Faculty profile
Locke Davenport Huyer
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Biomaterial-associated factors in silicone breast implant-related pathology.
Acta biomaterialia · 2026 · senior author
Characterization of Degradation and Mechanics of Electrospun PCL Fibers through Molecular Weight and PEO Blending.
ACS macro letters · 2026
γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response.
Nature communications · 2026
Latest funding
- $975,376
Immunomodulatory Polymer Coatings to Reduce Silicone Breast Implant Pathological Fibrosis
CIHR · 2026 · Nominated PI
- $120,000
Systematic development of novel immunoregulatory itaconate degradable polymer coatings to address silicone breast implant complications.
CIHR · 2025 · Supervisor
- $100,000
Immunomodulatory Polymer Coatings to Reduce Silicone Breast Implant Pathological Fibrosis
CIHR · 2025 · Nominated PI
13 publications.
Biomaterial-associated factors in silicone breast implant-related pathology.
Callaghan NI, Lake R, Fong-Hollohan L, Medd K, Rempe C, Bezuhly M, Davenport Huyer L
Characterization of Degradation and Mechanics of Electrospun PCL Fibers through Molecular Weight and PEO Blending.
Rasouli R, Wheeler B, Davenport Huyer L, Frampton JP
γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response.
Ruta A, Krishnan K, Woo J, Mejías JC, Gray-Gaillard EF, Maestas DR, Nguyen HH, Rindone AN, Cherry C, Patatanian M, Yu FH, Yang B, Amelung C, King CD, Schilling B, Gerecht S, Fertig EJ, Davenport Huyer L, Pardoll DM, Elisseeff JH
Systematic Development of Degradable Polyester Biomaterials via Ring-Opening Copolymerization of Succinic Anhydride and Epoxides.
Murrin SC, Woodworth KE, Wheeler B, Froom ZSCS, Scott AJ, Davenport Huyer L
Persistent glycolysis defines pathological foreign body-associated inflammation to polymeric implants.
Rempe C, Callaghan N, Fong-Hollohan L, Nersesian S, Froom Z, Medd K, Ahmed I, Karakach T, Boudreau JE, Bezuhly M, Davenport Huyer L
Altered Metabolism in Idiopathic Pulmonary Fibrosis.
Callaghan NI, Davenport Huyer L
Molecular and Macroscopic Considerations for Degradable Aliphatic Polyester Biomaterial Design.
Wheeler BP, Medd K, Woodworth KE, Davenport Huyer L
Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics.
Froom ZSCS, Callaghan NI, Davenport Huyer L
Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro-Inflammatory Macrophage Activation.
Woodworth KE, Froom ZSCS, Osborne ND, Rempe CN, Wheeler B, Medd K, Callaghan NI, Qian H, Acharya AP, Charron C, Davenport Huyer L
Antifibrotic Function of Itaconate-Based Degradable Polyester Materials.
Froom ZSCS, Medd K, Wheeler BP, Osborne ND, Rempe CN, Woodworth KE, Charron C, Davenport Huyer L
Immunomodulatory Polymer Coatings to Reduce Silicone Breast Implant Pathological Fibrosis
Principal investigators: Davenport Huyer, Locke S
Keywords: Breast Recontrsuction; Controlled Release; Fibrosis; Immunometabolism; Implantable Medical Devices; Polyester Biomaterials; Polymer Coatings; Survivorship
Systematic development of novel immunoregulatory itaconate degradable polymer coatings to address silicone breast implant complications.
Principal investigators: Froom, Zachary S
Keywords: Degrable Polyesters; Fibrosis; Inflammation; Macrophage-Fibroblast Axis; Pre-Clincial Models
Immunomodulatory Polymer Coatings to Reduce Silicone Breast Implant Pathological Fibrosis
Principal investigators: Davenport Huyer, Locke S
Keywords: Breast Reconstruction; Degradable Polyester; Drug Delivery; Fibrosis; Immunometabolism; Implantable Medical Devices; Inflammation; Mastectomy; Polymer Coatings; Silicone Breast Implants
Immunomodulatory Polymer Coatings to Reduce Silicone Breast Implant Pathological Fibrosis
Principal investigators: Davenport Huyer, Locke S
Keywords: Breast Reconstruction; Degradable Polyester; Drug Delivery; Fibrosis; Immunometabolism; Implantable Medical Devices; Inflammation; Mastectomy; Polymer Coatings; Silicone Breast Implants
Systematic development of degradable itaconate polymer microparticles to achieve intracellular small molecule immunomodulation
Principal investigators: Davenport Huyer, Locke LS
Keywords: biomaterials; degradable polyester; dendritic cells; immunometabolism; immunomodulation; microparticles; polymer synthesis
Low temperature differential scanning calorimeter for characterization of novel materials
Principal investigators: Davenport Huyer, Locke
Keywords: biosourced materials; degradable polymers; inorganic polymers; in vitro systems; material hydration; novel materials; sustainable material design; thermal characterization; thermal transitions
Metabolite-based Immunoregulatory Polymer Surgical Meshes for Pelvic Floor Reconstructive Surgery
Principal investigators: Davenport Huyer, Locke S
Keywords: Degradable Polyesters; Fiber; Fibrosis; Immunoengineering; Immunometabolism; Implantable Medical Devices; Macrophage Inflammation; Surgical Meshes
Design of next-generation degradable polymer materials with immunoregulatory properties
Principal investigators: Davenport Huyer, Locke
Novel cell-responsive and instructive polymer coatings to improve implant-based breast reconstruction
Principal investigators: Davenport Huyer, Locke
Keywords: degradable polymer; fibrosis; capsular contracture; implants; controlled drug release; macrophage; fibroblast; immunometabolism
Novel cell-responsive and instructive polymer coatings to improve implant-based breast reconstruction
Principal investigators: Davenport Huyer, Locke
Keywords: degradable polymer fibrosis capsular contracture implants controlled drug release macrophage fibroblast immunometabolism
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Applied Oral Sciences
- Microbiology and Immunology
- Institute of Biomaterials and Biomedical Engineering
Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.