, de Antueno R, Duncan R, Hoskin DW
The 17th Canadian Drosophila Research Conference - CanFly2023
Principal investigators: Kramer, James M
Keywords: Cell Biology; Disease Models; Drosophila; Evolution; Genetics; Molecular Biology; Neurobiology; Physiology
Circadian clock regulatory mechanisms and the etiology of behavioural disorders
Principal investigators: Top, Deniz
Keywords: Behaviour; Circadian Rhythms; Drosophila Melanogaster; Genetics; Mental Health; Neuropsychiatric Disorders; Protein Phosphorylation; Transcription Regulation
Activatable bioluminescence to monitor circadian clock mechanisms in specific Drosophila neurons in vivo
Principal investigators: Top, Deniz
Activatable bioluminescence to monitor circadian clock mechanisms in specific Drosophila neurons in vivo
Principal investigators: Top, Deniz
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Microbiology and Immunology
- Pediatrics/Human Genetics
- Cell Biology
Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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