This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Carleton University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Comparison of gene expression and polycyclic aromatic compound profiles in hepatic tissue of black guillemot (Cepphus grylle) collected from an oil spill site and a non-spill site in the Arctic.
Marine pollution bulletin · 2025
Bioinformatic workflows for deriving transcriptomic points of departure: current status, data gaps, and research priorities.
Toxicological sciences : an official journal of the Society of Toxicology · 2025 · first author
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Toxicological sciences : an official journal of the Society of Toxicology · 2022
Latest funding
- $12,500
Transcriptomic dose-response modeling to support ecological risk assessment
NSERC · 2020 · Principal investigator
- $140,000
Transcriptomic dose-response modeling to support ecological risk assessment
NSERC · 2020 · Principal investigator
12 publications.
Comparison of gene expression and polycyclic aromatic compound profiles in hepatic tissue of black guillemot (Cepphus grylle) collected from an oil spill site and a non-spill site in the Arctic.
Zahaby Y, Crump D, O'Brien J, Dupuis-Smith R, Dwyer-Samuel F, Laing R, Pilgrim S, Gear G, Pamak C, Saunders M, Denniston M, Mallory ML, Tomy G, Halldorson T, Vitharana N, Xia Z, Francisco O, Provencher JF
Bioinformatic workflows for deriving transcriptomic points of departure: current status, data gaps, and research priorities.
O'Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A, Johnson K, Reardon A, Rooney J, Shao K, Stainforth R, Wheeler M, Dalmas Wilk D, Williams A, Yauk C, Costa E
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Johnson KJ, Auerbach SS, Stevens T, Barton-Maclaren TS, Costa E, Currie RA, Dalmas Wilk D, Haq S, Rager JE, Reardon AJF, Wehmas L, Williams A, O'Brien J, Yauk C, LaRocca JL, Pettit S
Temporal change and the influence of climate and weather factors on mercury concentrations in Hudson Bay polar bears, caribou, and seabird eggs.
Morris AD, Braune BM, Gamberg M, Stow J, O'Brien J, Letcher RJ
Developmental and Hepatic Gene Expression Changes in Chicken Embryos Exposed to p-Tert-Butylphenyl Diphenyl Phosphate and Isopropylphenyl Phosphate via Egg Injection.
Nguyen PTT, Pagé-Larivière F, Williams K, O'Brien J, Crump D
Cytotoxic and Transcriptomic Effects in Avian Hepatocytes Exposed to a Complex Mixture from Air Samples, and Their Relation to the Organic Flame Retardant Signature.
Ha K, Xia P, Crump D, Saini A, Harner T, O'Brien J
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach SS, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M
ToxChip PCR Arrays for Two Arctic-Breeding Seabirds: Applications for Regional Environmental Assessments.
Zahaby Y, Xia P, Crump D, Provencher JF, Thomas PJ, Pauli B, Braune BM, Franckowiak RP, Gendron M, Savard G, Sarma SN, Mallory ML, O'Brien J
Corrigendum to "Polycyclic aromatic compounds (PACs) and trace elements in four marine bird species from northern Canada in a region of natural marine oil and gas seeps" [Sci. Total Environ. 744 (2020) 140959].
Provencher JF, Thomas PJ, Pauli B, Braune BM, Franckowiak RP, Gendron M, Savard G, Sarma SN, Crump D, Zahaby Y, O'Brien J, Mallory ML
Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework.
Chauhan V, Wilkins RC, Beaton D, Sachana M, Delrue N, Yauk C, O'Brien J, Marchetti F, Halappanavar S, Boyd M, Villeneuve D, Barton-Maclaren TS, Meek B, Anghel C, Heghes C, Barber C, Perkins E, Leblanc J, Burtt J, Laakso H, Laurier D, Lazo T, Whelan M, Thomas R, Cool D
Transcriptomic dose-response modeling to support ecological risk assessment
Principal investigators: O'Brien, Jason
Transcriptomic dose-response modeling to support ecological risk assessment
Principal investigators: O'Brien, Jason
Keywords: toxicogenomics; ecotoxicology; chemical and environmental risk assessment; dose response modeling; in vitro screening; adverse outcome pathways; mode of action; wildlife
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Carole Yauk and Francesco Marchetti: 5 shared papers
- Carole Yauk and Jason O'Brien: 3 shared papers
- Francesco Marchetti and Jason O'Brien: 1 shared paper
- Jason O'Brien and Gregg Tomy: 1 shared paper
- Biology
- Chemistry
Co-authors at Carleton University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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